Details for gene set INSULIN

Table: GSEA Results Summary

Dataset	double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos
Phenotype	class.cls#double_gel_48h_versus_single_gel_48h_repos
Upregulated in class	double_gel_48h
GeneSet	INSULIN_SIGNALING
Enrichment Score (ES)	0.43460816
Normalized Enrichment Score (NES)	1.7007843
Nominal p-value	0.0
FDR q-value	0.058962576
FWER p-Value	1.0

Table: GSEA details [plain text format]
	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	FOS	FOS Entrez, Source	v-fos FBJ murine osteosarcoma viral oncogene homolog	0	1.012	0.1351	Yes
2	G6PC	G6PC Entrez, Source	glucose-6-phosphatase, catalytic subunit	26	0.337	0.1783	Yes
3	CEBPA	CEBPA Entrez, Source	CCAAT/enhancer binding protein (C/EBP), alpha	46	0.289	0.2154	Yes
4	FBP1	FBP1 Entrez, Source	fructose-1,6-bisphosphatase 1	67	0.255	0.2480	Yes
5	PKLR	PKLR Entrez, Source	pyruvate kinase, liver and RBC	74	0.247	0.2806	Yes
6	ACACA	ACACA Entrez, Source	acetyl-Coenzyme A carboxylase alpha	157	0.190	0.2998	Yes
7	GCK	GCK Entrez, Source	glucokinase (hexokinase 4, maturity onset diabetes of the young 2)	218	0.170	0.3179	Yes
8	ACOX1	ACOX1 Entrez, Source	acyl-Coenzyme A oxidase 1, palmitoyl	227	0.165	0.3393	Yes
9	IRS1	IRS1 Entrez, Source	insulin receptor substrate 1	233	0.163	0.3607	Yes
10	IGFBP1	IGFBP1 Entrez, Source	insulin-like growth factor binding protein 1	459	0.129	0.3610	Yes
11	UCP1	UCP1 Entrez, Source	uncoupling protein 1 (mitochondrial, proton carrier)	627	0.117	0.3640	Yes
12	CEBPB	CEBPB Entrez, Source	CCAAT/enhancer binding protein (C/EBP), beta	732	0.110	0.3709	Yes
13	INSR	INSR Entrez, Source	insulin receptor	772	0.108	0.3823	Yes
14	PPARG	PPARG Entrez, Source	peroxisome proliferative activated receptor, gamma	801	0.107	0.3945	Yes
15	BRAF	BRAF Entrez, Source	v-raf murine sarcoma viral oncogene homolog B1	842	0.105	0.4055	Yes
16	AKT3	AKT3 Entrez, Source	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	871	0.104	0.4173	Yes
17	SLC2A4	SLC2A4 Entrez, Source	solute carrier family 2 (facilitated glucose transporter), member 4	900	0.102	0.4289	Yes
18	LDLR	LDLR Entrez, Source	low density lipoprotein receptor (familial hypercholesterolemia)	998	0.098	0.4346	Yes
19	PRL	PRL Entrez, Source	prolactin	1687	0.075	0.3927	No
20	GCG	GCG Entrez, Source	glucagon	1704	0.074	0.4014	No
21	VEGF	VEGF Entrez, Source	vascular endothelial growth factor	1883	0.070	0.3974	No
22	RAF1	RAF1 Entrez, Source	v-raf-1 murine leukemia viral oncogene homolog 1	2284	0.062	0.3756	No
23	SHC1	SHC1 Entrez, Source	SHC (Src homology 2 domain containing) transforming protein 1	2417	0.060	0.3736	No
24	PIK3R1	PIK3R1 Entrez, Source	phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha)	2668	0.056	0.3622	No
25	PIK3R3	PIK3R3 Entrez, Source	phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma)	3943	0.037	0.2712	No
26	FRAP1	FRAP1 Entrez, Source	FK506 binding protein 12-rapamycin associated protein 1	3947	0.037	0.2759	No
27	SREBF1	SREBF1 Entrez, Source	sterol regulatory element binding transcription factor 1	4109	0.035	0.2685	No
28	LNPEP	LNPEP Entrez, Source	leucyl/cystinyl aminopeptidase	4126	0.035	0.2719	No
29	AKT2	AKT2 Entrez, Source	v-akt murine thymoma viral oncogene homolog 2	4202	0.034	0.2707	No
30	EIF2B1	EIF2B1 Entrez, Source	eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa	4517	0.030	0.2511	No
31	PRKCB1	PRKCB1 Entrez, Source	protein kinase C, beta 1	4579	0.029	0.2503	No
32	RPS6KB1	RPS6KB1 Entrez, Source	ribosomal protein S6 kinase, 70kDa, polypeptide 1	4614	0.028	0.2516	No
33	ADRB3	ADRB3 Entrez, Source	adrenergic, beta-3-, receptor	5128	0.022	0.2159	No
34	TG	TG Entrez, Source	thyroglobulin	5245	0.021	0.2099	No
35	ORM1	ORM1 Entrez, Source	orosomucoid 1	5486	0.019	0.1943	No
36	PDPK1	PDPK1 Entrez, Source	3-phosphoinositide dependent protein kinase-1	5563	0.018	0.1909	No
37	GSK3A	GSK3A Entrez, Source	glycogen synthase kinase 3 alpha	5648	0.017	0.1868	No
38	EIF4E	EIF4E Entrez, Source	eukaryotic translation initiation factor 4E	5790	0.015	0.1782	No
39	PRKCZ	PRKCZ Entrez, Source	protein kinase C, zeta	6220	0.011	0.1473	No
40	ACACB	ACACB Entrez, Source	acetyl-Coenzyme A carboxylase beta	6337	0.009	0.1398	No
41	MAPK1	MAPK1 Entrez, Source	mitogen-activated protein kinase 1	6633	0.006	0.1184	No
42	BRD4	BRD4 Entrez, Source	bromodomain containing 4	6958	0.002	0.0943	No
43	GRB2	GRB2 Entrez, Source	growth factor receptor-bound protein 2	7179	0.000	0.0777	No
44	PPIA	PPIA Entrez, Source	peptidylprolyl isomerase A (cyclophilin A)	7249	-0.001	0.0726	No
45	PTPN11	PTPN11 Entrez, Source	protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1)	7325	-0.002	0.0672	No
46	RPL13A	RPL13A Entrez, Source	ribosomal protein L13a	7679	-0.006	0.0413	No
47	PIK3CB	PIK3CB Entrez, Source	phosphoinositide-3-kinase, catalytic, beta polypeptide	8066	-0.010	0.0136	No
48	JUN	JUN Entrez, Source	jun oncogene	8081	-0.010	0.0139	No
49	MAP2K1	MAP2K1 Entrez, Source	mitogen-activated protein kinase kinase 1	8219	-0.012	0.0052	No
50	EIF4EBP1	EIF4EBP1 Entrez, Source	eukaryotic translation initiation factor 4E binding protein 1	8352	-0.014	-0.0029	No
51	RPS6KA1	RPS6KA1 Entrez, Source	ribosomal protein S6 kinase, 90kDa, polypeptide 1	9175	-0.024	-0.0617	No
52	HRAS	HRAS Entrez, Source	v-Ha-ras Harvey rat sarcoma viral oncogene homolog	9267	-0.025	-0.0651	No
53	SOS2	SOS2 Entrez, Source	son of sevenless homolog 2 (Drosophila)	9696	-0.032	-0.0931	No
54	UCP2	UCP2 Entrez, Source	uncoupling protein 2 (mitochondrial, proton carrier)	9763	-0.033	-0.0937	No
55	SLC27A4	SLC27A4 Entrez, Source	solute carrier family 27 (fatty acid transporter), member 4	9907	-0.035	-0.0998	No
56	CRK	CRK Entrez, Source	v-crk sarcoma virus CT10 oncogene homolog (avian)	10537	-0.046	-0.1411	No
57	HK2	HK2 Entrez, Source	hexokinase 2	10644	-0.048	-0.1427	No
58	PPP1CA	PPP1CA Entrez, Source	protein phosphatase 1, catalytic subunit, alpha isoform	10652	-0.048	-0.1368	No
59	BCL2L1	BCL2L1 Entrez, Source	BCL2-like 1	10657	-0.048	-0.1307	No
60	CSN2	CSN2 Entrez, Source	casein beta	10708	-0.050	-0.1278	No
61	PIK3R2	PIK3R2 Entrez, Source	phosphoinositide-3-kinase, regulatory subunit 2 (p85 beta)	10802	-0.052	-0.1279	No
62	MAP2K2	MAP2K2 Entrez, Source	mitogen-activated protein kinase kinase 2	10890	-0.053	-0.1274	No
63	ACTB	ACTB Entrez, Source	actin, beta	11264	-0.061	-0.1473	No
64	LEP	LEP Entrez, Source	leptin (obesity homolog, mouse)	11480	-0.068	-0.1544	No
65	GSK3B	GSK3B Entrez, Source	glycogen synthase kinase 3 beta	11670	-0.074	-0.1587	No
66	AKT1	AKT1 Entrez, Source	v-akt murine thymoma viral oncogene homolog 1	11925	-0.084	-0.1666	No
67	PRKCI	PRKCI Entrez, Source	protein kinase C, iota	12255	-0.100	-0.1781	No
68	DOK1	DOK1 Entrez, Source	docking protein 1, 62kDa (downstream of tyrosine kinase 1)	12620	-0.127	-0.1885	No
69	PTPRF	PTPRF Entrez, Source	protein tyrosine phosphatase, receptor type, F	12684	-0.133	-0.1755	No
70	PTPN1	PTPN1 Entrez, Source	protein tyrosine phosphatase, non-receptor type 1	12685	-0.133	-0.1577	No
71	CAP1	CAP1 Entrez, Source	CAP, adenylate cyclase-associated protein 1 (yeast)	12748	-0.141	-0.1436	No
72	PIK3CA	PIK3CA Entrez, Source	phosphoinositide-3-kinase, catalytic, alpha polypeptide	12788	-0.146	-0.1271	No
73	NPY	NPY Entrez, Source	neuropeptide Y	13095	-0.230	-0.1194	No
74	RRAS2	RRAS2 Entrez, Source	related RAS viral (r-ras) oncogene homolog 2	13125	-0.244	-0.0890	No
75	SLC2A1	SLC2A1 Entrez, Source	solute carrier family 2 (facilitated glucose transporter), member 1	13210	-0.303	-0.0548	No
76	SERPINE1	SERPINE1 Entrez, Source	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	13308	-0.484	0.0026	No