Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | LEE_MYC_E2F1_DN |
| Enrichment Score (ES) | 0.6283266 |
| Normalized Enrichment Score (NES) | 2.2065563 |
| Nominal p-value | 0.0 |
| FDR q-value | 4.9092824E-4 |
| FWER p-Value | 0.01 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FABP1 | FABP1 Entrez, Source | fatty acid binding protein 1, liver | 10 | 0.411 | 0.0857 | Yes |
| 2 | G6PC | G6PC Entrez, Source | glucose-6-phosphatase, catalytic subunit | 26 | 0.337 | 0.1555 | Yes |
| 3 | C4BPA | C4BPA Entrez, Source | complement component 4 binding protein, alpha | 79 | 0.243 | 0.2026 | Yes |
| 4 | G0S2 | G0S2 Entrez, Source | G0/G1switch 2 | 98 | 0.228 | 0.2492 | Yes |
| 5 | TDO2 | TDO2 Entrez, Source | tryptophan 2,3-dioxygenase | 133 | 0.199 | 0.2885 | Yes |
| 6 | PCK1 | PCK1 Entrez, Source | phosphoenolpyruvate carboxykinase 1 (soluble) | 148 | 0.193 | 0.3280 | Yes |
| 7 | OTC | OTC Entrez, Source | ornithine carbamoyltransferase | 183 | 0.178 | 0.3628 | Yes |
| 8 | GOT1 | GOT1 Entrez, Source | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 197 | 0.173 | 0.3982 | Yes |
| 9 | BHMT | BHMT Entrez, Source | betaine-homocysteine methyltransferase | 237 | 0.162 | 0.4294 | Yes |
| 10 | HSD11B1 | HSD11B1 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 1 | 318 | 0.147 | 0.4543 | Yes |
| 11 | MAT1A | MAT1A Entrez, Source | methionine adenosyltransferase I, alpha | 323 | 0.146 | 0.4847 | Yes |
| 12 | RGS16 | RGS16 Entrez, Source | regulator of G-protein signalling 16 | 335 | 0.144 | 0.5141 | Yes |
| 13 | SFTPD | SFTPD Entrez, Source | surfactant, pulmonary-associated protein D | 447 | 0.130 | 0.5331 | Yes |
| 14 | ACSL1 | ACSL1 Entrez, Source | acyl-CoA synthetase long-chain family member 1 | 564 | 0.121 | 0.5497 | Yes |
| 15 | EPHX2 | EPHX2 Entrez, Source | epoxide hydrolase 2, cytoplasmic | 660 | 0.114 | 0.5666 | Yes |
| 16 | HAL | HAL Entrez, Source | histidine ammonia-lyase | 705 | 0.112 | 0.5868 | Yes |
| 17 | TRPV2 | TRPV2 Entrez, Source | transient receptor potential cation channel, subfamily V, member 2 | 808 | 0.106 | 0.6015 | Yes |
| 18 | NR1H3 | NR1H3 Entrez, Source | nuclear receptor subfamily 1, group H, member 3 | 1041 | 0.096 | 0.6041 | Yes |
| 19 | GHR | GHR Entrez, Source | growth hormone receptor | 1215 | 0.089 | 0.6099 | Yes |
| 20 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 1493 | 0.080 | 0.6058 | Yes |
| 21 | PXMP2 | PXMP2 Entrez, Source | peroxisomal membrane protein 2, 22kDa | 1591 | 0.077 | 0.6147 | Yes |
| 22 | BAAT | BAAT Entrez, Source | bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase) | 1625 | 0.077 | 0.6283 | Yes |
| 23 | ELA2 | ELA2 Entrez, Source | elastase 2, neutrophil | 1838 | 0.071 | 0.6274 | No |
| 24 | CYP4F2 | CYP4F2 Entrez, Source | cytochrome P450, family 4, subfamily F, polypeptide 2 | 2291 | 0.062 | 0.6065 | No |
| 25 | RARRES1 | RARRES1 Entrez, Source | retinoic acid receptor responder (tazarotene induced) 1 | 2539 | 0.058 | 0.6001 | No |
| 26 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 2688 | 0.055 | 0.6006 | No |
| 27 | ALAD | ALAD Entrez, Source | aminolevulinate, delta-, dehydratase | 2787 | 0.054 | 0.6045 | No |
| 28 | IGFBP2 | IGFBP2 Entrez, Source | insulin-like growth factor binding protein 2, 36kDa | 3303 | 0.046 | 0.5753 | No |
| 29 | SLC25A22 | SLC25A22 Entrez, Source | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 | 3827 | 0.039 | 0.5442 | No |
| 30 | KYNU | KYNU Entrez, Source | kynureninase (L-kynurenine hydrolase) | 4061 | 0.035 | 0.5341 | No |
| 31 | IGF1 | IGF1 Entrez, Source | insulin-like growth factor 1 (somatomedin C) | 4345 | 0.032 | 0.5196 | No |
| 32 | ELOVL5 | ELOVL5 Entrez, Source | ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast) | 4382 | 0.032 | 0.5235 | No |
| 33 | ADIPOR2 | ADIPOR2 Entrez, Source | adiponectin receptor 2 | 7084 | 0.001 | 0.3206 | No |
| 34 | CPOX | CPOX Entrez, Source | coproporphyrinogen oxidase | 7776 | -0.007 | 0.2701 | No |
| 35 | OAT | OAT Entrez, Source | ornithine aminotransferase (gyrate atrophy) | 8046 | -0.010 | 0.2520 | No |
| 36 | PNLIPRP1 | PNLIPRP1 Entrez, Source | pancreatic lipase-related protein 1 | 8063 | -0.010 | 0.2529 | No |
| 37 | HPD | HPD Entrez, Source | 4-hydroxyphenylpyruvate dioxygenase | 8248 | -0.012 | 0.2417 | No |
| 38 | HBP1 | HBP1 Entrez, Source | HMG-box transcription factor 1 | 8915 | -0.021 | 0.1959 | No |
| 39 | FABP2 | FABP2 Entrez, Source | fatty acid binding protein 2, intestinal | 9006 | -0.022 | 0.1938 | No |
| 40 | CYP7B1 | CYP7B1 Entrez, Source | cytochrome P450, family 7, subfamily B, polypeptide 1 | 9803 | -0.033 | 0.1409 | No |
| 41 | CYP2E1 | CYP2E1 Entrez, Source | cytochrome P450, family 2, subfamily E, polypeptide 1 | 10268 | -0.041 | 0.1146 | No |
| 42 | ABCD3 | ABCD3 Entrez, Source | ATP-binding cassette, sub-family D (ALD), member 3 | 10872 | -0.053 | 0.0804 | No |
| 43 | CTRC | CTRC Entrez, Source | chymotrypsin C (caldecrin) | 11080 | -0.058 | 0.0770 | No |
| 44 | MAPKAPK2 | MAPKAPK2 Entrez, Source | mitogen-activated protein kinase-activated protein kinase 2 | 12240 | -0.099 | 0.0106 | No |
| 45 | IL1RAP | IL1RAP Entrez, Source | interleukin 1 receptor accessory protein | 12771 | -0.144 | 0.0010 | No |
| 46 | RGN | RGN Entrez, Source | regucalcin (senescence marker protein-30) | 13030 | -0.199 | 0.0235 | No |
