Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | IRITANI_ADPROX_LYMPH |
| Enrichment Score (ES) | -0.5061566 |
| Normalized Enrichment Score (NES) | -1.7939026 |
| Nominal p-value | 0.0015600624 |
| FDR q-value | 0.042656217 |
| FWER p-Value | 0.98 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | DHCR24 | DHCR24 Entrez, Source | 24-dehydrocholesterol reductase | 167 | 0.185 | 0.0145 | No |
| 2 | CXCL12 | CXCL12 Entrez, Source | chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) | 295 | 0.150 | 0.0269 | No |
| 3 | RGS16 | RGS16 Entrez, Source | regulator of G-protein signalling 16 | 335 | 0.144 | 0.0450 | No |
| 4 | GCH1 | GCH1 Entrez, Source | GTP cyclohydrolase 1 (dopa-responsive dystonia) | 441 | 0.131 | 0.0563 | No |
| 5 | CEACAM1 | CEACAM1 Entrez, Source | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 932 | 0.101 | 0.0341 | No |
| 6 | RAMP3 | RAMP3 Entrez, Source | receptor (calcitonin) activity modifying protein 3 | 1115 | 0.093 | 0.0340 | No |
| 7 | ACSL3 | ACSL3 Entrez, Source | acyl-CoA synthetase long-chain family member 3 | 1240 | 0.088 | 0.0375 | No |
| 8 | SLC26A4 | SLC26A4 Entrez, Source | solute carrier family 26, member 4 | 1409 | 0.082 | 0.0369 | No |
| 9 | PDPN | PDPN Entrez, Source | podoplanin | 1510 | 0.079 | 0.0410 | No |
| 10 | ALDH1A1 | ALDH1A1 Entrez, Source | aldehyde dehydrogenase 1 family, member A1 | 1653 | 0.076 | 0.0414 | No |
| 11 | CYP1A1 | CYP1A1 Entrez, Source | cytochrome P450, family 1, subfamily A, polypeptide 1 | 1719 | 0.074 | 0.0472 | No |
| 12 | RAPGEF5 | RAPGEF5 Entrez, Source | Rap guanine nucleotide exchange factor (GEF) 5 | 1793 | 0.072 | 0.0523 | No |
| 13 | CALCRL | CALCRL Entrez, Source | calcitonin receptor-like | 1986 | 0.069 | 0.0479 | No |
| 14 | APOD | APOD Entrez, Source | apolipoprotein D | 2550 | 0.058 | 0.0139 | No |
| 15 | MGP | MGP Entrez, Source | matrix Gla protein | 2580 | 0.057 | 0.0201 | No |
| 16 | PCSK6 | PCSK6 Entrez, Source | proprotein convertase subtilisin/kexin type 6 | 2892 | 0.052 | 0.0042 | No |
| 17 | CSNK1G1 | CSNK1G1 Entrez, Source | casein kinase 1, gamma 1 | 2899 | 0.052 | 0.0114 | No |
| 18 | SPAG5 | SPAG5 Entrez, Source | sperm associated antigen 5 | 3211 | 0.047 | -0.0052 | No |
| 19 | IGFBP2 | IGFBP2 Entrez, Source | insulin-like growth factor binding protein 2, 36kDa | 3303 | 0.046 | -0.0054 | No |
| 20 | CH25H | CH25H Entrez, Source | cholesterol 25-hydroxylase | 3370 | 0.045 | -0.0037 | No |
| 21 | CREM | CREM Entrez, Source | cAMP responsive element modulator | 3406 | 0.044 | 0.0001 | No |
| 22 | SEPP1 | SEPP1 Entrez, Source | selenoprotein P, plasma, 1 | 3423 | 0.044 | 0.0054 | No |
| 23 | DCAMKL1 | DCAMKL1 Entrez, Source | doublecortin and CaM kinase-like 1 | 3621 | 0.041 | -0.0034 | No |
| 24 | LBR | LBR Entrez, Source | lamin B receptor | 3791 | 0.039 | -0.0104 | No |
| 25 | SMC4 | SMC4 Entrez, Source | structural maintenance of chromosomes 4 | 4217 | 0.034 | -0.0375 | No |
| 26 | CDKN3 | CDKN3 Entrez, Source | cyclin-dependent kinase inhibitor 3 (CDK2-associated dual specificity phosphatase) | 4303 | 0.033 | -0.0391 | No |
| 27 | RBP1 | RBP1 Entrez, Source | retinol binding protein 1, cellular | 4518 | 0.030 | -0.0509 | No |
| 28 | LAMP3 | LAMP3 Entrez, Source | lysosomal-associated membrane protein 3 | 4591 | 0.029 | -0.0521 | No |
| 29 | CD200 | CD200 Entrez, Source | CD200 molecule | 4766 | 0.027 | -0.0613 | No |
| 30 | GRAP | GRAP Entrez, Source | GRB2-related adaptor protein | 4773 | 0.027 | -0.0578 | No |
| 31 | CDKN1C | CDKN1C Entrez, Source | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 5020 | 0.024 | -0.0729 | No |
| 32 | PYGL | PYGL Entrez, Source | phosphorylase, glycogen; liver (Hers disease, glycogen storage disease type VI) | 5160 | 0.022 | -0.0802 | No |
| 33 | MAOA | MAOA Entrez, Source | monoamine oxidase A | 5177 | 0.022 | -0.0782 | No |
| 34 | FLT4 | FLT4 Entrez, Source | fms-related tyrosine kinase 4 | 5436 | 0.019 | -0.0949 | No |
| 35 | ANGPT2 | ANGPT2 Entrez, Source | angiopoietin 2 | 5512 | 0.018 | -0.0979 | No |
| 36 | PELO | PELO Entrez, Source | pelota homolog (Drosophila) | 5700 | 0.016 | -0.1096 | No |
| 37 | PRKCZ | PRKCZ Entrez, Source | protein kinase C, zeta | 6220 | 0.011 | -0.1472 | No |
| 38 | RAMP2 | RAMP2 Entrez, Source | receptor (calcitonin) activity modifying protein 2 | 6398 | 0.009 | -0.1593 | No |
| 39 | SOCS2 | SOCS2 Entrez, Source | suppressor of cytokine signaling 2 | 6400 | 0.009 | -0.1581 | No |
| 40 | ADD3 | ADD3 Entrez, Source | adducin 3 (gamma) | 6472 | 0.008 | -0.1623 | No |
| 41 | EMP2 | EMP2 Entrez, Source | epithelial membrane protein 2 | 6612 | 0.006 | -0.1719 | No |
| 42 | PDE8A | PDE8A Entrez, Source | phosphodiesterase 8A | 6686 | 0.006 | -0.1765 | No |
| 43 | DYRK3 | DYRK3 Entrez, Source | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 6818 | 0.004 | -0.1858 | No |
| 44 | GMFG | GMFG Entrez, Source | glia maturation factor, gamma | 7245 | -0.001 | -0.2178 | No |
| 45 | PDLIM3 | PDLIM3 Entrez, Source | PDZ and LIM domain 3 | 7252 | -0.001 | -0.2182 | No |
| 46 | TFF3 | TFF3 Entrez, Source | trefoil factor 3 (intestinal) | 7322 | -0.002 | -0.2231 | No |
| 47 | PLK1 | PLK1 Entrez, Source | polo-like kinase 1 (Drosophila) | 7563 | -0.004 | -0.2406 | No |
| 48 | ITGA9 | ITGA9 Entrez, Source | integrin, alpha 9 | 7618 | -0.005 | -0.2439 | No |
| 49 | DUSP5 | DUSP5 Entrez, Source | dual specificity phosphatase 5 | 8419 | -0.014 | -0.3021 | No |
| 50 | LMO2 | LMO2 Entrez, Source | LIM domain only 2 (rhombotin-like 1) | 9073 | -0.023 | -0.3480 | No |
| 51 | FOXM1 | FOXM1 Entrez, Source | forkhead box M1 | 9257 | -0.025 | -0.3581 | No |
| 52 | TOP2A | TOP2A Entrez, Source | topoisomerase (DNA) II alpha 170kDa | 10131 | -0.039 | -0.4182 | No |
| 53 | PTTG1 | PTTG1 Entrez, Source | pituitary tumor-transforming 1 | 10625 | -0.047 | -0.4484 | No |
| 54 | FABP4 | FABP4 Entrez, Source | fatty acid binding protein 4, adipocyte | 10699 | -0.049 | -0.4467 | No |
| 55 | PPAP2A | PPAP2A Entrez, Source | phosphatidic acid phosphatase type 2A | 11084 | -0.058 | -0.4672 | No |
| 56 | BUB1B | BUB1B Entrez, Source | BUB1 budding uninhibited by benzimidazoles 1 homolog beta (yeast) | 11337 | -0.063 | -0.4769 | No |
| 57 | IL7 | IL7 Entrez, Source | interleukin 7 | 11588 | -0.071 | -0.4853 | No |
| 58 | PPP1R2 | PPP1R2 Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 2 | 11738 | -0.077 | -0.4853 | No |
| 59 | RELN | RELN Entrez, Source | reelin | 12016 | -0.088 | -0.4933 | Yes |
| 60 | LYN | LYN Entrez, Source | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 12083 | -0.091 | -0.4849 | Yes |
| 61 | CRMP1 | CRMP1 Entrez, Source | collapsin response mediator protein 1 | 12101 | -0.091 | -0.4728 | Yes |
| 62 | DSP | DSP Entrez, Source | desmoplakin | 12225 | -0.098 | -0.4677 | Yes |
| 63 | CCNB2 | CCNB2 Entrez, Source | cyclin B2 | 12396 | -0.111 | -0.4643 | Yes |
| 64 | ARRB2 | ARRB2 Entrez, Source | arrestin, beta 2 | 12544 | -0.121 | -0.4577 | Yes |
| 65 | KALRN | KALRN Entrez, Source | kalirin, RhoGEF kinase | 12586 | -0.124 | -0.4425 | Yes |
| 66 | ISG20 | ISG20 Entrez, Source | interferon stimulated exonuclease gene 20kDa | 12691 | -0.134 | -0.4308 | Yes |
| 67 | CSRP2 | CSRP2 Entrez, Source | cysteine and glycine-rich protein 2 | 12792 | -0.147 | -0.4168 | Yes |
| 68 | KIF2C | KIF2C Entrez, Source | kinesin family member 2C | 12895 | -0.164 | -0.4005 | Yes |
| 69 | PDLIM1 | PDLIM1 Entrez, Source | PDZ and LIM domain 1 (elfin) | 12939 | -0.173 | -0.3784 | Yes |
| 70 | MAF | MAF Entrez, Source | v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) | 13083 | -0.223 | -0.3564 | Yes |
| 71 | LMNB1 | LMNB1 Entrez, Source | lamin B1 | 13104 | -0.234 | -0.3237 | Yes |
| 72 | CCNB1 | CCNB1 Entrez, Source | cyclin B1 | 13126 | -0.245 | -0.2894 | Yes |
| 73 | TIMP3 | TIMP3 Entrez, Source | TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory) | 13175 | -0.275 | -0.2526 | Yes |
| 74 | RAB31 | RAB31 Entrez, Source | RAB31, member RAS oncogene family | 13200 | -0.292 | -0.2117 | Yes |
| 75 | AURKB | AURKB Entrez, Source | aurora kinase B | 13237 | -0.335 | -0.1653 | Yes |
| 76 | NDRG1 | NDRG1 Entrez, Source | N-myc downstream regulated gene 1 | 13242 | -0.345 | -0.1151 | Yes |
| 77 | CCNA2 | CCNA2 Entrez, Source | cyclin A2 | 13257 | -0.367 | -0.0624 | Yes |
| 78 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13301 | -0.469 | 0.0031 | Yes |
