Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | LEE_MYC_DN |
| Enrichment Score (ES) | 0.68756354 |
| Normalized Enrichment Score (NES) | 2.3713658 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | G6PC | G6PC Entrez, Source | glucose-6-phosphatase, catalytic subunit | 26 | 0.337 | 0.0790 | Yes |
| 2 | C4BPA | C4BPA Entrez, Source | complement component 4 binding protein, alpha | 79 | 0.243 | 0.1334 | Yes |
| 3 | G0S2 | G0S2 Entrez, Source | G0/G1switch 2 | 98 | 0.228 | 0.1867 | Yes |
| 4 | TDO2 | TDO2 Entrez, Source | tryptophan 2,3-dioxygenase | 133 | 0.199 | 0.2320 | Yes |
| 5 | PCK1 | PCK1 Entrez, Source | phosphoenolpyruvate carboxykinase 1 (soluble) | 148 | 0.193 | 0.2773 | Yes |
| 6 | OTC | OTC Entrez, Source | ornithine carbamoyltransferase | 183 | 0.178 | 0.3173 | Yes |
| 7 | GOT1 | GOT1 Entrez, Source | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 197 | 0.173 | 0.3580 | Yes |
| 8 | FKBP5 | FKBP5 Entrez, Source | FK506 binding protein 5 | 219 | 0.169 | 0.3969 | Yes |
| 9 | BHMT | BHMT Entrez, Source | betaine-homocysteine methyltransferase | 237 | 0.162 | 0.4345 | Yes |
| 10 | RGS16 | RGS16 Entrez, Source | regulator of G-protein signalling 16 | 335 | 0.144 | 0.4618 | Yes |
| 11 | SLC37A4 | SLC37A4 Entrez, Source | solute carrier family 37 (glycerol-6-phosphate transporter), member 4 | 368 | 0.139 | 0.4927 | Yes |
| 12 | PFKFB1 | PFKFB1 Entrez, Source | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 | 476 | 0.127 | 0.5152 | Yes |
| 13 | HSPA5 | HSPA5 Entrez, Source | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 567 | 0.120 | 0.5373 | Yes |
| 14 | KLF15 | KLF15 Entrez, Source | Kruppel-like factor 15 | 600 | 0.118 | 0.5632 | Yes |
| 15 | HAL | HAL Entrez, Source | histidine ammonia-lyase | 705 | 0.112 | 0.5821 | Yes |
| 16 | HERPUD1 | HERPUD1 Entrez, Source | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 716 | 0.111 | 0.6080 | Yes |
| 17 | AQP8 | AQP8 Entrez, Source | aquaporin 8 | 728 | 0.110 | 0.6336 | Yes |
| 18 | DPYD | DPYD Entrez, Source | dihydropyrimidine dehydrogenase | 745 | 0.109 | 0.6586 | Yes |
| 19 | PCOLCE | PCOLCE Entrez, Source | procollagen C-endopeptidase enhancer | 798 | 0.107 | 0.6804 | Yes |
| 20 | CFH | CFH Entrez, Source | complement factor H | 1213 | 0.089 | 0.6707 | Yes |
| 21 | HRSP12 | HRSP12 Entrez, Source | heat-responsive protein 12 | 1267 | 0.087 | 0.6876 | Yes |
| 22 | FGG | FGG Entrez, Source | fibrinogen gamma chain | 1572 | 0.078 | 0.6834 | No |
| 23 | ELA2 | ELA2 Entrez, Source | elastase 2, neutrophil | 1838 | 0.071 | 0.6805 | No |
| 24 | PNLIP | PNLIP Entrez, Source | pancreatic lipase | 2144 | 0.065 | 0.6732 | No |
| 25 | DMBT1 | DMBT1 Entrez, Source | deleted in malignant brain tumors 1 | 2265 | 0.063 | 0.6793 | No |
| 26 | RARRES1 | RARRES1 Entrez, Source | retinoic acid receptor responder (tazarotene induced) 1 | 2539 | 0.058 | 0.6726 | No |
| 27 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 2688 | 0.055 | 0.6748 | No |
| 28 | EFEMP1 | EFEMP1 Entrez, Source | EGF-containing fibulin-like extracellular matrix protein 1 | 3166 | 0.048 | 0.6504 | No |
| 29 | IGFBP2 | IGFBP2 Entrez, Source | insulin-like growth factor binding protein 2, 36kDa | 3303 | 0.046 | 0.6511 | No |
| 30 | KYNU | KYNU Entrez, Source | kynureninase (L-kynurenine hydrolase) | 4061 | 0.035 | 0.6027 | No |
| 31 | IGF1 | IGF1 Entrez, Source | insulin-like growth factor 1 (somatomedin C) | 4345 | 0.032 | 0.5891 | No |
| 32 | ELOVL5 | ELOVL5 Entrez, Source | ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast) | 4382 | 0.032 | 0.5940 | No |
| 33 | MEOX2 | MEOX2 Entrez, Source | mesenchyme homeobox 2 | 5743 | 0.016 | 0.4955 | No |
| 34 | ZG16 | ZG16 Entrez, Source | - | 6340 | 0.009 | 0.4529 | No |
| 35 | SFXN1 | SFXN1 Entrez, Source | sideroflexin 1 | 6402 | 0.009 | 0.4503 | No |
| 36 | HSPH1 | HSPH1 Entrez, Source | heat shock 105kDa/110kDa protein 1 | 6870 | 0.003 | 0.4160 | No |
| 37 | IGF2 | IGF2 Entrez, Source | insulin-like growth factor 2 (somatomedin A) | 8017 | -0.010 | 0.3322 | No |
| 38 | PNLIPRP1 | PNLIPRP1 Entrez, Source | pancreatic lipase-related protein 1 | 8063 | -0.010 | 0.3313 | No |
| 39 | HBP1 | HBP1 Entrez, Source | HMG-box transcription factor 1 | 8915 | -0.021 | 0.2722 | No |
| 40 | IL1R1 | IL1R1 Entrez, Source | interleukin 1 receptor, type I | 10292 | -0.041 | 0.1787 | No |
| 41 | SATB1 | SATB1 Entrez, Source | special AT-rich sequence binding protein 1 (binds to nuclear matrix/scaffold-associating DNA's) | 10897 | -0.054 | 0.1461 | No |
| 42 | CTRC | CTRC Entrez, Source | chymotrypsin C (caldecrin) | 11080 | -0.058 | 0.1463 | No |
| 43 | MAPKAPK2 | MAPKAPK2 Entrez, Source | mitogen-activated protein kinase-activated protein kinase 2 | 12240 | -0.099 | 0.0829 | No |
