Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | IDX_TSA_DN_CLUSTER3 |
| Enrichment Score (ES) | -0.57132256 |
| Normalized Enrichment Score (NES) | -1.9145873 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.021052953 |
| FWER p-Value | 0.574 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | VCAM1 | VCAM1 Entrez, Source | vascular cell adhesion molecule 1 | 213 | 0.170 | 0.0145 | No |
| 2 | CXCL12 | CXCL12 Entrez, Source | chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) | 295 | 0.150 | 0.0354 | No |
| 3 | GPC4 | GPC4 Entrez, Source | glypican 4 | 372 | 0.139 | 0.0546 | No |
| 4 | PTGS2 | PTGS2 Entrez, Source | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 886 | 0.103 | 0.0345 | No |
| 5 | FADS1 | FADS1 Entrez, Source | fatty acid desaturase 1 | 1932 | 0.070 | -0.0316 | No |
| 6 | GSTT1 | GSTT1 Entrez, Source | glutathione S-transferase theta 1 | 1944 | 0.069 | -0.0200 | No |
| 7 | NDRG4 | NDRG4 Entrez, Source | NDRG family member 4 | 2272 | 0.063 | -0.0333 | No |
| 8 | TSPYL4 | TSPYL4 Entrez, Source | TSPY-like 4 | 2308 | 0.062 | -0.0249 | No |
| 9 | SPP1 | SPP1 Entrez, Source | secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) | 2593 | 0.057 | -0.0360 | No |
| 10 | PHLDA1 | PHLDA1 Entrez, Source | pleckstrin homology-like domain, family A, member 1 | 2920 | 0.051 | -0.0513 | No |
| 11 | CEBPD | CEBPD Entrez, Source | CCAAT/enhancer binding protein (C/EBP), delta | 4223 | 0.034 | -0.1433 | No |
| 12 | PLA2G4A | PLA2G4A Entrez, Source | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 4307 | 0.033 | -0.1437 | No |
| 13 | THBS2 | THBS2 Entrez, Source | thrombospondin 2 | 4709 | 0.027 | -0.1689 | No |
| 14 | MAOA | MAOA Entrez, Source | monoamine oxidase A | 5177 | 0.022 | -0.2002 | No |
| 15 | CSF1 | CSF1 Entrez, Source | colony stimulating factor 1 (macrophage) | 5308 | 0.020 | -0.2063 | No |
| 16 | CCT3 | CCT3 Entrez, Source | chaperonin containing TCP1, subunit 3 (gamma) | 5954 | 0.013 | -0.2525 | No |
| 17 | DNM1 | DNM1 Entrez, Source | dynamin 1 | 6060 | 0.012 | -0.2582 | No |
| 18 | PLK2 | PLK2 Entrez, Source | polo-like kinase 2 (Drosophila) | 6290 | 0.010 | -0.2737 | No |
| 19 | GGTA1 | GGTA1 Entrez, Source | glycoprotein, alpha-galactosyltransferase 1 | 6325 | 0.009 | -0.2745 | No |
| 20 | AKAP12 | AKAP12 Entrez, Source | A kinase (PRKA) anchor protein (gravin) 12 | 6511 | 0.007 | -0.2871 | No |
| 21 | SLC8A1 | SLC8A1 Entrez, Source | solute carrier family 8 (sodium/calcium exchanger), member 1 | 7943 | -0.009 | -0.3933 | No |
| 22 | EPHX1 | EPHX1 Entrez, Source | epoxide hydrolase 1, microsomal (xenobiotic) | 8371 | -0.014 | -0.4229 | No |
| 23 | ACVR2A | ACVR2A Entrez, Source | activin A receptor, type IIA | 8618 | -0.017 | -0.4384 | No |
| 24 | RASSF5 | RASSF5 Entrez, Source | Ras association (RalGDS/AF-6) domain family 5 | 9349 | -0.027 | -0.4885 | No |
| 25 | CNN3 | CNN3 Entrez, Source | calponin 3, acidic | 9383 | -0.027 | -0.4861 | No |
| 26 | SFRP2 | SFRP2 Entrez, Source | secreted frizzled-related protein 2 | 9638 | -0.031 | -0.4997 | No |
| 27 | ARMCX2 | ARMCX2 Entrez, Source | armadillo repeat containing, X-linked 2 | 10401 | -0.044 | -0.5492 | No |
| 28 | IFI30 | IFI30 Entrez, Source | interferon, gamma-inducible protein 30 | 10696 | -0.049 | -0.5625 | Yes |
| 29 | STXBP3 | STXBP3 Entrez, Source | syntaxin binding protein 3 | 10705 | -0.050 | -0.5542 | Yes |
| 30 | JUP | JUP Entrez, Source | junction plakoglobin | 10892 | -0.053 | -0.5586 | Yes |
| 31 | ANXA11 | ANXA11 Entrez, Source | annexin A11 | 10926 | -0.054 | -0.5513 | Yes |
| 32 | CDKN2B | CDKN2B Entrez, Source | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) | 11022 | -0.056 | -0.5483 | Yes |
| 33 | SKAP2 | SKAP2 Entrez, Source | src kinase associated phosphoprotein 2 | 11101 | -0.058 | -0.5438 | Yes |
| 34 | SPG20 | SPG20 Entrez, Source | spastic paraplegia 20, spartin (Troyer syndrome) | 11182 | -0.060 | -0.5390 | Yes |
| 35 | EIF4B | EIF4B Entrez, Source | eukaryotic translation initiation factor 4B | 11325 | -0.063 | -0.5384 | Yes |
| 36 | PSCD3 | PSCD3 Entrez, Source | pleckstrin homology, Sec7 and coiled-coil domains 3 | 11425 | -0.066 | -0.5340 | Yes |
| 37 | NEDD9 | NEDD9 Entrez, Source | neural precursor cell expressed, developmentally down-regulated 9 | 11537 | -0.070 | -0.5298 | Yes |
| 38 | KLF4 | KLF4 Entrez, Source | Kruppel-like factor 4 (gut) | 11554 | -0.070 | -0.5184 | Yes |
| 39 | FZD2 | FZD2 Entrez, Source | frizzled homolog 2 (Drosophila) | 11656 | -0.074 | -0.5127 | Yes |
| 40 | EXOC4 | EXOC4 Entrez, Source | exocyst complex component 4 | 11873 | -0.082 | -0.5142 | Yes |
| 41 | CDKN2A | CDKN2A Entrez, Source | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 12064 | -0.090 | -0.5124 | Yes |
| 42 | CDK4 | CDK4 Entrez, Source | cyclin-dependent kinase 4 | 12294 | -0.103 | -0.5111 | Yes |
| 43 | BCAR1 | BCAR1 Entrez, Source | breast cancer anti-estrogen resistance 1 | 12497 | -0.117 | -0.5052 | Yes |
| 44 | PRKCD | PRKCD Entrez, Source | protein kinase C, delta | 12535 | -0.120 | -0.4864 | Yes |
| 45 | CYR61 | CYR61 Entrez, Source | cysteine-rich, angiogenic inducer, 61 | 12557 | -0.122 | -0.4661 | Yes |
| 46 | ROCK2 | ROCK2 Entrez, Source | Rho-associated, coiled-coil containing protein kinase 2 | 12599 | -0.125 | -0.4467 | Yes |
| 47 | PLEKHC1 | PLEKHC1 Entrez, Source | pleckstrin homology domain containing, family C (with FERM domain) member 1 | 12603 | -0.125 | -0.4244 | Yes |
| 48 | DOK1 | DOK1 Entrez, Source | docking protein 1, 62kDa (downstream of tyrosine kinase 1) | 12620 | -0.127 | -0.4027 | Yes |
| 49 | SIRT2 | SIRT2 Entrez, Source | sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae) | 12702 | -0.135 | -0.3845 | Yes |
| 50 | MAGED2 | MAGED2 Entrez, Source | melanoma antigen family D, 2 | 12723 | -0.137 | -0.3613 | Yes |
| 51 | CSRP1 | CSRP1 Entrez, Source | cysteine and glycine-rich protein 1 | 12832 | -0.153 | -0.3420 | Yes |
| 52 | DDAH2 | DDAH2 Entrez, Source | dimethylarginine dimethylaminohydrolase 2 | 12970 | -0.181 | -0.3198 | Yes |
| 53 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 12980 | -0.185 | -0.2873 | Yes |
| 54 | DPP7 | DPP7 Entrez, Source | dipeptidyl-peptidase 7 | 13151 | -0.257 | -0.2539 | Yes |
| 55 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 13220 | -0.314 | -0.2025 | Yes |
| 56 | CITED2 | CITED2 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 13226 | -0.322 | -0.1450 | Yes |
| 57 | PLAT | PLAT Entrez, Source | plasminogen activator, tissue | 13241 | -0.343 | -0.0844 | Yes |
| 58 | F3 | F3 Entrez, Source | coagulation factor III (thromboplastin, tissue factor) | 13315 | -0.511 | 0.0020 | Yes |
