Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | HSA04110_CELL_CYCLE |
| Enrichment Score (ES) | -0.5961652 |
| Normalized Enrichment Score (NES) | -2.0650415 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.004493233 |
| FWER p-Value | 0.08 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GADD45G | GADD45G Entrez, Source | growth arrest and DNA-damage-inducible, gamma | 160 | 0.189 | 0.0270 | No |
| 2 | CDC26 | CDC26 Entrez, Source | cell division cycle 26 | 1819 | 0.072 | -0.0832 | No |
| 3 | RBL2 | RBL2 Entrez, Source | retinoblastoma-like 2 (p130) | 3391 | 0.045 | -0.1923 | No |
| 4 | CCNH | CCNH Entrez, Source | cyclin H | 4088 | 0.035 | -0.2375 | No |
| 5 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 4258 | 0.033 | -0.2434 | No |
| 6 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 4860 | 0.026 | -0.2834 | No |
| 7 | CDKN1C | CDKN1C Entrez, Source | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 5020 | 0.024 | -0.2906 | No |
| 8 | MAD2L2 | MAD2L2 Entrez, Source | MAD2 mitotic arrest deficient-like 2 (yeast) | 5148 | 0.022 | -0.2956 | No |
| 9 | GADD45A | GADD45A Entrez, Source | growth arrest and DNA-damage-inducible, alpha | 5178 | 0.022 | -0.2933 | No |
| 10 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 5353 | 0.020 | -0.3023 | No |
| 11 | CCNE1 | CCNE1 Entrez, Source | cyclin E1 | 5568 | 0.017 | -0.3149 | No |
| 12 | CCND2 | CCND2 Entrez, Source | cyclin D2 | 5771 | 0.015 | -0.3269 | No |
| 13 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 5802 | 0.015 | -0.3261 | No |
| 14 | ORC2L | ORC2L Entrez, Source | origin recognition complex, subunit 2-like (yeast) | 6017 | 0.013 | -0.3396 | No |
| 15 | CCNA1 | CCNA1 Entrez, Source | cyclin A1 | 6019 | 0.013 | -0.3371 | No |
| 16 | CREBBP | CREBBP Entrez, Source | CREB binding protein (Rubinstein-Taybi syndrome) | 6449 | 0.008 | -0.3678 | No |
| 17 | BUB3 | BUB3 Entrez, Source | BUB3 budding uninhibited by benzimidazoles 3 homolog (yeast) | 6706 | 0.005 | -0.3860 | No |
| 18 | CDC20 | CDC20 Entrez, Source | CDC20 cell division cycle 20 homolog (S. cerevisiae) | 6894 | 0.003 | -0.3994 | No |
| 19 | YWHAE | YWHAE Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide | 6904 | 0.003 | -0.3995 | No |
| 20 | TGFB1 | TGFB1 Entrez, Source | transforming growth factor, beta 1 (Camurati-Engelmann disease) | 7053 | 0.001 | -0.4104 | No |
| 21 | CDKN2C | CDKN2C Entrez, Source | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 7160 | 0.000 | -0.4183 | No |
| 22 | CDK2 | CDK2 Entrez, Source | cyclin-dependent kinase 2 | 7469 | -0.003 | -0.4408 | No |
| 23 | PLK1 | PLK1 Entrez, Source | polo-like kinase 1 (Drosophila) | 7563 | -0.004 | -0.4469 | No |
| 24 | RBX1 | RBX1 Entrez, Source | ring-box 1 | 7789 | -0.007 | -0.4624 | No |
| 25 | HDAC2 | HDAC2 Entrez, Source | histone deacetylase 2 | 8020 | -0.010 | -0.4777 | No |
| 26 | CDC16 | CDC16 Entrez, Source | CDC16 cell division cycle 16 homolog (S. cerevisiae) | 8030 | -0.010 | -0.4764 | No |
| 27 | ORC4L | ORC4L Entrez, Source | origin recognition complex, subunit 4-like (yeast) | 8232 | -0.012 | -0.4890 | No |
| 28 | CDK6 | CDK6 Entrez, Source | cyclin-dependent kinase 6 | 8604 | -0.017 | -0.5135 | No |
| 29 | EP300 | EP300 Entrez, Source | E1A binding protein p300 | 8639 | -0.017 | -0.5124 | No |
| 30 | CDK7 | CDK7 Entrez, Source | cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase) | 9024 | -0.022 | -0.5368 | No |
| 31 | SMC1A | SMC1A Entrez, Source | structural maintenance of chromosomes 1A | 9111 | -0.023 | -0.5385 | No |
| 32 | YWHAG | YWHAG Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide | 9159 | -0.024 | -0.5371 | No |
| 33 | ANAPC4 | ANAPC4 Entrez, Source | anaphase promoting complex subunit 4 | 9241 | -0.025 | -0.5380 | No |
| 34 | ORC3L | ORC3L Entrez, Source | origin recognition complex, subunit 3-like (yeast) | 9431 | -0.028 | -0.5465 | No |
| 35 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 9613 | -0.031 | -0.5538 | No |
| 36 | YWHAB | YWHAB Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide | 9932 | -0.035 | -0.5705 | No |
| 37 | CHEK2 | CHEK2 Entrez, Source | CHK2 checkpoint homolog (S. pombe) | 10020 | -0.037 | -0.5695 | No |
| 38 | YWHAZ | YWHAZ Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 10313 | -0.042 | -0.5829 | No |
| 39 | SMAD4 | SMAD4 Entrez, Source | SMAD, mothers against DPP homolog 4 (Drosophila) | 10473 | -0.045 | -0.5856 | No |
| 40 | GADD45B | GADD45B Entrez, Source | growth arrest and DNA-damage-inducible, beta | 10614 | -0.047 | -0.5864 | Yes |
| 41 | CDC25B | CDC25B Entrez, Source | cell division cycle 25B | 10619 | -0.047 | -0.5770 | Yes |
| 42 | PTTG1 | PTTG1 Entrez, Source | pituitary tumor-transforming 1 | 10625 | -0.047 | -0.5676 | Yes |
| 43 | ORC6L | ORC6L Entrez, Source | origin recognition complex, subunit 6 like (yeast) | 10702 | -0.049 | -0.5631 | Yes |
| 44 | CDC27 | CDC27 Entrez, Source | cell division cycle 27 | 10979 | -0.055 | -0.5725 | Yes |
| 45 | YWHAH | YWHAH Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide | 11003 | -0.056 | -0.5627 | Yes |
| 46 | CDKN2B | CDKN2B Entrez, Source | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) | 11022 | -0.056 | -0.5524 | Yes |
| 47 | SMAD3 | SMAD3 Entrez, Source | SMAD, mothers against DPP homolog 3 (Drosophila) | 11131 | -0.059 | -0.5485 | Yes |
| 48 | SMAD2 | SMAD2 Entrez, Source | SMAD, mothers against DPP homolog 2 (Drosophila) | 11223 | -0.061 | -0.5428 | Yes |
| 49 | BUB1B | BUB1B Entrez, Source | BUB1 budding uninhibited by benzimidazoles 1 homolog beta (yeast) | 11337 | -0.063 | -0.5383 | Yes |
| 50 | RB1 | RB1 Entrez, Source | retinoblastoma 1 (including osteosarcoma) | 11401 | -0.065 | -0.5296 | Yes |
| 51 | CDKN1B | CDKN1B Entrez, Source | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 11651 | -0.074 | -0.5331 | Yes |
| 52 | GSK3B | GSK3B Entrez, Source | glycogen synthase kinase 3 beta | 11670 | -0.074 | -0.5191 | Yes |
| 53 | CCND3 | CCND3 Entrez, Source | cyclin D3 | 11760 | -0.077 | -0.5099 | Yes |
| 54 | ORC1L | ORC1L Entrez, Source | origin recognition complex, subunit 1-like (yeast) | 11803 | -0.079 | -0.4967 | Yes |
| 55 | CDKN2D | CDKN2D Entrez, Source | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) | 11809 | -0.080 | -0.4806 | Yes |
| 56 | CDC23 | CDC23 Entrez, Source | CDC23 (cell division cycle 23, yeast, homolog) | 11864 | -0.082 | -0.4679 | Yes |
| 57 | CDKN2A | CDKN2A Entrez, Source | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 12064 | -0.090 | -0.4644 | Yes |
| 58 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 12106 | -0.092 | -0.4486 | Yes |
| 59 | CDK4 | CDK4 Entrez, Source | cyclin-dependent kinase 4 | 12294 | -0.103 | -0.4414 | Yes |
| 60 | ANAPC2 | ANAPC2 Entrez, Source | anaphase promoting complex subunit 2 | 12308 | -0.104 | -0.4210 | Yes |
| 61 | CCNB2 | CCNB2 Entrez, Source | cyclin B2 | 12396 | -0.111 | -0.4047 | Yes |
| 62 | YWHAQ | YWHAQ Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide | 12415 | -0.112 | -0.3830 | Yes |
| 63 | WEE1 | WEE1 Entrez, Source | WEE1 homolog (S. pombe) | 12774 | -0.145 | -0.3802 | Yes |
| 64 | CHEK1 | CHEK1 Entrez, Source | CHK1 checkpoint homolog (S. pombe) | 12915 | -0.168 | -0.3560 | Yes |
| 65 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 13022 | -0.195 | -0.3237 | Yes |
| 66 | CCNB1 | CCNB1 Entrez, Source | cyclin B1 | 13126 | -0.245 | -0.2810 | Yes |
| 67 | TGFB3 | TGFB3 Entrez, Source | transforming growth factor, beta 3 | 13142 | -0.253 | -0.2300 | Yes |
| 68 | CCND1 | CCND1 Entrez, Source | cyclin D1 | 13250 | -0.352 | -0.1656 | Yes |
| 69 | CCNA2 | CCNA2 Entrez, Source | cyclin A2 | 13257 | -0.367 | -0.0904 | Yes |
| 70 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13301 | -0.469 | 0.0031 | Yes |
