Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | IL2PATHWAY |
| Enrichment Score (ES) | 0.60966074 |
| Normalized Enrichment Score (NES) | 1.7762089 |
| Nominal p-value | 0.006289308 |
| FDR q-value | 0.036452603 |
| FWER p-Value | 0.946 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FOS | FOS Entrez, Source | v-fos FBJ murine osteosarcoma viral oncogene homolog | 0 | 1.012 | 0.5763 | Yes |
| 2 | IL2RG | IL2RG Entrez, Source | interleukin 2 receptor, gamma (severe combined immunodeficiency) | 503 | 0.125 | 0.6097 | Yes |
| 3 | STAT5A | STAT5A Entrez, Source | signal transducer and activator of transcription 5A | 1674 | 0.075 | 0.5645 | No |
| 4 | RAF1 | RAF1 Entrez, Source | v-raf-1 murine leukemia viral oncogene homolog 1 | 2284 | 0.062 | 0.5544 | No |
| 5 | SHC1 | SHC1 Entrez, Source | SHC (Src homology 2 domain containing) transforming protein 1 | 2417 | 0.060 | 0.5787 | No |
| 6 | IL2RB | IL2RB Entrez, Source | interleukin 2 receptor, beta | 4191 | 0.034 | 0.4649 | No |
| 7 | SYK | SYK Entrez, Source | spleen tyrosine kinase | 5948 | 0.013 | 0.3407 | No |
| 8 | CSNK2A1 | CSNK2A1 Entrez, Source | casein kinase 2, alpha 1 polypeptide | 6997 | 0.002 | 0.2631 | No |
| 9 | STAT5B | STAT5B Entrez, Source | signal transducer and activator of transcription 5B | 7024 | 0.002 | 0.2621 | No |
| 10 | GRB2 | GRB2 Entrez, Source | growth factor receptor-bound protein 2 | 7179 | 0.000 | 0.2506 | No |
| 11 | JUN | JUN Entrez, Source | jun oncogene | 8081 | -0.010 | 0.1888 | No |
| 12 | JAK3 | JAK3 Entrez, Source | Janus kinase 3 (a protein tyrosine kinase, leukocyte) | 8088 | -0.010 | 0.1943 | No |
| 13 | MAP2K1 | MAP2K1 Entrez, Source | mitogen-activated protein kinase kinase 1 | 8219 | -0.012 | 0.1914 | No |
| 14 | IL2 | IL2 Entrez, Source | interleukin 2 | 8295 | -0.013 | 0.1932 | No |
| 15 | HRAS | HRAS Entrez, Source | v-Ha-ras Harvey rat sarcoma viral oncogene homolog | 9267 | -0.025 | 0.1348 | No |
| 16 | IL2RA | IL2RA Entrez, Source | interleukin 2 receptor, alpha | 9496 | -0.029 | 0.1341 | No |
| 17 | JAK1 | JAK1 Entrez, Source | Janus kinase 1 (a protein tyrosine kinase) | 10118 | -0.039 | 0.1096 | No |
| 18 | ELK1 | ELK1 Entrez, Source | ELK1, member of ETS oncogene family | 12262 | -0.100 | 0.0060 | No |
| 19 | MAPK3 | MAPK3 Entrez, Source | mitogen-activated protein kinase 3 | 12674 | -0.132 | 0.0501 | No |
