Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | HSA00150_ANDROGEN_AND_ESTROGEN_METABOLISM |
| Enrichment Score (ES) | 0.507616 |
| Normalized Enrichment Score (NES) | 1.5461712 |
| Nominal p-value | 0.04054054 |
| FDR q-value | 0.124220245 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | HSD17B7 | HSD17B7 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 7 | 9 | 0.428 | 0.2023 | Yes |
| 2 | UGT2A1 | UGT2A1 Entrez, Source | UDP glucuronosyltransferase 2 family, polypeptide A1 | 201 | 0.173 | 0.2697 | Yes |
| 3 | SULT1E1 | SULT1E1 Entrez, Source | sulfotransferase family 1E, estrogen-preferring, member 1 | 278 | 0.152 | 0.3362 | Yes |
| 4 | HSD11B1 | HSD11B1 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 1 | 318 | 0.147 | 0.4030 | Yes |
| 5 | CYP19A1 | CYP19A1 Entrez, Source | cytochrome P450, family 19, subfamily A, polypeptide 1 | 670 | 0.114 | 0.4305 | Yes |
| 6 | HSD17B3 | HSD17B3 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 3 | 1112 | 0.093 | 0.4414 | Yes |
| 7 | SULT2A1 | SULT2A1 Entrez, Source | sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 | 1153 | 0.091 | 0.4817 | Yes |
| 8 | SRD5A2 | SRD5A2 Entrez, Source | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) | 1342 | 0.085 | 0.5076 | Yes |
| 9 | AKR1D1 | AKR1D1 Entrez, Source | aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase) | 2098 | 0.066 | 0.4822 | No |
| 10 | HSD3B1 | HSD3B1 Entrez, Source | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 | 2646 | 0.056 | 0.4678 | No |
| 11 | HSD17B1 | HSD17B1 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 1 | 3393 | 0.044 | 0.4328 | No |
| 12 | PRMT3 | PRMT3 Entrez, Source | protein arginine methyltransferase 3 | 4207 | 0.034 | 0.3877 | No |
| 13 | HSD17B12 | HSD17B12 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 12 | 4319 | 0.032 | 0.3947 | No |
| 14 | CARM1 | CARM1 Entrez, Source | coactivator-associated arginine methyltransferase 1 | 5136 | 0.022 | 0.3440 | No |
| 15 | HSD11B2 | HSD11B2 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 2 | 5960 | 0.013 | 0.2884 | No |
| 16 | PRMT2 | PRMT2 Entrez, Source | protein arginine methyltransferase 2 | 7736 | -0.006 | 0.1581 | No |
| 17 | LCMT1 | LCMT1 Entrez, Source | leucine carboxyl methyltransferase 1 | 8072 | -0.010 | 0.1378 | No |
| 18 | LCMT2 | LCMT2 Entrez, Source | leucine carboxyl methyltransferase 2 | 8774 | -0.019 | 0.0941 | No |
| 19 | METTL6 | METTL6 Entrez, Source | methyltransferase like 6 | 9390 | -0.027 | 0.0609 | No |
| 20 | STS | STS Entrez, Source | steroid sulfatase (microsomal), arylsulfatase C, isozyme S | 9956 | -0.036 | 0.0354 | No |
| 21 | HSD17B8 | HSD17B8 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 8 | 10547 | -0.046 | 0.0130 | No |
| 22 | CYP11B1 | CYP11B1 Entrez, Source | cytochrome P450, family 11, subfamily B, polypeptide 1 | 10762 | -0.051 | 0.0210 | No |
| 23 | SRD5A1 | SRD5A1 Entrez, Source | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | 12386 | -0.110 | -0.0488 | No |
| 24 | ARSE | ARSE Entrez, Source | arylsulfatase E (chondrodysplasia punctata 1) | 12562 | -0.122 | -0.0040 | No |
| 25 | HSD17B2 | HSD17B2 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 2 | 12678 | -0.132 | 0.0499 | No |
