Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | HYPOXIA_REG_UP |
| Enrichment Score (ES) | -0.680595 |
| Normalized Enrichment Score (NES) | -2.0079882 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0070900815 |
| FWER p-Value | 0.201 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PPP1R3C | PPP1R3C Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 3C | 40 | 0.295 | 0.0595 | No |
| 2 | DDIT4 | DDIT4 Entrez, Source | DNA-damage-inducible transcript 4 | 134 | 0.198 | 0.0946 | No |
| 3 | BHLHB2 | BHLHB2 Entrez, Source | basic helix-loop-helix domain containing, class B, 2 | 766 | 0.108 | 0.0701 | No |
| 4 | VEGF | VEGF Entrez, Source | vascular endothelial growth factor | 1883 | 0.070 | 0.0012 | No |
| 5 | STC2 | STC2 Entrez, Source | stanniocalcin 2 | 2017 | 0.068 | 0.0055 | No |
| 6 | JUNB | JUNB Entrez, Source | jun B proto-oncogene | 2033 | 0.067 | 0.0186 | No |
| 7 | SLC7A5 | SLC7A5 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 | 2396 | 0.060 | 0.0042 | No |
| 8 | NFIL3 | NFIL3 Entrez, Source | nuclear factor, interleukin 3 regulated | 2690 | 0.055 | -0.0061 | No |
| 9 | HNRPA1 | HNRPA1 Entrez, Source | heterogeneous nuclear ribonucleoprotein A1 | 2977 | 0.050 | -0.0169 | No |
| 10 | TGFA | TGFA Entrez, Source | transforming growth factor, alpha | 4483 | 0.030 | -0.1235 | No |
| 11 | RASGRP1 | RASGRP1 Entrez, Source | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | 4950 | 0.024 | -0.1534 | No |
| 12 | PFKFB4 | PFKFB4 Entrez, Source | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 5052 | 0.023 | -0.1560 | No |
| 13 | DUSP1 | DUSP1 Entrez, Source | dual specificity phosphatase 1 | 5117 | 0.022 | -0.1561 | No |
| 14 | PTDSR | PTDSR Entrez, Source | phosphatidylserine receptor | 5310 | 0.020 | -0.1662 | No |
| 15 | ADFP | ADFP Entrez, Source | adipose differentiation-related protein | 5942 | 0.013 | -0.2108 | No |
| 16 | MUC1 | MUC1 Entrez, Source | mucin 1, cell surface associated | 6417 | 0.008 | -0.2446 | No |
| 17 | EFNA1 | EFNA1 Entrez, Source | ephrin-A1 | 7146 | 0.000 | -0.2992 | No |
| 18 | FUS | FUS Entrez, Source | fusion (involved in t(12;16) in malignant liposarcoma) | 8068 | -0.010 | -0.3662 | No |
| 19 | BNIP3 | BNIP3 Entrez, Source | BCL2/adenovirus E1B 19kDa interacting protein 3 | 8690 | -0.018 | -0.4091 | No |
| 20 | PGK1 | PGK1 Entrez, Source | phosphoglycerate kinase 1 | 9333 | -0.026 | -0.4517 | No |
| 21 | CDKN1B | CDKN1B Entrez, Source | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 11651 | -0.074 | -0.6101 | No |
| 22 | ALDOA | ALDOA Entrez, Source | aldolase A, fructose-bisphosphate | 11945 | -0.085 | -0.6141 | No |
| 23 | PHC2 | PHC2 Entrez, Source | polyhomeotic homolog 2 (Drosophila) | 12831 | -0.153 | -0.6482 | Yes |
| 24 | SLC2A1 | SLC2A1 Entrez, Source | solute carrier family 2 (facilitated glucose transporter), member 1 | 13210 | -0.303 | -0.6124 | Yes |
| 25 | SLC16A3 | SLC16A3 Entrez, Source | solute carrier family 16, member 3 (monocarboxylic acid transporter 4) | 13219 | -0.314 | -0.5464 | Yes |
| 26 | ADORA2B | ADORA2B Entrez, Source | adenosine A2b receptor | 13236 | -0.333 | -0.4770 | Yes |
| 27 | GPRC5A | GPRC5A Entrez, Source | G protein-coupled receptor, family C, group 5, member A | 13268 | -0.382 | -0.3984 | Yes |
| 28 | ADM | ADM Entrez, Source | adrenomedullin | 13274 | -0.393 | -0.3154 | Yes |
| 29 | SERPINE1 | SERPINE1 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 13308 | -0.484 | -0.2153 | Yes |
| 30 | F3 | F3 Entrez, Source | coagulation factor III (thromboplastin, tissue factor) | 13315 | -0.511 | -0.1074 | Yes |
| 31 | PFKP | PFKP Entrez, Source | phosphofructokinase, platelet | 13318 | -0.516 | 0.0018 | Yes |
