Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | KERATINOCYTEPATHWAY |
| Enrichment Score (ES) | 0.46071786 |
| Normalized Enrichment Score (NES) | 1.519821 |
| Nominal p-value | 0.027459955 |
| FDR q-value | 0.13098742 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FOS | FOS Entrez, Source | v-fos FBJ murine osteosarcoma viral oncogene homolog | 0 | 1.012 | 0.3383 | Yes |
| 2 | CEBPA | CEBPA Entrez, Source | CCAAT/enhancer binding protein (C/EBP), alpha | 46 | 0.289 | 0.4315 | Yes |
| 3 | EGF | EGF Entrez, Source | epidermal growth factor (beta-urogastrone) | 316 | 0.148 | 0.4607 | Yes |
| 4 | PRKCQ | PRKCQ Entrez, Source | protein kinase C, theta | 928 | 0.101 | 0.4486 | No |
| 5 | PRKCE | PRKCE Entrez, Source | protein kinase C, epsilon | 2008 | 0.068 | 0.3902 | No |
| 6 | RAF1 | RAF1 Entrez, Source | v-raf-1 murine leukemia viral oncogene homolog 1 | 2284 | 0.062 | 0.3904 | No |
| 7 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 2688 | 0.055 | 0.3787 | No |
| 8 | TNFRSF1A | TNFRSF1A Entrez, Source | tumor necrosis factor receptor superfamily, member 1A | 2994 | 0.050 | 0.3725 | No |
| 9 | MAPK13 | MAPK13 Entrez, Source | mitogen-activated protein kinase 13 | 3290 | 0.046 | 0.3657 | No |
| 10 | MAPK14 | MAPK14 Entrez, Source | mitogen-activated protein kinase 14 | 3543 | 0.042 | 0.3609 | No |
| 11 | PRKCH | PRKCH Entrez, Source | protein kinase C, eta | 3971 | 0.037 | 0.3411 | No |
| 12 | BCL2 | BCL2 Entrez, Source | B-cell CLL/lymphoma 2 | 4328 | 0.032 | 0.3251 | No |
| 13 | PRKCB1 | PRKCB1 Entrez, Source | protein kinase C, beta 1 | 4579 | 0.029 | 0.3160 | No |
| 14 | SP1 | SP1 Entrez, Source | Sp1 transcription factor | 5193 | 0.022 | 0.2772 | No |
| 15 | MAP2K6 | MAP2K6 Entrez, Source | mitogen-activated protein kinase kinase 6 | 6481 | 0.008 | 0.1831 | No |
| 16 | MAPK1 | MAPK1 Entrez, Source | mitogen-activated protein kinase 1 | 6633 | 0.006 | 0.1738 | No |
| 17 | TNF | TNF Entrez, Source | tumor necrosis factor (TNF superfamily, member 2) | 6778 | 0.004 | 0.1644 | No |
| 18 | PRKCA | PRKCA Entrez, Source | protein kinase C, alpha | 7310 | -0.002 | 0.1251 | No |
| 19 | PPP2CA | PPP2CA Entrez, Source | protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform | 7638 | -0.005 | 0.1022 | No |
| 20 | JUN | JUN Entrez, Source | jun oncogene | 8081 | -0.010 | 0.0725 | No |
| 21 | MAP2K1 | MAP2K1 Entrez, Source | mitogen-activated protein kinase kinase 1 | 8219 | -0.012 | 0.0662 | No |
| 22 | DAXX | DAXX Entrez, Source | death-associated protein 6 | 8710 | -0.018 | 0.0354 | No |
| 23 | HRAS | HRAS Entrez, Source | v-Ha-ras Harvey rat sarcoma viral oncogene homolog | 9267 | -0.025 | 0.0022 | No |
| 24 | MAP2K4 | MAP2K4 Entrez, Source | mitogen-activated protein kinase kinase 4 | 10315 | -0.042 | -0.0626 | No |
| 25 | NFKBIA | NFKBIA Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 10388 | -0.043 | -0.0535 | No |
| 26 | MAP3K1 | MAP3K1 Entrez, Source | mitogen-activated protein kinase kinase kinase 1 | 10643 | -0.048 | -0.0566 | No |
| 27 | RELA | RELA Entrez, Source | v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian) | 11138 | -0.059 | -0.0740 | No |
| 28 | MAP2K3 | MAP2K3 Entrez, Source | mitogen-activated protein kinase kinase 3 | 11186 | -0.060 | -0.0575 | No |
| 29 | NFKB1 | NFKB1 Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) | 11510 | -0.069 | -0.0588 | No |
| 30 | PRKCD | PRKCD Entrez, Source | protein kinase C, delta | 12535 | -0.120 | -0.0955 | No |
| 31 | IKBKB | IKBKB Entrez, Source | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | 12540 | -0.121 | -0.0555 | No |
| 32 | MAPK3 | MAPK3 Entrez, Source | mitogen-activated protein kinase 3 | 12674 | -0.132 | -0.0215 | No |
| 33 | ETS1 | ETS1 Entrez, Source | v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) | 13063 | -0.214 | 0.0210 | No |
