Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | ISOMERASE_ACTIVITY |
| Enrichment Score (ES) | 0.6029569 |
| Normalized Enrichment Score (NES) | 1.7766409 |
| Nominal p-value | 0.013888889 |
| FDR q-value | 0.03682208 |
| FWER p-Value | 0.945 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | IDI1 | IDI1 Entrez, Source | isopentenyl-diphosphate delta isomerase 1 | 13 | 0.382 | 0.2251 | Yes |
| 2 | LSS | LSS Entrez, Source | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) | 20 | 0.353 | 0.4334 | Yes |
| 3 | EBP | EBP Entrez, Source | emopamil binding protein (sterol isomerase) | 45 | 0.290 | 0.6030 | Yes |
| 4 | GNE | GNE Entrez, Source | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase | 1441 | 0.081 | 0.5463 | No |
| 5 | PTGIS | PTGIS Entrez, Source | prostaglandin I2 (prostacyclin) synthase | 2515 | 0.058 | 0.5002 | No |
| 6 | HSD3B1 | HSD3B1 Entrez, Source | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 | 2646 | 0.056 | 0.5236 | No |
| 7 | DDT | DDT Entrez, Source | D-dopachrome tautomerase | 2762 | 0.054 | 0.5469 | No |
| 8 | TOP1 | TOP1 Entrez, Source | topoisomerase (DNA) I | 3919 | 0.038 | 0.4824 | No |
| 9 | PDIA5 | PDIA5 Entrez, Source | protein disulfide isomerase family A, member 5 | 4124 | 0.035 | 0.4876 | No |
| 10 | P4HB | P4HB Entrez, Source | procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide | 4586 | 0.029 | 0.4701 | No |
| 11 | PDIA6 | PDIA6 Entrez, Source | protein disulfide isomerase family A, member 6 | 4624 | 0.028 | 0.4840 | No |
| 12 | PDIA3 | PDIA3 Entrez, Source | protein disulfide isomerase family A, member 3 | 5084 | 0.023 | 0.4631 | No |
| 13 | PPIE | PPIE Entrez, Source | peptidylprolyl isomerase E (cyclophilin E) | 5766 | 0.015 | 0.4210 | No |
| 14 | PTGDS | PTGDS Entrez, Source | prostaglandin D2 synthase 21kDa (brain) | 6985 | 0.002 | 0.3307 | No |
| 15 | BPGM | BPGM Entrez, Source | 2,3-bisphosphoglycerate mutase | 7240 | -0.001 | 0.3121 | No |
| 16 | PGM1 | PGM1 Entrez, Source | phosphoglucomutase 1 | 7335 | -0.002 | 0.3061 | No |
| 17 | PGAM2 | PGAM2 Entrez, Source | phosphoglycerate mutase 2 (muscle) | 9063 | -0.023 | 0.1899 | No |
| 18 | TXNDC4 | TXNDC4 Entrez, Source | thioredoxin domain containing 4 (endoplasmic reticulum) | 9203 | -0.024 | 0.1939 | No |
| 19 | PMM1 | PMM1 Entrez, Source | phosphomannomutase 1 | 9922 | -0.035 | 0.1608 | No |
| 20 | TOP2A | TOP2A Entrez, Source | topoisomerase (DNA) II alpha 170kDa | 10131 | -0.039 | 0.1681 | No |
| 21 | TPI1 | TPI1 Entrez, Source | triosephosphate isomerase 1 | 10267 | -0.041 | 0.1821 | No |
| 22 | ERP29 | ERP29 Entrez, Source | endoplasmic reticulum protein 29 | 11877 | -0.082 | 0.1100 | No |
