Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | HYPOPHYSECTOMY_RAT_DN |
| Enrichment Score (ES) | 0.5358166 |
| Normalized Enrichment Score (NES) | 1.8545358 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.022414904 |
| FWER p-Value | 0.735 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FBP1 | FBP1 Entrez, Source | fructose-1,6-bisphosphatase 1 | 67 | 0.255 | 0.0960 | Yes |
| 2 | ACAA2 | ACAA2 Entrez, Source | acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase) | 163 | 0.187 | 0.1630 | Yes |
| 3 | FDPS | FDPS Entrez, Source | farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase) | 171 | 0.184 | 0.2352 | Yes |
| 4 | PDK4 | PDK4 Entrez, Source | pyruvate dehydrogenase kinase, isozyme 4 | 207 | 0.172 | 0.3004 | Yes |
| 5 | ALAS1 | ALAS1 Entrez, Source | aminolevulinate, delta-, synthase 1 | 300 | 0.149 | 0.3527 | Yes |
| 6 | CYB5B | CYB5B Entrez, Source | cytochrome b5 type B (outer mitochondrial membrane) | 498 | 0.125 | 0.3874 | Yes |
| 7 | ACSL1 | ACSL1 Entrez, Source | acyl-CoA synthetase long-chain family member 1 | 564 | 0.121 | 0.4302 | Yes |
| 8 | AQP8 | AQP8 Entrez, Source | aquaporin 8 | 728 | 0.110 | 0.4615 | Yes |
| 9 | CALR | CALR Entrez, Source | calreticulin | 768 | 0.108 | 0.5014 | Yes |
| 10 | ALDOB | ALDOB Entrez, Source | aldolase B, fructose-bisphosphate | 941 | 0.100 | 0.5279 | Yes |
| 11 | PEX19 | PEX19 Entrez, Source | peroxisomal biogenesis factor 19 | 1291 | 0.086 | 0.5358 | Yes |
| 12 | PADI4 | PADI4 Entrez, Source | peptidyl arginine deiminase, type IV | 2211 | 0.064 | 0.4919 | No |
| 13 | PIM3 | PIM3 Entrez, Source | pim-3 oncogene | 2235 | 0.063 | 0.5153 | No |
| 14 | MGP | MGP Entrez, Source | matrix Gla protein | 2580 | 0.057 | 0.5120 | No |
| 15 | SPARC | SPARC Entrez, Source | secreted protein, acidic, cysteine-rich (osteonectin) | 2588 | 0.057 | 0.5341 | No |
| 16 | NPPA | NPPA Entrez, Source | natriuretic peptide precursor A | 3492 | 0.043 | 0.4832 | No |
| 17 | SCD | SCD Entrez, Source | stearoyl-CoA desaturase (delta-9-desaturase) | 3852 | 0.039 | 0.4715 | No |
| 18 | IDH1 | IDH1 Entrez, Source | isocitrate dehydrogenase 1 (NADP+), soluble | 3953 | 0.037 | 0.4787 | No |
| 19 | DDC | DDC Entrez, Source | dopa decarboxylase (aromatic L-amino acid decarboxylase) | 4512 | 0.030 | 0.4486 | No |
| 20 | PDIA3 | PDIA3 Entrez, Source | protein disulfide isomerase family A, member 3 | 5084 | 0.023 | 0.4146 | No |
| 21 | TKT | TKT Entrez, Source | transketolase (Wernicke-Korsakoff syndrome) | 5330 | 0.020 | 0.4042 | No |
| 22 | FTH1 | FTH1 Entrez, Source | ferritin, heavy polypeptide 1 | 6227 | 0.011 | 0.3410 | No |
| 23 | COL3A1 | COL3A1 Entrez, Source | collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) | 6389 | 0.009 | 0.3323 | No |
| 24 | AHSG | AHSG Entrez, Source | alpha-2-HS-glycoprotein | 6652 | 0.006 | 0.3149 | No |
| 25 | DECR1 | DECR1 Entrez, Source | 2,4-dienoyl CoA reductase 1, mitochondrial | 6746 | 0.005 | 0.3098 | No |
| 26 | FBLN5 | FBLN5 Entrez, Source | fibulin 5 | 6865 | 0.003 | 0.3023 | No |
| 27 | AKR1A1 | AKR1A1 Entrez, Source | aldo-keto reductase family 1, member A1 (aldehyde reductase) | 6869 | 0.003 | 0.3035 | No |
| 28 | FN1 | FN1 Entrez, Source | fibronectin 1 | 7215 | -0.000 | 0.2777 | No |
| 29 | SLC9A1 | SLC9A1 Entrez, Source | solute carrier family 9 (sodium/hydrogen exchanger), member 1 (antiporter, Na+/H+, amiloride sensitive) | 7242 | -0.001 | 0.2760 | No |
| 30 | TFF3 | TFF3 Entrez, Source | trefoil factor 3 (intestinal) | 7322 | -0.002 | 0.2707 | No |
| 31 | ODC1 | ODC1 Entrez, Source | ornithine decarboxylase 1 | 7596 | -0.005 | 0.2521 | No |
| 32 | LIMS2 | LIMS2 Entrez, Source | LIM and senescent cell antigen-like domains 2 | 7699 | -0.006 | 0.2467 | No |
| 33 | HADH | HADH Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase | 7824 | -0.007 | 0.2403 | No |
| 34 | OAT | OAT Entrez, Source | ornithine aminotransferase (gyrate atrophy) | 8046 | -0.010 | 0.2276 | No |
| 35 | ECH1 | ECH1 Entrez, Source | enoyl Coenzyme A hydratase 1, peroxisomal | 8150 | -0.011 | 0.2243 | No |
| 36 | LDHA | LDHA Entrez, Source | lactate dehydrogenase A | 8185 | -0.012 | 0.2264 | No |
| 37 | GLUD1 | GLUD1 Entrez, Source | glutamate dehydrogenase 1 | 8367 | -0.014 | 0.2182 | No |
| 38 | MEP1B | MEP1B Entrez, Source | meprin A, beta | 8605 | -0.017 | 0.2071 | No |
| 39 | DAD1 | DAD1 Entrez, Source | defender against cell death 1 | 8855 | -0.020 | 0.1962 | No |
| 40 | B2M | B2M Entrez, Source | beta-2-microglobulin | 9260 | -0.025 | 0.1759 | No |
| 41 | ARF4 | ARF4 Entrez, Source | ADP-ribosylation factor 4 | 9461 | -0.028 | 0.1721 | No |
| 42 | ATP2A2 | ATP2A2 Entrez, Source | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 9652 | -0.031 | 0.1702 | No |
| 43 | RAB3B | RAB3B Entrez, Source | RAB3B, member RAS oncogene family | 9706 | -0.032 | 0.1789 | No |
| 44 | PSMB8 | PSMB8 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) | 10918 | -0.054 | 0.1093 | No |
| 45 | DCN | DCN Entrez, Source | decorin | 11977 | -0.086 | 0.0637 | No |
| 46 | PPGB | PPGB Entrez, Source | protective protein for beta-galactosidase (galactosialidosis) | 12222 | -0.098 | 0.0842 | No |
