Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | HSA04520_ADHERENS_JUNCTION |
| Enrichment Score (ES) | -0.5489237 |
| Normalized Enrichment Score (NES) | -1.7520831 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.049866058 |
| FWER p-Value | 0.998 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | INSR | INSR Entrez, Source | insulin receptor | 772 | 0.108 | -0.0286 | No |
| 2 | FGFR1 | FGFR1 Entrez, Source | fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome) | 873 | 0.104 | -0.0077 | No |
| 3 | SNAI1 | SNAI1 Entrez, Source | snail homolog 1 (Drosophila) | 1586 | 0.077 | -0.0400 | No |
| 4 | FYN | FYN Entrez, Source | FYN oncogene related to SRC, FGR, YES | 1682 | 0.075 | -0.0268 | No |
| 5 | PVRL1 | PVRL1 Entrez, Source | poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin) | 1799 | 0.072 | -0.0158 | No |
| 6 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 2688 | 0.055 | -0.0674 | No |
| 7 | PTPN6 | PTPN6 Entrez, Source | protein tyrosine phosphatase, non-receptor type 6 | 3190 | 0.047 | -0.0921 | No |
| 8 | SRC | SRC Entrez, Source | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 3918 | 0.038 | -0.1365 | No |
| 9 | ACP1 | ACP1 Entrez, Source | acid phosphatase 1, soluble | 4064 | 0.035 | -0.1377 | No |
| 10 | LEF1 | LEF1 Entrez, Source | lymphoid enhancer-binding factor 1 | 4464 | 0.030 | -0.1594 | No |
| 11 | IGF1R | IGF1R Entrez, Source | insulin-like growth factor 1 receptor | 4743 | 0.027 | -0.1729 | No |
| 12 | PARD3 | PARD3 Entrez, Source | par-3 partitioning defective 3 homolog (C. elegans) | 5990 | 0.013 | -0.2632 | No |
| 13 | CDH1 | CDH1 Entrez, Source | cadherin 1, type 1, E-cadherin (epithelial) | 6086 | 0.012 | -0.2670 | No |
| 14 | RAC2 | RAC2 Entrez, Source | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) | 6150 | 0.011 | -0.2686 | No |
| 15 | TGFBR1 | TGFBR1 Entrez, Source | transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa) | 6257 | 0.010 | -0.2738 | No |
| 16 | CREBBP | CREBBP Entrez, Source | CREB binding protein (Rubinstein-Taybi syndrome) | 6449 | 0.008 | -0.2860 | No |
| 17 | MAPK1 | MAPK1 Entrez, Source | mitogen-activated protein kinase 1 | 6633 | 0.006 | -0.2981 | No |
| 18 | PTPRJ | PTPRJ Entrez, Source | protein tyrosine phosphatase, receptor type, J | 6741 | 0.005 | -0.3048 | No |
| 19 | SSX2IP | SSX2IP Entrez, Source | synovial sarcoma, X breakpoint 2 interacting protein | 6954 | 0.002 | -0.3200 | No |
| 20 | CSNK2A1 | CSNK2A1 Entrez, Source | casein kinase 2, alpha 1 polypeptide | 6997 | 0.002 | -0.3227 | No |
| 21 | CSNK2B | CSNK2B Entrez, Source | casein kinase 2, beta polypeptide | 7077 | 0.001 | -0.3283 | No |
| 22 | EP300 | EP300 Entrez, Source | E1A binding protein p300 | 8639 | -0.017 | -0.4410 | No |
| 23 | CTNNB1 | CTNNB1 Entrez, Source | catenin (cadherin-associated protein), beta 1, 88kDa | 8921 | -0.021 | -0.4564 | No |
| 24 | PTPRM | PTPRM Entrez, Source | protein tyrosine phosphatase, receptor type, M | 8923 | -0.021 | -0.4508 | No |
| 25 | ACVR1C | ACVR1C Entrez, Source | activin A receptor, type IC | 9381 | -0.027 | -0.4777 | No |
| 26 | MLLT4 | MLLT4 Entrez, Source | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 | 10164 | -0.039 | -0.5258 | No |
| 27 | SMAD4 | SMAD4 Entrez, Source | SMAD, mothers against DPP homolog 4 (Drosophila) | 10473 | -0.045 | -0.5367 | Yes |
| 28 | RHOA | RHOA Entrez, Source | ras homolog gene family, member A | 10584 | -0.047 | -0.5322 | Yes |
| 29 | CDC42 | CDC42 Entrez, Source | cell division cycle 42 (GTP binding protein, 25kDa) | 10703 | -0.049 | -0.5275 | Yes |
| 30 | ERBB2 | ERBB2 Entrez, Source | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 10906 | -0.054 | -0.5280 | Yes |
| 31 | RAC1 | RAC1 Entrez, Source | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 10939 | -0.055 | -0.5155 | Yes |
| 32 | SMAD3 | SMAD3 Entrez, Source | SMAD, mothers against DPP homolog 3 (Drosophila) | 11131 | -0.059 | -0.5138 | Yes |
| 33 | WASF2 | WASF2 Entrez, Source | WAS protein family, member 2 | 11151 | -0.059 | -0.4990 | Yes |
| 34 | SMAD2 | SMAD2 Entrez, Source | SMAD, mothers against DPP homolog 2 (Drosophila) | 11223 | -0.061 | -0.4877 | Yes |
| 35 | ACTB | ACTB Entrez, Source | actin, beta | 11264 | -0.061 | -0.4739 | Yes |
| 36 | WASL | WASL Entrez, Source | Wiskott-Aldrich syndrome-like | 11892 | -0.083 | -0.4984 | Yes |
| 37 | WASF1 | WASF1 Entrez, Source | WAS protein family, member 1 | 11932 | -0.084 | -0.4783 | Yes |
| 38 | TGFBR2 | TGFBR2 Entrez, Source | transforming growth factor, beta receptor II (70/80kDa) | 12175 | -0.096 | -0.4703 | Yes |
| 39 | BAIAP2 | BAIAP2 Entrez, Source | BAI1-associated protein 2 | 12628 | -0.128 | -0.4694 | Yes |
| 40 | MET | MET Entrez, Source | met proto-oncogene (hepatocyte growth factor receptor) | 12631 | -0.128 | -0.4346 | Yes |
| 41 | MAPK3 | MAPK3 Entrez, Source | mitogen-activated protein kinase 3 | 12674 | -0.132 | -0.4017 | Yes |
| 42 | PTPRF | PTPRF Entrez, Source | protein tyrosine phosphatase, receptor type, F | 12684 | -0.133 | -0.3660 | Yes |
| 43 | PTPN1 | PTPN1 Entrez, Source | protein tyrosine phosphatase, non-receptor type 1 | 12685 | -0.133 | -0.3295 | Yes |
| 44 | ACTN4 | ACTN4 Entrez, Source | actinin, alpha 4 | 12842 | -0.155 | -0.2989 | Yes |
| 45 | ACTN3 | ACTN3 Entrez, Source | actinin, alpha 3 | 13042 | -0.204 | -0.2580 | Yes |
| 46 | LMO7 | LMO7 Entrez, Source | LIM domain 7 | 13174 | -0.275 | -0.1926 | Yes |
| 47 | PVRL2 | PVRL2 Entrez, Source | poliovirus receptor-related 2 (herpesvirus entry mediator B) | 13177 | -0.277 | -0.1169 | Yes |
| 48 | ACTN1 | ACTN1 Entrez, Source | actinin, alpha 1 | 13303 | -0.473 | 0.0029 | Yes |
