Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | LEE_ACOX1_DN |
| Enrichment Score (ES) | 0.4635964 |
| Normalized Enrichment Score (NES) | 1.6436616 |
| Nominal p-value | 0.005141388 |
| FDR q-value | 0.08127905 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SLC27A5 | SLC27A5 Entrez, Source | solute carrier family 27 (fatty acid transporter), member 5 | 12 | 0.395 | 0.0678 | Yes |
| 2 | G6PC | G6PC Entrez, Source | glucose-6-phosphatase, catalytic subunit | 26 | 0.337 | 0.1255 | Yes |
| 3 | SLCO2B1 | SLCO2B1 Entrez, Source | solute carrier organic anion transporter family, member 2B1 | 38 | 0.299 | 0.1767 | Yes |
| 4 | PPP1R3C | PPP1R3C Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 3C | 40 | 0.295 | 0.2279 | Yes |
| 5 | C4BPA | C4BPA Entrez, Source | complement component 4 binding protein, alpha | 79 | 0.243 | 0.2673 | Yes |
| 6 | TDO2 | TDO2 Entrez, Source | tryptophan 2,3-dioxygenase | 133 | 0.199 | 0.2979 | Yes |
| 7 | KHK | KHK Entrez, Source | ketohexokinase (fructokinase) | 161 | 0.189 | 0.3288 | Yes |
| 8 | OTC | OTC Entrez, Source | ornithine carbamoyltransferase | 183 | 0.178 | 0.3581 | Yes |
| 9 | GOT1 | GOT1 Entrez, Source | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 197 | 0.173 | 0.3872 | Yes |
| 10 | HSD11B1 | HSD11B1 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 1 | 318 | 0.147 | 0.4038 | Yes |
| 11 | SLC37A4 | SLC37A4 Entrez, Source | solute carrier family 37 (glycerol-6-phosphate transporter), member 4 | 368 | 0.139 | 0.4243 | Yes |
| 12 | SFTPD | SFTPD Entrez, Source | surfactant, pulmonary-associated protein D | 447 | 0.130 | 0.4410 | Yes |
| 13 | HGD | HGD Entrez, Source | homogentisate 1,2-dioxygenase (homogentisate oxidase) | 457 | 0.129 | 0.4628 | Yes |
| 14 | HAL | HAL Entrez, Source | histidine ammonia-lyase | 705 | 0.112 | 0.4636 | Yes |
| 15 | NR1H3 | NR1H3 Entrez, Source | nuclear receptor subfamily 1, group H, member 3 | 1041 | 0.096 | 0.4550 | No |
| 16 | PAH | PAH Entrez, Source | phenylalanine hydroxylase | 1513 | 0.079 | 0.4333 | No |
| 17 | BAAT | BAAT Entrez, Source | bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase) | 1625 | 0.077 | 0.4383 | No |
| 18 | ELA2 | ELA2 Entrez, Source | elastase 2, neutrophil | 1838 | 0.071 | 0.4348 | No |
| 19 | CYP4F2 | CYP4F2 Entrez, Source | cytochrome P450, family 4, subfamily F, polypeptide 2 | 2291 | 0.062 | 0.4116 | No |
| 20 | TNNT3 | TNNT3 Entrez, Source | troponin T type 3 (skeletal, fast) | 2298 | 0.062 | 0.4219 | No |
| 21 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 2688 | 0.055 | 0.4023 | No |
| 22 | ATP2A1 | ATP2A1 Entrez, Source | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 | 2732 | 0.055 | 0.4086 | No |
| 23 | GSTA3 | GSTA3 Entrez, Source | glutathione S-transferase A3 | 2795 | 0.053 | 0.4132 | No |
| 24 | SERPINA1 | SERPINA1 Entrez, Source | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 2824 | 0.053 | 0.4203 | No |
| 25 | AKAP11 | AKAP11 Entrez, Source | A kinase (PRKA) anchor protein 11 | 2841 | 0.053 | 0.4282 | No |
| 26 | PHLDA1 | PHLDA1 Entrez, Source | pleckstrin homology-like domain, family A, member 1 | 2920 | 0.051 | 0.4313 | No |
| 27 | PRODH | PRODH Entrez, Source | proline dehydrogenase (oxidase) 1 | 4210 | 0.034 | 0.3402 | No |
| 28 | CYP26A1 | CYP26A1 Entrez, Source | cytochrome P450, family 26, subfamily A, polypeptide 1 | 4758 | 0.027 | 0.3037 | No |
| 29 | MYH1 | MYH1 Entrez, Source | myosin, heavy chain 1, skeletal muscle, adult | 5231 | 0.021 | 0.2719 | No |
| 30 | MASP1 | MASP1 Entrez, Source | mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) | 5355 | 0.020 | 0.2660 | No |
| 31 | CPOX | CPOX Entrez, Source | coproporphyrinogen oxidase | 7776 | -0.007 | 0.0852 | No |
| 32 | OAT | OAT Entrez, Source | ornithine aminotransferase (gyrate atrophy) | 8046 | -0.010 | 0.0667 | No |
| 33 | HPD | HPD Entrez, Source | 4-hydroxyphenylpyruvate dioxygenase | 8248 | -0.012 | 0.0538 | No |
| 34 | DPP4 | DPP4 Entrez, Source | dipeptidyl-peptidase 4 (CD26, adenosine deaminase complexing protein 2) | 8651 | -0.017 | 0.0266 | No |
| 35 | MBL2 | MBL2 Entrez, Source | mannose-binding lectin (protein C) 2, soluble (opsonic defect) | 8903 | -0.021 | 0.0113 | No |
| 36 | HBP1 | HBP1 Entrez, Source | HMG-box transcription factor 1 | 8915 | -0.021 | 0.0140 | No |
| 37 | SLC29A1 | SLC29A1 Entrez, Source | solute carrier family 29 (nucleoside transporters), member 1 | 8957 | -0.021 | 0.0147 | No |
| 38 | CYP7B1 | CYP7B1 Entrez, Source | cytochrome P450, family 7, subfamily B, polypeptide 1 | 9803 | -0.033 | -0.0431 | No |
| 39 | GPR37 | GPR37 Entrez, Source | G protein-coupled receptor 37 (endothelin receptor type B-like) | 10305 | -0.041 | -0.0735 | No |
| 40 | RNASE4 | RNASE4 Entrez, Source | ribonuclease, RNase A family, 4 | 11851 | -0.081 | -0.1756 | No |
| 41 | SELENBP1 | SELENBP1 Entrez, Source | selenium binding protein 1 | 12740 | -0.140 | -0.2181 | No |
| 42 | NINJ1 | NINJ1 Entrez, Source | ninjurin 1 | 12752 | -0.141 | -0.1944 | No |
| 43 | IL1RAP | IL1RAP Entrez, Source | interleukin 1 receptor accessory protein | 12771 | -0.144 | -0.1707 | No |
| 44 | RGN | RGN Entrez, Source | regucalcin (senescence marker protein-30) | 13030 | -0.199 | -0.1555 | No |
| 45 | LIPC | LIPC Entrez, Source | lipase, hepatic | 13211 | -0.304 | -0.1162 | No |
| 46 | CA3 | CA3 Entrez, Source | carbonic anhydrase III, muscle specific | 13332 | -0.725 | 0.0008 | No |
