Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | IRITANI_ADPROX_DN |
| Enrichment Score (ES) | -0.6204672 |
| Normalized Enrichment Score (NES) | -1.9506541 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.01480414 |
| FWER p-Value | 0.409 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | IGF2BP3 | IGF2BP3 Entrez, Source | insulin-like growth factor 2 mRNA binding protein 3 | 531 | 0.123 | -0.0123 | No |
| 2 | CAP2 | CAP2 Entrez, Source | CAP, adenylate cyclase-associated protein, 2 (yeast) | 940 | 0.100 | -0.0205 | No |
| 3 | SRPX | SRPX Entrez, Source | sushi-repeat-containing protein, X-linked | 1692 | 0.074 | -0.0602 | No |
| 4 | NRCAM | NRCAM Entrez, Source | neuronal cell adhesion molecule | 1953 | 0.069 | -0.0642 | No |
| 5 | CDH2 | CDH2 Entrez, Source | cadherin 2, type 1, N-cadherin (neuronal) | 2163 | 0.065 | -0.0654 | No |
| 6 | BMP6 | BMP6 Entrez, Source | bone morphogenetic protein 6 | 2251 | 0.063 | -0.0578 | No |
| 7 | LPXN | LPXN Entrez, Source | leupaxin | 2384 | 0.061 | -0.0541 | No |
| 8 | PLAU | PLAU Entrez, Source | plasminogen activator, urokinase | 3505 | 0.043 | -0.1287 | No |
| 9 | PRG1 | PRG1 Entrez, Source | proteoglycan 1, secretory granule | 3518 | 0.043 | -0.1200 | No |
| 10 | PLA2G4A | PLA2G4A Entrez, Source | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 4307 | 0.033 | -0.1719 | No |
| 11 | MAPKAPK3 | MAPKAPK3 Entrez, Source | mitogen-activated protein kinase-activated protein kinase 3 | 4926 | 0.025 | -0.2128 | No |
| 12 | ARHGDIB | ARHGDIB Entrez, Source | Rho GDP dissociation inhibitor (GDI) beta | 6080 | 0.012 | -0.2968 | No |
| 13 | IL6 | IL6 Entrez, Source | interleukin 6 (interferon, beta 2) | 6864 | 0.004 | -0.3548 | No |
| 14 | ICAM2 | ICAM2 Entrez, Source | intercellular adhesion molecule 2 | 7616 | -0.005 | -0.4102 | No |
| 15 | EMP3 | EMP3 Entrez, Source | epithelial membrane protein 3 | 7711 | -0.006 | -0.4159 | No |
| 16 | FAP | FAP Entrez, Source | fibroblast activation protein, alpha | 8035 | -0.010 | -0.4380 | No |
| 17 | LTBP2 | LTBP2 Entrez, Source | latent transforming growth factor beta binding protein 2 | 8356 | -0.014 | -0.4589 | No |
| 18 | TFEC | TFEC Entrez, Source | transcription factor EC | 8378 | -0.014 | -0.4574 | No |
| 19 | RGS4 | RGS4 Entrez, Source | regulator of G-protein signalling 4 | 8726 | -0.018 | -0.4794 | No |
| 20 | SELP | SELP Entrez, Source | selectin P (granule membrane protein 140kDa, antigen CD62) | 9119 | -0.023 | -0.5036 | No |
| 21 | NRP1 | NRP1 Entrez, Source | neuropilin 1 | 9147 | -0.024 | -0.5003 | No |
| 22 | ANXA6 | ANXA6 Entrez, Source | annexin A6 | 9885 | -0.035 | -0.5480 | No |
| 23 | PDLIM4 | PDLIM4 Entrez, Source | PDZ and LIM domain 4 | 9887 | -0.035 | -0.5403 | No |
| 24 | LYL1 | LYL1 Entrez, Source | lymphoblastic leukemia derived sequence 1 | 10489 | -0.045 | -0.5753 | No |
| 25 | MLLT11 | MLLT11 Entrez, Source | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 11034 | -0.057 | -0.6035 | Yes |
| 26 | TCN2 | TCN2 Entrez, Source | transcobalamin II; macrocytic anemia | 11172 | -0.060 | -0.6004 | Yes |
| 27 | CSPG2 | CSPG2 Entrez, Source | chondroitin sulfate proteoglycan 2 (versican) | 11206 | -0.060 | -0.5893 | Yes |
| 28 | PFKM | PFKM Entrez, Source | phosphofructokinase, muscle | 11295 | -0.062 | -0.5820 | Yes |
| 29 | AXL | AXL Entrez, Source | AXL receptor tyrosine kinase | 11348 | -0.064 | -0.5716 | Yes |
| 30 | MMP14 | MMP14 Entrez, Source | matrix metallopeptidase 14 (membrane-inserted) | 11798 | -0.079 | -0.5876 | Yes |
| 31 | SLC38A6 | SLC38A6 Entrez, Source | solute carrier family 38, member 6 | 12236 | -0.099 | -0.5983 | Yes |
| 32 | CD59 | CD59 Entrez, Source | CD59 molecule, complement regulatory protein | 12353 | -0.107 | -0.5829 | Yes |
| 33 | ARL6IP5 | ARL6IP5 Entrez, Source | ADP-ribosylation-like factor 6 interacting protein 5 | 12496 | -0.117 | -0.5672 | Yes |
| 34 | CD44 | CD44 Entrez, Source | CD44 molecule (Indian blood group) | 12977 | -0.184 | -0.5620 | Yes |
| 35 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 12980 | -0.185 | -0.5207 | Yes |
| 36 | LDHB | LDHB Entrez, Source | lactate dehydrogenase B | 13053 | -0.209 | -0.4792 | Yes |
| 37 | PRNP | PRNP Entrez, Source | prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia) | 13090 | -0.227 | -0.4310 | Yes |
| 38 | PROCR | PROCR Entrez, Source | protein C receptor, endothelial (EPCR) | 13292 | -0.436 | -0.3483 | Yes |
| 39 | GBP2 | GBP2 Entrez, Source | guanylate binding protein 2, interferon-inducible | 13295 | -0.454 | -0.2464 | Yes |
| 40 | SERPINE1 | SERPINE1 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 13308 | -0.484 | -0.1384 | Yes |
| 41 | CCL2 | CCL2 Entrez, Source | chemokine (C-C motif) ligand 2 | 13326 | -0.627 | 0.0012 | Yes |
