Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | LEE_MYC_TGFA_DN |
| Enrichment Score (ES) | 0.5749865 |
| Normalized Enrichment Score (NES) | 2.0643084 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0032607452 |
| FWER p-Value | 0.085 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FABP1 | FABP1 Entrez, Source | fatty acid binding protein 1, liver | 10 | 0.411 | 0.0585 | Yes |
| 2 | SLC27A5 | SLC27A5 Entrez, Source | solute carrier family 27 (fatty acid transporter), member 5 | 12 | 0.395 | 0.1153 | Yes |
| 3 | G6PC | G6PC Entrez, Source | glucose-6-phosphatase, catalytic subunit | 26 | 0.337 | 0.1629 | Yes |
| 4 | CA5A | CA5A Entrez, Source | carbonic anhydrase VA, mitochondrial | 32 | 0.310 | 0.2071 | Yes |
| 5 | C4BPA | C4BPA Entrez, Source | complement component 4 binding protein, alpha | 79 | 0.243 | 0.2387 | Yes |
| 6 | G0S2 | G0S2 Entrez, Source | G0/G1switch 2 | 98 | 0.228 | 0.2701 | Yes |
| 7 | TDO2 | TDO2 Entrez, Source | tryptophan 2,3-dioxygenase | 133 | 0.199 | 0.2963 | Yes |
| 8 | PCK1 | PCK1 Entrez, Source | phosphoenolpyruvate carboxykinase 1 (soluble) | 148 | 0.193 | 0.3230 | Yes |
| 9 | KHK | KHK Entrez, Source | ketohexokinase (fructokinase) | 161 | 0.189 | 0.3493 | Yes |
| 10 | OTC | OTC Entrez, Source | ornithine carbamoyltransferase | 183 | 0.178 | 0.3733 | Yes |
| 11 | GOT1 | GOT1 Entrez, Source | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 197 | 0.173 | 0.3973 | Yes |
| 12 | ACOX1 | ACOX1 Entrez, Source | acyl-Coenzyme A oxidase 1, palmitoyl | 227 | 0.165 | 0.4189 | Yes |
| 13 | BHMT | BHMT Entrez, Source | betaine-homocysteine methyltransferase | 237 | 0.162 | 0.4416 | Yes |
| 14 | ABAT | ABAT Entrez, Source | 4-aminobutyrate aminotransferase | 271 | 0.155 | 0.4613 | Yes |
| 15 | HSD11B1 | HSD11B1 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 1 | 318 | 0.147 | 0.4791 | Yes |
| 16 | RGS16 | RGS16 Entrez, Source | regulator of G-protein signalling 16 | 335 | 0.144 | 0.4986 | Yes |
| 17 | IGFALS | IGFALS Entrez, Source | insulin-like growth factor binding protein, acid labile subunit | 500 | 0.125 | 0.5042 | Yes |
| 18 | KLF15 | KLF15 Entrez, Source | Kruppel-like factor 15 | 600 | 0.118 | 0.5137 | Yes |
| 19 | EPHX2 | EPHX2 Entrez, Source | epoxide hydrolase 2, cytoplasmic | 660 | 0.114 | 0.5258 | Yes |
| 20 | HAL | HAL Entrez, Source | histidine ammonia-lyase | 705 | 0.112 | 0.5385 | Yes |
| 21 | AQP8 | AQP8 Entrez, Source | aquaporin 8 | 728 | 0.110 | 0.5528 | Yes |
| 22 | TRPV2 | TRPV2 Entrez, Source | transient receptor potential cation channel, subfamily V, member 2 | 808 | 0.106 | 0.5622 | Yes |
| 23 | CPT2 | CPT2 Entrez, Source | carnitine palmitoyltransferase II | 840 | 0.105 | 0.5750 | Yes |
| 24 | NR1H3 | NR1H3 Entrez, Source | nuclear receptor subfamily 1, group H, member 3 | 1041 | 0.096 | 0.5737 | No |
| 25 | PXMP2 | PXMP2 Entrez, Source | peroxisomal membrane protein 2, 22kDa | 1591 | 0.077 | 0.5436 | No |
| 26 | CMAH | CMAH Entrez, Source | cytidine monophosphate-N-acetylneuraminic acid hydroxylase (CMP-N-acetylneuraminate monooxygenase) | 1616 | 0.077 | 0.5528 | No |
| 27 | BAAT | BAAT Entrez, Source | bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase) | 1625 | 0.077 | 0.5632 | No |
| 28 | ALDH1A1 | ALDH1A1 Entrez, Source | aldehyde dehydrogenase 1 family, member A1 | 1653 | 0.076 | 0.5721 | No |
| 29 | CYP4F2 | CYP4F2 Entrez, Source | cytochrome P450, family 4, subfamily F, polypeptide 2 | 2291 | 0.062 | 0.5331 | No |
| 30 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 2688 | 0.055 | 0.5113 | No |
| 31 | HLA-DMA | HLA-DMA Entrez, Source | major histocompatibility complex, class II, DM alpha | 2689 | 0.055 | 0.5193 | No |
| 32 | HADH2 | HADH2 Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase, type II | 3421 | 0.044 | 0.4707 | No |
| 33 | SLC25A22 | SLC25A22 Entrez, Source | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 | 3827 | 0.039 | 0.4458 | No |
| 34 | KYNU | KYNU Entrez, Source | kynureninase (L-kynurenine hydrolase) | 4061 | 0.035 | 0.4334 | No |
| 35 | IGF1 | IGF1 Entrez, Source | insulin-like growth factor 1 (somatomedin C) | 4345 | 0.032 | 0.4167 | No |
| 36 | ELOVL5 | ELOVL5 Entrez, Source | ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast) | 4382 | 0.032 | 0.4186 | No |
| 37 | OAT | OAT Entrez, Source | ornithine aminotransferase (gyrate atrophy) | 8046 | -0.010 | 0.1444 | No |
| 38 | HPD | HPD Entrez, Source | 4-hydroxyphenylpyruvate dioxygenase | 8248 | -0.012 | 0.1311 | No |
| 39 | CRISP2 | CRISP2 Entrez, Source | cysteine-rich secretory protein 2 | 8445 | -0.015 | 0.1185 | No |
| 40 | ALAS2 | ALAS2 Entrez, Source | aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia) | 8816 | -0.019 | 0.0935 | No |
| 41 | FABP2 | FABP2 Entrez, Source | fatty acid binding protein 2, intestinal | 9006 | -0.022 | 0.0824 | No |
| 42 | CYP7B1 | CYP7B1 Entrez, Source | cytochrome P450, family 7, subfamily B, polypeptide 1 | 9803 | -0.033 | 0.0273 | No |
| 43 | GPR37 | GPR37 Entrez, Source | G protein-coupled receptor 37 (endothelin receptor type B-like) | 10305 | -0.041 | -0.0044 | No |
| 44 | ABCG2 | ABCG2 Entrez, Source | ATP-binding cassette, sub-family G (WHITE), member 2 | 11438 | -0.066 | -0.0800 | No |
| 45 | PSEN2 | PSEN2 Entrez, Source | presenilin 2 (Alzheimer disease 4) | 11726 | -0.076 | -0.0906 | No |
| 46 | MAPKAPK2 | MAPKAPK2 Entrez, Source | mitogen-activated protein kinase-activated protein kinase 2 | 12240 | -0.099 | -0.1150 | No |
| 47 | IL1RAP | IL1RAP Entrez, Source | interleukin 1 receptor accessory protein | 12771 | -0.144 | -0.1341 | No |
| 48 | RGN | RGN Entrez, Source | regucalcin (senescence marker protein-30) | 13030 | -0.199 | -0.1248 | No |
| 49 | LIPC | LIPC Entrez, Source | lipase, hepatic | 13211 | -0.304 | -0.0946 | No |
| 50 | CA3 | CA3 Entrez, Source | carbonic anhydrase III, muscle specific | 13332 | -0.725 | 0.0008 | No |
