Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | HSA00330_ARGININE_AND_PROLINE_METABOLISM |
| Enrichment Score (ES) | 0.4777514 |
| Normalized Enrichment Score (NES) | 1.4306127 |
| Nominal p-value | 0.061503418 |
| FDR q-value | 0.18895012 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ARG1 | ARG1 Entrez, Source | arginase, liver | 117 | 0.209 | 0.1045 | Yes |
| 2 | OTC | OTC Entrez, Source | ornithine carbamoyltransferase | 183 | 0.178 | 0.1960 | Yes |
| 3 | GOT1 | GOT1 Entrez, Source | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 197 | 0.173 | 0.2892 | Yes |
| 4 | CPS1 | CPS1 Entrez, Source | carbamoyl-phosphate synthetase 1, mitochondrial | 236 | 0.162 | 0.3744 | Yes |
| 5 | ASL | ASL Entrez, Source | argininosuccinate lyase | 273 | 0.154 | 0.4554 | Yes |
| 6 | GAMT | GAMT Entrez, Source | guanidinoacetate N-methyltransferase | 910 | 0.102 | 0.4631 | Yes |
| 7 | CKMT1A | CKMT1A Entrez, Source | creatine kinase, mitochondrial 1A | 1842 | 0.071 | 0.4318 | Yes |
| 8 | EPRS | EPRS Entrez, Source | glutamyl-prolyl-tRNA synthetase | 2076 | 0.066 | 0.4504 | Yes |
| 9 | NOS3 | NOS3 Entrez, Source | nitric oxide synthase 3 (endothelial cell) | 2292 | 0.062 | 0.4681 | Yes |
| 10 | PYCRL | PYCRL Entrez, Source | pyrroline-5-carboxylate reductase-like | 2970 | 0.050 | 0.4446 | Yes |
| 11 | ASS1 | ASS1 Entrez, Source | argininosuccinate synthetase 1 | 3063 | 0.049 | 0.4644 | Yes |
| 12 | NOS1 | NOS1 Entrez, Source | nitric oxide synthase 1 (neuronal) | 3225 | 0.047 | 0.4778 | Yes |
| 13 | LAP3 | LAP3 Entrez, Source | leucine aminopeptidase 3 | 3603 | 0.042 | 0.4721 | No |
| 14 | PRODH | PRODH Entrez, Source | proline dehydrogenase (oxidase) 1 | 4210 | 0.034 | 0.4448 | No |
| 15 | GATM | GATM Entrez, Source | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 4229 | 0.033 | 0.4616 | No |
| 16 | CKM | CKM Entrez, Source | creatine kinase, muscle | 5748 | 0.015 | 0.3560 | No |
| 17 | GOT2 | GOT2 Entrez, Source | glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) | 6812 | 0.004 | 0.2784 | No |
| 18 | OAT | OAT Entrez, Source | ornithine aminotransferase (gyrate atrophy) | 8046 | -0.010 | 0.1913 | No |
| 19 | GLUD1 | GLUD1 Entrez, Source | glutamate dehydrogenase 1 | 8367 | -0.014 | 0.1747 | No |
| 20 | CKB | CKB Entrez, Source | creatine kinase, brain | 9906 | -0.035 | 0.0782 | No |
| 21 | ARG2 | ARG2 Entrez, Source | arginase, type II | 12097 | -0.091 | -0.0366 | No |
| 22 | PYCR2 | PYCR2 Entrez, Source | pyrroline-5-carboxylate reductase family, member 2 | 12132 | -0.093 | 0.0114 | No |
| 23 | P4HA1 | P4HA1 Entrez, Source | procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide I | 12791 | -0.146 | 0.0414 | No |
