Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | IGLESIAS_E2FMINUS_UP |
| Enrichment Score (ES) | -0.4958935 |
| Normalized Enrichment Score (NES) | -1.8255371 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.03741575 |
| FWER p-Value | 0.935 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CDO1 | CDO1 Entrez, Source | cysteine dioxygenase, type I | 54 | 0.279 | 0.0278 | No |
| 2 | CTSE | CTSE Entrez, Source | cathepsin E | 170 | 0.184 | 0.0402 | No |
| 3 | IGFBP4 | IGFBP4 Entrez, Source | insulin-like growth factor binding protein 4 | 406 | 0.135 | 0.0379 | No |
| 4 | C1QB | C1QB Entrez, Source | complement component 1, q subcomponent, B chain | 465 | 0.129 | 0.0482 | No |
| 5 | ENPP2 | ENPP2 Entrez, Source | ectonucleotide pyrophosphatase/phosphodiesterase 2 (autotaxin) | 511 | 0.124 | 0.0591 | No |
| 6 | CES3 | CES3 Entrez, Source | carboxylesterase 3 (brain) | 629 | 0.116 | 0.0636 | No |
| 7 | LGALS1 | LGALS1 Entrez, Source | lectin, galactoside-binding, soluble, 1 (galectin 1) | 749 | 0.109 | 0.0671 | No |
| 8 | UGDH | UGDH Entrez, Source | UDP-glucose dehydrogenase | 1562 | 0.078 | 0.0147 | No |
| 9 | CTSS | CTSS Entrez, Source | cathepsin S | 1728 | 0.074 | 0.0106 | No |
| 10 | C3 | C3 Entrez, Source | complement component 3 | 1731 | 0.074 | 0.0189 | No |
| 11 | RHOB | RHOB Entrez, Source | ras homolog gene family, member B | 1840 | 0.071 | 0.0189 | No |
| 12 | COL1A2 | COL1A2 Entrez, Source | collagen, type I, alpha 2 | 2001 | 0.068 | 0.0146 | No |
| 13 | CD53 | CD53 Entrez, Source | CD53 molecule | 2203 | 0.064 | 0.0067 | No |
| 14 | FBLN2 | FBLN2 Entrez, Source | fibulin 2 | 2463 | 0.059 | -0.0060 | No |
| 15 | CFD | CFD Entrez, Source | complement factor D (adipsin) | 2506 | 0.058 | -0.0025 | No |
| 16 | CD9 | CD9 Entrez, Source | CD9 molecule | 2527 | 0.058 | 0.0026 | No |
| 17 | SPARC | SPARC Entrez, Source | secreted protein, acidic, cysteine-rich (osteonectin) | 2588 | 0.057 | 0.0046 | No |
| 18 | IGFBP5 | IGFBP5 Entrez, Source | insulin-like growth factor binding protein 5 | 2629 | 0.056 | 0.0080 | No |
| 19 | COL15A1 | COL15A1 Entrez, Source | collagen, type XV, alpha 1 | 3242 | 0.047 | -0.0329 | No |
| 20 | COL6A2 | COL6A2 Entrez, Source | collagen, type VI, alpha 2 | 3659 | 0.041 | -0.0596 | No |
| 21 | APLP2 | APLP2 Entrez, Source | amyloid beta (A4) precursor-like protein 2 | 3820 | 0.039 | -0.0672 | No |
| 22 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 4258 | 0.033 | -0.0964 | No |
| 23 | COL4A1 | COL4A1 Entrez, Source | collagen, type IV, alpha 1 | 4425 | 0.031 | -0.1054 | No |
| 24 | COL1A1 | COL1A1 Entrez, Source | collagen, type I, alpha 1 | 4462 | 0.030 | -0.1047 | No |
| 25 | RBP1 | RBP1 Entrez, Source | retinol binding protein 1, cellular | 4518 | 0.030 | -0.1054 | No |
| 26 | GJA1 | GJA1 Entrez, Source | gap junction protein, alpha 1, 43kDa (connexin 43) | 4783 | 0.027 | -0.1223 | No |
| 27 | CACYBP | CACYBP Entrez, Source | calcyclin binding protein | 4817 | 0.026 | -0.1218 | No |
| 28 | LAPTM5 | LAPTM5 Entrez, Source | lysosomal associated multispanning membrane protein 5 | 4925 | 0.025 | -0.1270 | No |
| 29 | CDKN1C | CDKN1C Entrez, Source | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 5020 | 0.024 | -0.1315 | No |
| 30 | ADIPOQ | ADIPOQ Entrez, Source | adiponectin, C1Q and collagen domain containing | 5211 | 0.021 | -0.1434 | No |
| 31 | SERPINF1 | SERPINF1 Entrez, Source | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 5398 | 0.019 | -0.1552 | No |
| 32 | CCND2 | CCND2 Entrez, Source | cyclin D2 | 5771 | 0.015 | -0.1816 | No |
| 33 | ACADM | ACADM Entrez, Source | acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain | 5845 | 0.014 | -0.1854 | No |
| 34 | EVL | EVL Entrez, Source | Enah/Vasp-like | 5897 | 0.014 | -0.1877 | No |
| 35 | NID1 | NID1 Entrez, Source | nidogen 1 | 6040 | 0.012 | -0.1970 | No |
| 36 | NID2 | NID2 Entrez, Source | nidogen 2 (osteonidogen) | 6282 | 0.010 | -0.2141 | No |
| 37 | RPS14 | RPS14 Entrez, Source | ribosomal protein S14 | 6319 | 0.009 | -0.2157 | No |
| 38 | COL3A1 | COL3A1 Entrez, Source | collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) | 6389 | 0.009 | -0.2199 | No |
| 39 | PMP22 | PMP22 Entrez, Source | peripheral myelin protein 22 | 6574 | 0.007 | -0.2331 | No |
| 40 | MORF4L1 | MORF4L1 Entrez, Source | mortality factor 4 like 1 | 6704 | 0.005 | -0.2422 | No |
| 41 | CLK1 | CLK1 Entrez, Source | CDC-like kinase 1 | 7055 | 0.001 | -0.2685 | No |
| 42 | ANGPTL2 | ANGPTL2 Entrez, Source | angiopoietin-like 2 | 7080 | 0.001 | -0.2702 | No |
| 43 | FMO1 | FMO1 Entrez, Source | flavin containing monooxygenase 1 | 7292 | -0.001 | -0.2859 | No |
| 44 | SKP1A | SKP1A Entrez, Source | S-phase kinase-associated protein 1A (p19A) | 7360 | -0.002 | -0.2908 | No |
| 45 | APOE | APOE Entrez, Source | apolipoprotein E | 7411 | -0.003 | -0.2942 | No |
| 46 | HBA-A1 | 7541 | -0.004 | -0.3035 | No | ||
| 47 | ELN | ELN Entrez, Source | elastin (supravalvular aortic stenosis, Williams-Beuren syndrome) | 7755 | -0.007 | -0.3188 | No |
| 48 | COL5A2 | COL5A2 Entrez, Source | collagen, type V, alpha 2 | 7962 | -0.009 | -0.3334 | No |
| 49 | TYROBP | TYROBP Entrez, Source | TYRO protein tyrosine kinase binding protein | 8125 | -0.011 | -0.3444 | No |
| 50 | CTSZ | CTSZ Entrez, Source | cathepsin Z | 8280 | -0.013 | -0.3545 | No |
| 51 | ALAS2 | ALAS2 Entrez, Source | aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia) | 8816 | -0.019 | -0.3927 | No |
| 52 | LUM | LUM Entrez, Source | lumican | 8862 | -0.020 | -0.3938 | No |
| 53 | LPL | LPL Entrez, Source | lipoprotein lipase | 8894 | -0.020 | -0.3939 | No |
| 54 | IGSF4 | IGSF4 Entrez, Source | immunoglobulin superfamily, member 4 | 9136 | -0.024 | -0.4094 | No |
| 55 | BZW1 | BZW1 Entrez, Source | basic leucine zipper and W2 domains 1 | 9170 | -0.024 | -0.4091 | No |
| 56 | SS18 | SS18 Entrez, Source | synovial sarcoma translocation, chromosome 18 | 9223 | -0.025 | -0.4102 | No |
| 57 | B2M | B2M Entrez, Source | beta-2-microglobulin | 9260 | -0.025 | -0.4100 | No |
| 58 | CNN3 | CNN3 Entrez, Source | calponin 3, acidic | 9383 | -0.027 | -0.4161 | No |
| 59 | ID2 | ID2 Entrez, Source | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 9384 | -0.027 | -0.4130 | No |
| 60 | DNAJA1 | DNAJA1 Entrez, Source | DnaJ (Hsp40) homolog, subfamily A, member 1 | 9406 | -0.028 | -0.4114 | No |
| 61 | SMAD1 | SMAD1 Entrez, Source | SMAD, mothers against DPP homolog 1 (Drosophila) | 9561 | -0.030 | -0.4196 | No |
| 62 | ITM2B | ITM2B Entrez, Source | integral membrane protein 2B | 9609 | -0.031 | -0.4197 | No |
| 63 | ACADL | ACADL Entrez, Source | acyl-Coenzyme A dehydrogenase, long chain | 9656 | -0.031 | -0.4196 | No |
| 64 | ARSA | ARSA Entrez, Source | arylsulfatase A | 9681 | -0.032 | -0.4177 | No |
| 65 | CCNG1 | CCNG1 Entrez, Source | cyclin G1 | 10280 | -0.041 | -0.4582 | No |
| 66 | BAX | BAX Entrez, Source | BCL2-associated X protein | 10281 | -0.041 | -0.4535 | No |
| 67 | SEPT2 | SEPT2 Entrez, Source | septin 2 | 10339 | -0.042 | -0.4530 | No |
| 68 | NFKBIA | NFKBIA Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 10388 | -0.043 | -0.4517 | No |
| 69 | LYL1 | LYL1 Entrez, Source | lymphoblastic leukemia derived sequence 1 | 10489 | -0.045 | -0.4541 | No |
| 70 | ITGB1 | ITGB1 Entrez, Source | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 10521 | -0.046 | -0.4512 | No |
| 71 | GADD45B | GADD45B Entrez, Source | growth arrest and DNA-damage-inducible, beta | 10614 | -0.047 | -0.4528 | No |
| 72 | CDC42 | CDC42 Entrez, Source | cell division cycle 42 (GTP binding protein, 25kDa) | 10703 | -0.049 | -0.4537 | No |
| 73 | LAPTM4A | LAPTM4A Entrez, Source | lysosomal-associated protein transmembrane 4 alpha | 10730 | -0.050 | -0.4500 | No |
| 74 | RBBP7 | RBBP7 Entrez, Source | retinoblastoma binding protein 7 | 10820 | -0.052 | -0.4507 | No |
| 75 | COL18A1 | COL18A1 Entrez, Source | collagen, type XVIII, alpha 1 | 10828 | -0.052 | -0.4453 | No |
| 76 | CAPZA2 | CAPZA2 Entrez, Source | capping protein (actin filament) muscle Z-line, alpha 2 | 10967 | -0.055 | -0.4494 | No |
| 77 | GNB1 | GNB1 Entrez, Source | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 11004 | -0.056 | -0.4457 | No |
| 78 | SCG2 | SCG2 Entrez, Source | secretogranin II (chromogranin C) | 11333 | -0.063 | -0.4633 | No |
| 79 | TIMM22 | TIMM22 Entrez, Source | translocase of inner mitochondrial membrane 22 homolog (yeast) | 11445 | -0.066 | -0.4640 | No |
| 80 | NFIB | NFIB Entrez, Source | nuclear factor I/B | 11596 | -0.072 | -0.4672 | No |
| 81 | DCN | DCN Entrez, Source | decorin | 11977 | -0.086 | -0.4861 | Yes |
| 82 | NPTN | NPTN Entrez, Source | neuroplastin | 12006 | -0.087 | -0.4782 | Yes |
| 83 | CALM2 | CALM2 Entrez, Source | calmodulin 2 (phosphorylase kinase, delta) | 12036 | -0.089 | -0.4702 | Yes |
| 84 | ACTA2 | ACTA2 Entrez, Source | actin, alpha 2, smooth muscle, aorta | 12081 | -0.091 | -0.4631 | Yes |
| 85 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 12106 | -0.092 | -0.4545 | Yes |
| 86 | GSN | GSN Entrez, Source | gelsolin (amyloidosis, Finnish type) | 12230 | -0.098 | -0.4525 | Yes |
| 87 | S100A10 | S100A10 Entrez, Source | S100 calcium binding protein A10 | 12269 | -0.101 | -0.4438 | Yes |
| 88 | TUBB | TUBB Entrez, Source | tubulin, beta | 12364 | -0.108 | -0.4385 | Yes |
| 89 | EMP1 | EMP1 Entrez, Source | epithelial membrane protein 1 | 12519 | -0.119 | -0.4365 | Yes |
| 90 | GAS6 | GAS6 Entrez, Source | growth arrest-specific 6 | 12538 | -0.120 | -0.4241 | Yes |
| 91 | LMNA | LMNA Entrez, Source | lamin A/C | 12554 | -0.122 | -0.4113 | Yes |
| 92 | ANXA2 | ANXA2 Entrez, Source | annexin A2 | 12686 | -0.133 | -0.4059 | Yes |
| 93 | DSTN | DSTN Entrez, Source | destrin (actin depolymerizing factor) | 12710 | -0.136 | -0.3921 | Yes |
| 94 | GNAI2 | GNAI2 Entrez, Source | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | 12765 | -0.143 | -0.3797 | Yes |
| 95 | CSRP1 | CSRP1 Entrez, Source | cysteine and glycine-rich protein 1 | 12832 | -0.153 | -0.3672 | Yes |
| 96 | KITLG | KITLG Entrez, Source | KIT ligand | 12923 | -0.170 | -0.3545 | Yes |
| 97 | CD47 | CD47 Entrez, Source | CD47 molecule | 12956 | -0.177 | -0.3366 | Yes |
| 98 | SLC25A4 | SLC25A4 Entrez, Source | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 | 12996 | -0.187 | -0.3181 | Yes |
| 99 | ANXA3 | ANXA3 Entrez, Source | annexin A3 | 13112 | -0.236 | -0.2998 | Yes |
| 100 | DAB2 | DAB2 Entrez, Source | disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) | 13130 | -0.247 | -0.2727 | Yes |
| 101 | TMSB4X | TMSB4X Entrez, Source | thymosin, beta 4, X-linked | 13134 | -0.249 | -0.2445 | Yes |
| 102 | S100A11 | S100A11 Entrez, Source | S100 calcium binding protein A11 | 13163 | -0.267 | -0.2160 | Yes |
| 103 | SERPINB6A | 13217 | -0.312 | -0.1842 | Yes | ||
| 104 | S100A6 | S100A6 Entrez, Source | S100 calcium binding protein A6 | 13234 | -0.331 | -0.1475 | Yes |
| 105 | LCP1 | LCP1 Entrez, Source | lymphocyte cytosolic protein 1 (L-plastin) | 13280 | -0.405 | -0.1045 | Yes |
| 106 | SERPINH1 | SERPINH1 Entrez, Source | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | 13296 | -0.454 | -0.0537 | Yes |
| 107 | ANXA1 | ANXA1 Entrez, Source | annexin A1 | 13312 | -0.498 | 0.0023 | Yes |
