Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | LIGASE_ACTIVITY |
| Enrichment Score (ES) | 0.42942753 |
| Normalized Enrichment Score (NES) | 1.4882736 |
| Nominal p-value | 0.030162413 |
| FDR q-value | 0.15172836 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SLC27A5 | SLC27A5 Entrez, Source | solute carrier family 27 (fatty acid transporter), member 5 | 12 | 0.395 | 0.1578 | Yes |
| 2 | ACACA | ACACA Entrez, Source | acetyl-Coenzyme A carboxylase alpha | 157 | 0.190 | 0.2234 | Yes |
| 3 | CPS1 | CPS1 Entrez, Source | carbamoyl-phosphate synthetase 1, mitochondrial | 236 | 0.162 | 0.2827 | Yes |
| 4 | PC | PC Entrez, Source | pyruvate carboxylase | 270 | 0.155 | 0.3424 | Yes |
| 5 | ACSL1 | ACSL1 Entrez, Source | acyl-CoA synthetase long-chain family member 1 | 564 | 0.121 | 0.3688 | Yes |
| 6 | GCLC | GCLC Entrez, Source | glutamate-cysteine ligase, catalytic subunit | 1237 | 0.088 | 0.3537 | Yes |
| 7 | TRIM23 | TRIM23 Entrez, Source | tripartite motif-containing 23 | 1324 | 0.085 | 0.3815 | Yes |
| 8 | MTHFD1 | MTHFD1 Entrez, Source | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | 1392 | 0.083 | 0.4098 | Yes |
| 9 | UBE2D2 | UBE2D2 Entrez, Source | ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) | 1670 | 0.075 | 0.4191 | Yes |
| 10 | YARS | YARS Entrez, Source | tyrosyl-tRNA synthetase | 1907 | 0.070 | 0.4294 | Yes |
| 11 | PARK2 | PARK2 Entrez, Source | Parkinson disease (autosomal recessive, juvenile) 2, parkin | 3356 | 0.045 | 0.3386 | No |
| 12 | ACSL4 | ACSL4 Entrez, Source | acyl-CoA synthetase long-chain family member 4 | 3359 | 0.045 | 0.3566 | No |
| 13 | WWP1 | WWP1 Entrez, Source | WW domain containing E3 ubiquitin protein ligase 1 | 3459 | 0.044 | 0.3666 | No |
| 14 | FBXO22 | FBXO22 Entrez, Source | F-box protein 22 | 3590 | 0.042 | 0.3737 | No |
| 15 | PCCB | PCCB Entrez, Source | propionyl Coenzyme A carboxylase, beta polypeptide | 4212 | 0.034 | 0.3405 | No |
| 16 | GSS | GSS Entrez, Source | glutathione synthetase | 4963 | 0.024 | 0.2938 | No |
| 17 | GMPS | GMPS Entrez, Source | guanine monphosphate synthetase | 5619 | 0.017 | 0.2513 | No |
| 18 | NARS | NARS Entrez, Source | asparaginyl-tRNA synthetase | 5787 | 0.015 | 0.2448 | No |
| 19 | CTPS2 | CTPS2 Entrez, Source | CTP synthase II | 5797 | 0.015 | 0.2502 | No |
| 20 | GARS | GARS Entrez, Source | glycyl-tRNA synthetase | 5929 | 0.014 | 0.2458 | No |
| 21 | GCLM | GCLM Entrez, Source | glutamate-cysteine ligase, modifier subunit | 6039 | 0.012 | 0.2426 | No |
| 22 | RNF14 | RNF14 Entrez, Source | ring finger protein 14 | 6277 | 0.010 | 0.2288 | No |
| 23 | DARS | DARS Entrez, Source | aspartyl-tRNA synthetase | 6355 | 0.009 | 0.2266 | No |
| 24 | FBXO7 | FBXO7 Entrez, Source | F-box protein 7 | 6379 | 0.009 | 0.2284 | No |
| 25 | SYVN1 | SYVN1 Entrez, Source | synovial apoptosis inhibitor 1, synoviolin | 6805 | 0.004 | 0.1981 | No |
| 26 | KARS | KARS Entrez, Source | lysyl-tRNA synthetase | 6885 | 0.003 | 0.1934 | No |
| 27 | ASNS | ASNS Entrez, Source | asparagine synthetase | 7614 | -0.005 | 0.1407 | No |
| 28 | VARS | VARS Entrez, Source | valyl-tRNA synthetase | 7781 | -0.007 | 0.1309 | No |
| 29 | STUB1 | STUB1 Entrez, Source | STIP1 homology and U-box containing protein 1 | 7883 | -0.008 | 0.1266 | No |
| 30 | UBE2D3 | UBE2D3 Entrez, Source | ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) | 7926 | -0.009 | 0.1269 | No |
| 31 | ARIH1 | ARIH1 Entrez, Source | ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila) | 8193 | -0.012 | 0.1116 | No |
| 32 | UBE2L6 | UBE2L6 Entrez, Source | ubiquitin-conjugating enzyme E2L 6 | 8567 | -0.016 | 0.0901 | No |
| 33 | BTD | BTD Entrez, Source | biotinidase | 8580 | -0.017 | 0.0958 | No |
| 34 | ANAPC4 | ANAPC4 Entrez, Source | anaphase promoting complex subunit 4 | 9241 | -0.025 | 0.0562 | No |
| 35 | RTCD1 | RTCD1 Entrez, Source | RNA terminal phosphate cyclase domain 1 | 9372 | -0.027 | 0.0573 | No |
| 36 | FARS2 | FARS2 Entrez, Source | phenylalanine-tRNA synthetase 2 (mitochondrial) | 9474 | -0.029 | 0.0612 | No |
| 37 | PAICS | PAICS Entrez, Source | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | 10082 | -0.038 | 0.0309 | No |
| 38 | FBXO2 | FBXO2 Entrez, Source | F-box protein 2 | 10462 | -0.045 | 0.0203 | No |
| 39 | XRCC4 | XRCC4 Entrez, Source | X-ray repair complementing defective repair in Chinese hamster cells 4 | 10893 | -0.053 | 0.0094 | No |
| 40 | CDC23 | CDC23 Entrez, Source | CDC23 (cell division cycle 23, yeast, homolog) | 11864 | -0.082 | -0.0308 | No |
| 41 | ANAPC2 | ANAPC2 Entrez, Source | anaphase promoting complex subunit 2 | 12308 | -0.104 | -0.0224 | No |
| 42 | FBXL6 | FBXL6 Entrez, Source | F-box and leucine-rich repeat protein 6 | 12411 | -0.112 | 0.0148 | No |
| 43 | BIRC3 | BIRC3 Entrez, Source | baculoviral IAP repeat-containing 3 | 12722 | -0.137 | 0.0466 | No |
