Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | LEE_MYC_TGFA_UP |
| Enrichment Score (ES) | -0.5880156 |
| Normalized Enrichment Score (NES) | -1.8547662 |
| Nominal p-value | 0.0032948928 |
| FDR q-value | 0.03169725 |
| FWER p-Value | 0.845 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | TFRC | TFRC Entrez, Source | transferrin receptor (p90, CD71) | 439 | 0.131 | 0.0034 | No |
| 2 | IGFBP1 | IGFBP1 Entrez, Source | insulin-like growth factor binding protein 1 | 459 | 0.129 | 0.0377 | No |
| 3 | SLC13A3 | SLC13A3 Entrez, Source | solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 | 675 | 0.114 | 0.0531 | No |
| 4 | PSPH | PSPH Entrez, Source | phosphoserine phosphatase | 746 | 0.109 | 0.0781 | No |
| 5 | CSN3 | CSN3 Entrez, Source | casein kappa | 760 | 0.108 | 0.1072 | No |
| 6 | BTG2 | BTG2 Entrez, Source | BTG family, member 2 | 3927 | 0.037 | -0.1204 | No |
| 7 | MMP12 | MMP12 Entrez, Source | matrix metallopeptidase 12 (macrophage elastase) | 4861 | 0.026 | -0.1834 | No |
| 8 | ELF3 | ELF3 Entrez, Source | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 5740 | 0.016 | -0.2451 | No |
| 9 | CNN1 | CNN1 Entrez, Source | calponin 1, basic, smooth muscle | 6113 | 0.012 | -0.2698 | No |
| 10 | RPS24 | RPS24 Entrez, Source | ribosomal protein S24 | 6181 | 0.011 | -0.2717 | No |
| 11 | ATPIF1 | ATPIF1 Entrez, Source | ATPase inhibitory factor 1 | 6365 | 0.009 | -0.2830 | No |
| 12 | MT3 | MT3 Entrez, Source | metallothionein 3 (growth inhibitory factor (neurotrophic)) | 6558 | 0.007 | -0.2955 | No |
| 13 | LCN2 | LCN2 Entrez, Source | lipocalin 2 (oncogene 24p3) | 7114 | 0.001 | -0.3370 | No |
| 14 | TFF3 | TFF3 Entrez, Source | trefoil factor 3 (intestinal) | 7322 | -0.002 | -0.3521 | No |
| 15 | IGF2 | IGF2 Entrez, Source | insulin-like growth factor 2 (somatomedin A) | 8017 | -0.010 | -0.4016 | No |
| 16 | SLC1A4 | SLC1A4 Entrez, Source | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 | 8089 | -0.010 | -0.4040 | No |
| 17 | NT5E | NT5E Entrez, Source | 5'-nucleotidase, ecto (CD73) | 8154 | -0.011 | -0.4057 | No |
| 18 | ICAM1 | ICAM1 Entrez, Source | intercellular adhesion molecule 1 (CD54), human rhinovirus receptor | 8686 | -0.018 | -0.4407 | No |
| 19 | LPL | LPL Entrez, Source | lipoprotein lipase | 8894 | -0.020 | -0.4506 | No |
| 20 | GSTM1 | GSTM1 Entrez, Source | glutathione S-transferase M1 | 8992 | -0.022 | -0.4519 | No |
| 21 | CBR1 | CBR1 Entrez, Source | carbonyl reductase 1 | 10804 | -0.052 | -0.5737 | Yes |
| 22 | CD63 | CD63 Entrez, Source | CD63 molecule | 10826 | -0.052 | -0.5608 | Yes |
| 23 | BTG3 | BTG3 Entrez, Source | BTG family, member 3 | 11098 | -0.058 | -0.5651 | Yes |
| 24 | MFGE8 | MFGE8 Entrez, Source | milk fat globule-EGF factor 8 protein | 11250 | -0.061 | -0.5595 | Yes |
| 25 | IGFBP6 | IGFBP6 Entrez, Source | insulin-like growth factor binding protein 6 | 11430 | -0.066 | -0.5546 | Yes |
| 26 | NEDD9 | NEDD9 Entrez, Source | neural precursor cell expressed, developmentally down-regulated 9 | 11537 | -0.070 | -0.5432 | Yes |
| 27 | APP | APP Entrez, Source | amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease) | 11831 | -0.081 | -0.5429 | Yes |
| 28 | MGMT | MGMT Entrez, Source | O-6-methylguanine-DNA methyltransferase | 12359 | -0.108 | -0.5526 | Yes |
| 29 | CSTB | CSTB Entrez, Source | cystatin B (stefin B) | 12412 | -0.112 | -0.5255 | Yes |
| 30 | RAB3D | RAB3D Entrez, Source | RAB3D, member RAS oncogene family | 12543 | -0.121 | -0.5018 | Yes |
| 31 | USP18 | USP18 Entrez, Source | ubiquitin specific peptidase 18 | 12663 | -0.131 | -0.4744 | Yes |
| 32 | ANXA2 | ANXA2 Entrez, Source | annexin A2 | 12686 | -0.133 | -0.4391 | Yes |
| 33 | RALB | RALB Entrez, Source | v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) | 12865 | -0.159 | -0.4085 | Yes |
| 34 | PLSCR1 | PLSCR1 Entrez, Source | phospholipid scramblase 1 | 12879 | -0.161 | -0.3647 | Yes |
| 35 | GSTM2 | GSTM2 Entrez, Source | glutathione S-transferase M2 (muscle) | 12890 | -0.163 | -0.3202 | Yes |
| 36 | TAGLN2 | TAGLN2 Entrez, Source | transgelin 2 | 13110 | -0.236 | -0.2712 | Yes |
| 37 | PLAT | PLAT Entrez, Source | plasminogen activator, tissue | 13241 | -0.343 | -0.1858 | Yes |
| 38 | NDRG1 | NDRG1 Entrez, Source | N-myc downstream regulated gene 1 | 13242 | -0.345 | -0.0901 | Yes |
| 39 | CCND1 | CCND1 Entrez, Source | cyclin D1 | 13250 | -0.352 | 0.0069 | Yes |
