Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | INTEGRINPATHWAY |
| Enrichment Score (ES) | -0.7240991 |
| Normalized Enrichment Score (NES) | -2.108486 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0036880414 |
| FWER p-Value | 0.038 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FYN | FYN Entrez, Source | FYN oncogene related to SRC, FGR, YES | 1682 | 0.075 | -0.1039 | No |
| 2 | CRKL | CRKL Entrez, Source | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | 2223 | 0.064 | -0.1254 | No |
| 3 | RAF1 | RAF1 Entrez, Source | v-raf-1 murine leukemia viral oncogene homolog 1 | 2284 | 0.062 | -0.1112 | No |
| 4 | SHC1 | SHC1 Entrez, Source | SHC (Src homology 2 domain containing) transforming protein 1 | 2417 | 0.060 | -0.1031 | No |
| 5 | SRC | SRC Entrez, Source | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 3918 | 0.038 | -0.2045 | No |
| 6 | MAPK1 | MAPK1 Entrez, Source | mitogen-activated protein kinase 1 | 6633 | 0.006 | -0.4065 | No |
| 7 | RAP1A | RAP1A Entrez, Source | RAP1A, member of RAS oncogene family | 7041 | 0.002 | -0.4366 | No |
| 8 | GRB2 | GRB2 Entrez, Source | growth factor receptor-bound protein 2 | 7179 | 0.000 | -0.4469 | No |
| 9 | CSK | CSK Entrez, Source | c-src tyrosine kinase | 7615 | -0.005 | -0.4781 | No |
| 10 | ITGA1 | ITGA1 Entrez, Source | integrin, alpha 1 | 7816 | -0.007 | -0.4909 | No |
| 11 | JUN | JUN Entrez, Source | jun oncogene | 8081 | -0.010 | -0.5076 | No |
| 12 | MAP2K1 | MAP2K1 Entrez, Source | mitogen-activated protein kinase kinase 1 | 8219 | -0.012 | -0.5143 | No |
| 13 | HRAS | HRAS Entrez, Source | v-Ha-ras Harvey rat sarcoma viral oncogene homolog | 9267 | -0.025 | -0.5853 | No |
| 14 | ROCK1 | ROCK1 Entrez, Source | Rho-associated, coiled-coil containing protein kinase 1 | 9904 | -0.035 | -0.6226 | No |
| 15 | ITGB1 | ITGB1 Entrez, Source | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 10521 | -0.046 | -0.6552 | No |
| 16 | TLN1 | TLN1 Entrez, Source | talin 1 | 10840 | -0.052 | -0.6634 | No |
| 17 | MAP2K2 | MAP2K2 Entrez, Source | mitogen-activated protein kinase kinase 2 | 10890 | -0.053 | -0.6510 | No |
| 18 | PTK2 | PTK2 Entrez, Source | PTK2 protein tyrosine kinase 2 | 10930 | -0.054 | -0.6377 | No |
| 19 | CAPNS1 | CAPNS1 Entrez, Source | calpain, small subunit 1 | 12082 | -0.091 | -0.6968 | Yes |
| 20 | CAPN1 | CAPN1 Entrez, Source | calpain 1, (mu/I) large subunit | 12425 | -0.112 | -0.6889 | Yes |
| 21 | BCAR1 | BCAR1 Entrez, Source | breast cancer anti-estrogen resistance 1 | 12497 | -0.117 | -0.6591 | Yes |
| 22 | MAPK3 | MAPK3 Entrez, Source | mitogen-activated protein kinase 3 | 12674 | -0.132 | -0.6328 | Yes |
| 23 | PXN | PXN Entrez, Source | paxillin | 12950 | -0.176 | -0.6008 | Yes |
| 24 | ACTN3 | ACTN3 Entrez, Source | actinin, alpha 3 | 13042 | -0.204 | -0.5464 | Yes |
| 25 | ZYX | ZYX Entrez, Source | zyxin | 13115 | -0.238 | -0.4804 | Yes |
| 26 | ACTN1 | ACTN1 Entrez, Source | actinin, alpha 1 | 13303 | -0.473 | -0.3528 | Yes |
| 27 | ACTA1 | ACTA1 Entrez, Source | actin, alpha 1, skeletal muscle | 13342 | -1.187 | -0.0000 | Yes |
