Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | IGF1PATHWAY |
| Enrichment Score (ES) | 0.61868846 |
| Normalized Enrichment Score (NES) | 1.6925179 |
| Nominal p-value | 0.013157895 |
| FDR q-value | 0.061197944 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FOS | FOS Entrez, Source | v-fos FBJ murine osteosarcoma viral oncogene homolog | 0 | 1.012 | 0.5478 | Yes |
| 2 | IRS1 | IRS1 Entrez, Source | insulin receptor substrate 1 | 233 | 0.163 | 0.6187 | Yes |
| 3 | RAF1 | RAF1 Entrez, Source | v-raf-1 murine leukemia viral oncogene homolog 1 | 2284 | 0.062 | 0.4987 | No |
| 4 | SHC1 | SHC1 Entrez, Source | SHC (Src homology 2 domain containing) transforming protein 1 | 2417 | 0.060 | 0.5213 | No |
| 5 | PIK3R1 | PIK3R1 Entrez, Source | phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha) | 2668 | 0.056 | 0.5328 | No |
| 6 | IGF1 | IGF1 Entrez, Source | insulin-like growth factor 1 (somatomedin C) | 4345 | 0.032 | 0.4244 | No |
| 7 | IGF1R | IGF1R Entrez, Source | insulin-like growth factor 1 receptor | 4743 | 0.027 | 0.4092 | No |
| 8 | CSNK2A1 | CSNK2A1 Entrez, Source | casein kinase 2, alpha 1 polypeptide | 6997 | 0.002 | 0.2412 | No |
| 9 | GRB2 | GRB2 Entrez, Source | growth factor receptor-bound protein 2 | 7179 | 0.000 | 0.2276 | No |
| 10 | PTPN11 | PTPN11 Entrez, Source | protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) | 7325 | -0.002 | 0.2176 | No |
| 11 | RASA1 | RASA1 Entrez, Source | RAS p21 protein activator (GTPase activating protein) 1 | 7619 | -0.005 | 0.1984 | No |
| 12 | JUN | JUN Entrez, Source | jun oncogene | 8081 | -0.010 | 0.1694 | No |
| 13 | MAP2K1 | MAP2K1 Entrez, Source | mitogen-activated protein kinase kinase 1 | 8219 | -0.012 | 0.1656 | No |
| 14 | HRAS | HRAS Entrez, Source | v-Ha-ras Harvey rat sarcoma viral oncogene homolog | 9267 | -0.025 | 0.1008 | No |
| 15 | ELK1 | ELK1 Entrez, Source | ELK1, member of ETS oncogene family | 12262 | -0.100 | -0.0694 | No |
| 16 | MAPK3 | MAPK3 Entrez, Source | mitogen-activated protein kinase 3 | 12674 | -0.132 | -0.0290 | No |
| 17 | PIK3CA | PIK3CA Entrez, Source | phosphoinositide-3-kinase, catalytic, alpha polypeptide | 12788 | -0.146 | 0.0416 | No |
