Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | LIGAND_DEPENDENT_NUCLEAR_RECEPTOR_ACTIVITY |
| Enrichment Score (ES) | 0.49653602 |
| Normalized Enrichment Score (NES) | 1.4467453 |
| Nominal p-value | 0.06849315 |
| FDR q-value | 0.17853503 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ESR2 | ESR2 Entrez, Source | estrogen receptor 2 (ER beta) | 144 | 0.195 | 0.1155 | Yes |
| 2 | NR1I3 | NR1I3 Entrez, Source | nuclear receptor subfamily 1, group I, member 3 | 153 | 0.191 | 0.2385 | Yes |
| 3 | PTGER3 | PTGER3 Entrez, Source | prostaglandin E receptor 3 (subtype EP3) | 244 | 0.161 | 0.3356 | Yes |
| 4 | RARB | RARB Entrez, Source | retinoic acid receptor, beta | 394 | 0.136 | 0.4125 | Yes |
| 5 | PGR | PGR Entrez, Source | progesterone receptor | 733 | 0.110 | 0.4582 | Yes |
| 6 | RXRA | RXRA Entrez, Source | retinoid X receptor, alpha | 1400 | 0.083 | 0.4616 | Yes |
| 7 | RXRG | RXRG Entrez, Source | retinoid X receptor, gamma | 2314 | 0.062 | 0.4330 | Yes |
| 8 | THRB | THRB Entrez, Source | thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian) | 2378 | 0.061 | 0.4675 | Yes |
| 9 | PPARD | PPARD Entrez, Source | peroxisome proliferative activated receptor, delta | 2558 | 0.058 | 0.4913 | Yes |
| 10 | AR | AR Entrez, Source | androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease) | 2931 | 0.051 | 0.4965 | Yes |
| 11 | THRA | THRA Entrez, Source | thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian) | 3546 | 0.042 | 0.4778 | No |
| 12 | RXRB | RXRB Entrez, Source | retinoid X receptor, beta | 3669 | 0.041 | 0.4950 | No |
| 13 | NR3C2 | NR3C2 Entrez, Source | nuclear receptor subfamily 3, group C, member 2 | 4947 | 0.025 | 0.4150 | No |
| 14 | PGRMC2 | PGRMC2 Entrez, Source | progesterone receptor membrane component 2 | 5345 | 0.020 | 0.3980 | No |
| 15 | RARA | RARA Entrez, Source | retinoic acid receptor, alpha | 5851 | 0.014 | 0.3694 | No |
| 16 | NR1D1 | NR1D1 Entrez, Source | nuclear receptor subfamily 1, group D, member 1 | 6058 | 0.012 | 0.3619 | No |
| 17 | VDR | VDR Entrez, Source | vitamin D (1,25- dihydroxyvitamin D3) receptor | 9079 | -0.023 | 0.1500 | No |
| 18 | NR2F6 | NR2F6 Entrez, Source | nuclear receptor subfamily 2, group F, member 6 | 10114 | -0.039 | 0.0974 | No |
| 19 | NR3C1 | NR3C1 Entrez, Source | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 10661 | -0.048 | 0.0876 | No |
| 20 | NR4A3 | NR4A3 Entrez, Source | nuclear receptor subfamily 4, group A, member 3 | 10905 | -0.054 | 0.1041 | No |
| 21 | BRD8 | BRD8 Entrez, Source | bromodomain containing 8 | 10958 | -0.055 | 0.1358 | No |
| 22 | AHR | AHR Entrez, Source | aryl hydrocarbon receptor | 11457 | -0.067 | 0.1415 | No |
