Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | LEE_E2F1_DN |
| Enrichment Score (ES) | 0.5734898 |
| Normalized Enrichment Score (NES) | 2.004547 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0057822503 |
| FWER p-Value | 0.177 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FABP1 | FABP1 Entrez, Source | fatty acid binding protein 1, liver | 10 | 0.411 | 0.0985 | Yes |
| 2 | C4BPA | C4BPA Entrez, Source | complement component 4 binding protein, alpha | 79 | 0.243 | 0.1519 | Yes |
| 3 | TDO2 | TDO2 Entrez, Source | tryptophan 2,3-dioxygenase | 133 | 0.199 | 0.1960 | Yes |
| 4 | PCK1 | PCK1 Entrez, Source | phosphoenolpyruvate carboxykinase 1 (soluble) | 148 | 0.193 | 0.2415 | Yes |
| 5 | OTC | OTC Entrez, Source | ornithine carbamoyltransferase | 183 | 0.178 | 0.2818 | Yes |
| 6 | GOT1 | GOT1 Entrez, Source | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 197 | 0.173 | 0.3226 | Yes |
| 7 | BHMT | BHMT Entrez, Source | betaine-homocysteine methyltransferase | 237 | 0.162 | 0.3588 | Yes |
| 8 | HSD11B1 | HSD11B1 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 1 | 318 | 0.147 | 0.3883 | Yes |
| 9 | PPCS | PPCS Entrez, Source | phosphopantothenoylcysteine synthetase | 340 | 0.143 | 0.4212 | Yes |
| 10 | ACSL1 | ACSL1 Entrez, Source | acyl-CoA synthetase long-chain family member 1 | 564 | 0.121 | 0.4336 | Yes |
| 11 | HAL | HAL Entrez, Source | histidine ammonia-lyase | 705 | 0.112 | 0.4500 | Yes |
| 12 | AQP8 | AQP8 Entrez, Source | aquaporin 8 | 728 | 0.110 | 0.4749 | Yes |
| 13 | ITPR1 | ITPR1 Entrez, Source | inositol 1,4,5-triphosphate receptor, type 1 | 1000 | 0.098 | 0.4780 | Yes |
| 14 | NR1H3 | NR1H3 Entrez, Source | nuclear receptor subfamily 1, group H, member 3 | 1041 | 0.096 | 0.4981 | Yes |
| 15 | CFH | CFH Entrez, Source | complement factor H | 1213 | 0.089 | 0.5068 | Yes |
| 16 | GHR | GHR Entrez, Source | growth hormone receptor | 1215 | 0.089 | 0.5282 | Yes |
| 17 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 1493 | 0.080 | 0.5266 | Yes |
| 18 | PXMP2 | PXMP2 Entrez, Source | peroxisomal membrane protein 2, 22kDa | 1591 | 0.077 | 0.5379 | Yes |
| 19 | BAAT | BAAT Entrez, Source | bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase) | 1625 | 0.077 | 0.5539 | Yes |
| 20 | ALDH1A1 | ALDH1A1 Entrez, Source | aldehyde dehydrogenase 1 family, member A1 | 1653 | 0.076 | 0.5701 | Yes |
| 21 | ELA2 | ELA2 Entrez, Source | elastase 2, neutrophil | 1838 | 0.071 | 0.5735 | Yes |
| 22 | PNLIP | PNLIP Entrez, Source | pancreatic lipase | 2144 | 0.065 | 0.5662 | No |
| 23 | RARRES1 | RARRES1 Entrez, Source | retinoic acid receptor responder (tazarotene induced) 1 | 2539 | 0.058 | 0.5505 | No |
| 24 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 2688 | 0.055 | 0.5528 | No |
| 25 | AKAP11 | AKAP11 Entrez, Source | A kinase (PRKA) anchor protein 11 | 2841 | 0.053 | 0.5540 | No |
| 26 | MDH1 | MDH1 Entrez, Source | malate dehydrogenase 1, NAD (soluble) | 2853 | 0.052 | 0.5658 | No |
| 27 | HADH2 | HADH2 Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase, type II | 3421 | 0.044 | 0.5338 | No |
| 28 | DBI | DBI Entrez, Source | diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein) | 3877 | 0.038 | 0.5089 | No |
| 29 | KYNU | KYNU Entrez, Source | kynureninase (L-kynurenine hydrolase) | 4061 | 0.035 | 0.5036 | No |
| 30 | IGF1 | IGF1 Entrez, Source | insulin-like growth factor 1 (somatomedin C) | 4345 | 0.032 | 0.4901 | No |
| 31 | ELOVL5 | ELOVL5 Entrez, Source | ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast) | 4382 | 0.032 | 0.4950 | No |
| 32 | GSTO1 | GSTO1 Entrez, Source | glutathione S-transferase omega 1 | 4785 | 0.026 | 0.4712 | No |
| 33 | SERPINF1 | SERPINF1 Entrez, Source | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 5398 | 0.019 | 0.4298 | No |
| 34 | ZG16 | ZG16 Entrez, Source | - | 6340 | 0.009 | 0.3613 | No |
| 35 | ADIPOR2 | ADIPOR2 Entrez, Source | adiponectin receptor 2 | 7084 | 0.001 | 0.3057 | No |
| 36 | OAT | OAT Entrez, Source | ornithine aminotransferase (gyrate atrophy) | 8046 | -0.010 | 0.2358 | No |
| 37 | PNLIPRP1 | PNLIPRP1 Entrez, Source | pancreatic lipase-related protein 1 | 8063 | -0.010 | 0.2371 | No |
| 38 | HPD | HPD Entrez, Source | 4-hydroxyphenylpyruvate dioxygenase | 8248 | -0.012 | 0.2262 | No |
| 39 | CYP2E1 | CYP2E1 Entrez, Source | cytochrome P450, family 2, subfamily E, polypeptide 1 | 10268 | -0.041 | 0.0842 | No |
| 40 | GPR37 | GPR37 Entrez, Source | G protein-coupled receptor 37 (endothelin receptor type B-like) | 10305 | -0.041 | 0.0915 | No |
| 41 | CTRC | CTRC Entrez, Source | chymotrypsin C (caldecrin) | 11080 | -0.058 | 0.0472 | No |
| 42 | ABCG2 | ABCG2 Entrez, Source | ATP-binding cassette, sub-family G (WHITE), member 2 | 11438 | -0.066 | 0.0363 | No |
| 43 | MAPKAPK2 | MAPKAPK2 Entrez, Source | mitogen-activated protein kinase-activated protein kinase 2 | 12240 | -0.099 | -0.0001 | No |
| 44 | IL1RAP | IL1RAP Entrez, Source | interleukin 1 receptor accessory protein | 12771 | -0.144 | -0.0051 | No |
| 45 | RGN | RGN Entrez, Source | regucalcin (senescence marker protein-30) | 13030 | -0.199 | 0.0235 | No |
