Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | LI_FETAL_VS_WT_KIDNEY_DN |
| Enrichment Score (ES) | -0.4847588 |
| Normalized Enrichment Score (NES) | -1.7355875 |
| Nominal p-value | 0.0015479876 |
| FDR q-value | 0.052691564 |
| FWER p-Value | 0.999 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | LRP4 | LRP4 Entrez, Source | low density lipoprotein receptor-related protein 4 | 331 | 0.145 | -0.0033 | No |
| 2 | FADS2 | FADS2 Entrez, Source | fatty acid desaturase 2 | 362 | 0.140 | 0.0156 | No |
| 3 | SLC16A1 | SLC16A1 Entrez, Source | solute carrier family 16, member 1 (monocarboxylic acid transporter 1) | 376 | 0.138 | 0.0354 | No |
| 4 | NOLC1 | NOLC1 Entrez, Source | nucleolar and coiled-body phosphoprotein 1 | 1353 | 0.084 | -0.0256 | No |
| 5 | HMGA2 | HMGA2 Entrez, Source | high mobility group AT-hook 2 | 1533 | 0.079 | -0.0274 | No |
| 6 | SIX1 | SIX1 Entrez, Source | sine oculis homeobox homolog 1 (Drosophila) | 1834 | 0.071 | -0.0393 | No |
| 7 | YARS | YARS Entrez, Source | tyrosyl-tRNA synthetase | 1907 | 0.070 | -0.0342 | No |
| 8 | FADS1 | FADS1 Entrez, Source | fatty acid desaturase 1 | 1932 | 0.070 | -0.0256 | No |
| 9 | LIG3 | LIG3 Entrez, Source | ligase III, DNA, ATP-dependent | 2002 | 0.068 | -0.0205 | No |
| 10 | CRABP2 | CRABP2 Entrez, Source | cellular retinoic acid binding protein 2 | 2038 | 0.067 | -0.0131 | No |
| 11 | CDH2 | CDH2 Entrez, Source | cadherin 2, type 1, N-cadherin (neuronal) | 2163 | 0.065 | -0.0128 | No |
| 12 | UNG | UNG Entrez, Source | uracil-DNA glycosylase | 2374 | 0.061 | -0.0195 | No |
| 13 | ST6GAL1 | ST6GAL1 Entrez, Source | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | 2963 | 0.051 | -0.0562 | No |
| 14 | SPAG5 | SPAG5 Entrez, Source | sperm associated antigen 5 | 3211 | 0.047 | -0.0678 | No |
| 15 | BAZ1B | BAZ1B Entrez, Source | bromodomain adjacent to zinc finger domain, 1B | 3337 | 0.045 | -0.0705 | No |
| 16 | TXNRD1 | TXNRD1 Entrez, Source | thioredoxin reductase 1 | 3342 | 0.045 | -0.0640 | No |
| 17 | SHMT2 | SHMT2 Entrez, Source | serine hydroxymethyltransferase 2 (mitochondrial) | 3728 | 0.040 | -0.0870 | No |
| 18 | SRPK1 | SRPK1 Entrez, Source | SFRS protein kinase 1 | 3928 | 0.037 | -0.0964 | No |
| 19 | ABCA2 | ABCA2 Entrez, Source | ATP-binding cassette, sub-family A (ABC1), member 2 | 4027 | 0.036 | -0.0984 | No |
| 20 | ACP1 | ACP1 Entrez, Source | acid phosphatase 1, soluble | 4064 | 0.035 | -0.0958 | No |
| 21 | SMC4 | SMC4 Entrez, Source | structural maintenance of chromosomes 4 | 4217 | 0.034 | -0.1022 | No |
| 22 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 4258 | 0.033 | -0.1002 | No |
| 23 | CACNB3 | CACNB3 Entrez, Source | calcium channel, voltage-dependent, beta 3 subunit | 4260 | 0.033 | -0.0953 | No |
| 24 | CDKN3 | CDKN3 Entrez, Source | cyclin-dependent kinase inhibitor 3 (CDK2-associated dual specificity phosphatase) | 4303 | 0.033 | -0.0936 | No |
| 25 | DDX1 | DDX1 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 | 4387 | 0.031 | -0.0952 | No |
| 26 | DKC1 | DKC1 Entrez, Source | dyskeratosis congenita 1, dyskerin | 4523 | 0.030 | -0.1009 | No |
| 27 | NELL2 | NELL2 Entrez, Source | NEL-like 2 (chicken) | 4580 | 0.029 | -0.1007 | No |
| 28 | CIT | CIT Entrez, Source | citron (rho-interacting, serine/threonine kinase 21) | 5375 | 0.020 | -0.1577 | No |
| 29 | NME1 | NME1 Entrez, Source | non-metastatic cells 1, protein (NM23A) expressed in | 5403 | 0.019 | -0.1568 | No |
| 30 | POLE3 | POLE3 Entrez, Source | polymerase (DNA directed), epsilon 3 (p17 subunit) | 5404 | 0.019 | -0.1539 | No |
| 31 | CCND2 | CCND2 Entrez, Source | cyclin D2 | 5771 | 0.015 | -0.1793 | No |
| 32 | GARS | GARS Entrez, Source | glycyl-tRNA synthetase | 5929 | 0.014 | -0.1891 | No |
| 33 | CCT3 | CCT3 Entrez, Source | chaperonin containing TCP1, subunit 3 (gamma) | 5954 | 0.013 | -0.1889 | No |
| 34 | COL2A1 | COL2A1 Entrez, Source | collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphyseal dysplasia, congenital) | 6063 | 0.012 | -0.1952 | No |
| 35 | STRAP | STRAP Entrez, Source | serine/threonine kinase receptor associated protein | 6206 | 0.011 | -0.2043 | No |
| 36 | SV2A | SV2A Entrez, Source | synaptic vesicle glycoprotein 2A | 6513 | 0.007 | -0.2262 | No |
| 37 | BUB3 | BUB3 Entrez, Source | BUB3 budding uninhibited by benzimidazoles 3 homolog (yeast) | 6706 | 0.005 | -0.2399 | No |
| 38 | CDC20 | CDC20 Entrez, Source | CDC20 cell division cycle 20 homolog (S. cerevisiae) | 6894 | 0.003 | -0.2536 | No |
| 39 | NUP188 | NUP188 Entrez, Source | nucleoporin 188kDa | 7054 | 0.001 | -0.2654 | No |
| 40 | ADIPOR2 | ADIPOR2 Entrez, Source | adiponectin receptor 2 | 7084 | 0.001 | -0.2674 | No |
| 41 | CDK2 | CDK2 Entrez, Source | cyclin-dependent kinase 2 | 7469 | -0.003 | -0.2958 | No |
| 42 | PPP2R2A | PPP2R2A Entrez, Source | protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform | 7540 | -0.004 | -0.3005 | No |
| 43 | ASNS | ASNS Entrez, Source | asparagine synthetase | 7614 | -0.005 | -0.3052 | No |
| 44 | XRCC5 | XRCC5 Entrez, Source | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining; Ku autoantigen, 80kDa) | 7688 | -0.006 | -0.3099 | No |
| 45 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 8337 | -0.013 | -0.3568 | No |
| 46 | FEN1 | FEN1 Entrez, Source | flap structure-specific endonuclease 1 | 8375 | -0.014 | -0.3575 | No |
| 47 | TIA1 | TIA1 Entrez, Source | TIA1 cytotoxic granule-associated RNA binding protein | 8510 | -0.016 | -0.3652 | No |
| 48 | SSRP1 | SSRP1 Entrez, Source | structure specific recognition protein 1 | 8553 | -0.016 | -0.3660 | No |
| 49 | IGSF4 | IGSF4 Entrez, Source | immunoglobulin superfamily, member 4 | 9136 | -0.024 | -0.4063 | No |
| 50 | SS18 | SS18 Entrez, Source | synovial sarcoma translocation, chromosome 18 | 9223 | -0.025 | -0.4091 | No |
| 51 | AURKA | AURKA Entrez, Source | aurora kinase A | 9722 | -0.032 | -0.4418 | No |
| 52 | GPC1 | GPC1 Entrez, Source | glypican 1 | 9818 | -0.034 | -0.4439 | No |
| 53 | NAP1L1 | NAP1L1 Entrez, Source | nucleosome assembly protein 1-like 1 | 9838 | -0.034 | -0.4403 | No |
| 54 | PCBP2 | PCBP2 Entrez, Source | poly(rC) binding protein 2 | 10046 | -0.038 | -0.4503 | No |
| 55 | TOP2A | TOP2A Entrez, Source | topoisomerase (DNA) II alpha 170kDa | 10131 | -0.039 | -0.4508 | No |
| 56 | CHST1 | CHST1 Entrez, Source | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 | 10266 | -0.041 | -0.4547 | No |
| 57 | YWHAZ | YWHAZ Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 10313 | -0.042 | -0.4519 | No |
| 58 | DDX52 | DDX52 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 | 10512 | -0.046 | -0.4600 | No |
| 59 | CXCR4 | CXCR4 Entrez, Source | chemokine (C-X-C motif) receptor 4 | 10564 | -0.046 | -0.4569 | No |
| 60 | PTTG1 | PTTG1 Entrez, Source | pituitary tumor-transforming 1 | 10625 | -0.047 | -0.4543 | No |
| 61 | FAM62A | FAM62A Entrez, Source | family with sequence similarity 62 (C2 domain containing), member A | 10756 | -0.051 | -0.4565 | No |
| 62 | PARP1 | PARP1 Entrez, Source | poly (ADP-ribose) polymerase family, member 1 | 10758 | -0.051 | -0.4490 | No |
| 63 | PRIM2A | PRIM2A Entrez, Source | primase, polypeptide 2A, 58kDa | 10779 | -0.051 | -0.4428 | No |
| 64 | CKAP5 | CKAP5 Entrez, Source | cytoskeleton associated protein 5 | 10855 | -0.053 | -0.4406 | No |
| 65 | CHN1 | CHN1 Entrez, Source | chimerin (chimaerin) 1 | 10953 | -0.055 | -0.4396 | No |
| 66 | TARBP2 | TARBP2 Entrez, Source | Tar (HIV-1) RNA binding protein 2 | 11281 | -0.062 | -0.4550 | No |
| 67 | BUB1B | BUB1B Entrez, Source | BUB1 budding uninhibited by benzimidazoles 1 homolog beta (yeast) | 11337 | -0.063 | -0.4496 | No |
| 68 | GTF3C2 | GTF3C2 Entrez, Source | general transcription factor IIIC, polypeptide 2, beta 110kDa | 11404 | -0.065 | -0.4448 | No |
| 69 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 11780 | -0.078 | -0.4614 | No |
| 70 | PRIM1 | PRIM1 Entrez, Source | primase, polypeptide 1, 49kDa | 12091 | -0.091 | -0.4711 | Yes |
| 71 | RNASEH2A | RNASEH2A Entrez, Source | ribonuclease H2, subunit A | 12160 | -0.095 | -0.4620 | Yes |
| 72 | KIFC1 | KIFC1 Entrez, Source | kinesin family member C1 | 12256 | -0.100 | -0.4541 | Yes |
| 73 | MSH2 | MSH2 Entrez, Source | mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | 12287 | -0.103 | -0.4410 | Yes |
| 74 | CCNB2 | CCNB2 Entrez, Source | cyclin B2 | 12396 | -0.111 | -0.4325 | Yes |
| 75 | BRCA1 | BRCA1 Entrez, Source | breast cancer 1, early onset | 12787 | -0.146 | -0.4400 | Yes |
| 76 | TRIP13 | TRIP13 Entrez, Source | thyroid hormone receptor interactor 13 | 12798 | -0.147 | -0.4187 | Yes |
| 77 | KIF2C | KIF2C Entrez, Source | kinesin family member 2C | 12895 | -0.164 | -0.4013 | Yes |
| 78 | SCRN1 | SCRN1 Entrez, Source | secernin 1 | 12993 | -0.186 | -0.3807 | Yes |
| 79 | TIMELESS | TIMELESS Entrez, Source | timeless homolog (Drosophila) | 13018 | -0.194 | -0.3533 | Yes |
| 80 | LMNB1 | LMNB1 Entrez, Source | lamin B1 | 13104 | -0.234 | -0.3246 | Yes |
| 81 | AURKB | AURKB Entrez, Source | aurora kinase B | 13237 | -0.335 | -0.2843 | Yes |
| 82 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 13294 | -0.447 | -0.2214 | Yes |
| 83 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13301 | -0.469 | -0.1514 | Yes |
| 84 | KIAA0101 | KIAA0101 Entrez, Source | KIAA0101 | 13316 | -0.512 | -0.0756 | Yes |
| 85 | PFKP | PFKP Entrez, Source | phosphofructokinase, platelet | 13318 | -0.516 | 0.0018 | Yes |
