Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | LI_FETAL_VS_WT_KIDNEY_UP |
| Enrichment Score (ES) | -0.49257275 |
| Normalized Enrichment Score (NES) | -1.8147961 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.039798547 |
| FWER p-Value | 0.949 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GNG11 | GNG11 Entrez, Source | guanine nucleotide binding protein (G protein), gamma 11 | 35 | 0.306 | 0.0255 | No |
| 2 | PPP1R3C | PPP1R3C Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 3C | 40 | 0.295 | 0.0523 | No |
| 3 | SC4MOL | SC4MOL Entrez, Source | sterol-C4-methyl oxidase-like | 90 | 0.236 | 0.0703 | No |
| 4 | SLC30A1 | SLC30A1 Entrez, Source | solute carrier family 30 (zinc transporter), member 1 | 263 | 0.156 | 0.0716 | No |
| 5 | ALDH6A1 | ALDH6A1 Entrez, Source | aldehyde dehydrogenase 6 family, member A1 | 314 | 0.148 | 0.0814 | No |
| 6 | SEPHS2 | SEPHS2 Entrez, Source | selenophosphate synthetase 2 | 356 | 0.141 | 0.0913 | No |
| 7 | SLC37A4 | SLC37A4 Entrez, Source | solute carrier family 37 (glycerol-6-phosphate transporter), member 4 | 368 | 0.139 | 0.1033 | No |
| 8 | LEPR | LEPR Entrez, Source | leptin receptor | 448 | 0.130 | 0.1092 | No |
| 9 | ACSL1 | ACSL1 Entrez, Source | acyl-CoA synthetase long-chain family member 1 | 564 | 0.121 | 0.1116 | No |
| 10 | APOM | APOM Entrez, Source | apolipoprotein M | 628 | 0.117 | 0.1176 | No |
| 11 | MERTK | MERTK Entrez, Source | c-mer proto-oncogene tyrosine kinase | 698 | 0.112 | 0.1226 | No |
| 12 | HERPUD1 | HERPUD1 Entrez, Source | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 716 | 0.111 | 0.1315 | No |
| 13 | IFIT1 | IFIT1 Entrez, Source | interferon-induced protein with tetratricopeptide repeats 1 | 750 | 0.109 | 0.1391 | No |
| 14 | HRSP12 | HRSP12 Entrez, Source | heat-responsive protein 12 | 1267 | 0.087 | 0.1081 | No |
| 15 | HPN | HPN Entrez, Source | hepsin (transmembrane protease, serine 1) | 1303 | 0.086 | 0.1133 | No |
| 16 | ALDH1A1 | ALDH1A1 Entrez, Source | aldehyde dehydrogenase 1 family, member A1 | 1653 | 0.076 | 0.0939 | No |
| 17 | VEGF | VEGF Entrez, Source | vascular endothelial growth factor | 1883 | 0.070 | 0.0830 | No |
| 18 | SLC22A5 | SLC22A5 Entrez, Source | solute carrier family 22 (organic cation transporter), member 5 | 1950 | 0.069 | 0.0844 | No |
| 19 | COL1A2 | COL1A2 Entrez, Source | collagen, type I, alpha 2 | 2001 | 0.068 | 0.0869 | No |
| 20 | TOB1 | TOB1 Entrez, Source | transducer of ERBB2, 1 | 2158 | 0.065 | 0.0811 | No |
| 21 | KDR | KDR Entrez, Source | kinase insert domain receptor (a type III receptor tyrosine kinase) | 2505 | 0.058 | 0.0603 | No |
| 22 | SPP1 | SPP1 Entrez, Source | secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) | 2593 | 0.057 | 0.0589 | No |
| 23 | MAGI2 | MAGI2 Entrez, Source | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 2940 | 0.051 | 0.0375 | No |
| 24 | CLDN3 | CLDN3 Entrez, Source | claudin 3 | 3133 | 0.048 | 0.0274 | No |
| 25 | TPST1 | TPST1 Entrez, Source | tyrosylprotein sulfotransferase 1 | 3134 | 0.048 | 0.0318 | No |
| 26 | FGF9 | FGF9 Entrez, Source | fibroblast growth factor 9 (glia-activating factor) | 3315 | 0.046 | 0.0224 | No |
| 27 | FPGT | FPGT Entrez, Source | fucose-1-phosphate guanylyltransferase | 3376 | 0.045 | 0.0220 | No |
| 28 | SEPP1 | SEPP1 Entrez, Source | selenoprotein P, plasma, 1 | 3423 | 0.044 | 0.0226 | No |
| 29 | PLAU | PLAU Entrez, Source | plasminogen activator, urokinase | 3505 | 0.043 | 0.0204 | No |
| 30 | SCP2 | SCP2 Entrez, Source | sterol carrier protein 2 | 3534 | 0.042 | 0.0222 | No |
| 31 | TCF21 | TCF21 Entrez, Source | transcription factor 21 | 3948 | 0.037 | -0.0056 | No |
| 32 | NCOA3 | NCOA3 Entrez, Source | nuclear receptor coactivator 3 | 4160 | 0.034 | -0.0184 | No |
| 33 | CEBPD | CEBPD Entrez, Source | CCAAT/enhancer binding protein (C/EBP), delta | 4223 | 0.034 | -0.0200 | No |
| 34 | ANK3 | ANK3 Entrez, Source | ankyrin 3, node of Ranvier (ankyrin G) | 4640 | 0.028 | -0.0488 | No |
| 35 | ACSM3 | ACSM3 Entrez, Source | acyl-CoA synthetase medium-chain family member 3 | 4653 | 0.028 | -0.0472 | No |
| 36 | GUCY1A3 | GUCY1A3 Entrez, Source | guanylate cyclase 1, soluble, alpha 3 | 4731 | 0.027 | -0.0505 | No |
| 37 | TGOLN2 | TGOLN2 Entrez, Source | trans-golgi network protein 2 | 4893 | 0.025 | -0.0603 | No |
| 38 | CDKN1C | CDKN1C Entrez, Source | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 5020 | 0.024 | -0.0677 | No |
| 39 | GADD45A | GADD45A Entrez, Source | growth arrest and DNA-damage-inducible, alpha | 5178 | 0.022 | -0.0776 | No |
| 40 | ZFHX1B | ZFHX1B Entrez, Source | zinc finger homeobox 1b | 5318 | 0.020 | -0.0862 | No |
| 41 | PGRMC2 | PGRMC2 Entrez, Source | progesterone receptor membrane component 2 | 5345 | 0.020 | -0.0864 | No |
| 42 | SERPINF1 | SERPINF1 Entrez, Source | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 5398 | 0.019 | -0.0885 | No |
| 43 | SDHD | SDHD Entrez, Source | succinate dehydrogenase complex, subunit D, integral membrane protein | 5418 | 0.019 | -0.0882 | No |
| 44 | XBP1 | XBP1 Entrez, Source | X-box binding protein 1 | 5608 | 0.017 | -0.1009 | No |
| 45 | TACSTD2 | TACSTD2 Entrez, Source | tumor-associated calcium signal transducer 2 | 5622 | 0.017 | -0.1004 | No |
| 46 | CDH1 | CDH1 Entrez, Source | cadherin 1, type 1, E-cadherin (epithelial) | 6086 | 0.012 | -0.1343 | No |
| 47 | ERG | ERG Entrez, Source | v-ets erythroblastosis virus E26 oncogene homolog (avian) | 6202 | 0.011 | -0.1419 | No |
| 48 | ATP1A1 | ATP1A1 Entrez, Source | ATPase, Na+/K+ transporting, alpha 1 polypeptide | 6356 | 0.009 | -0.1527 | No |
| 49 | CDS1 | CDS1 Entrez, Source | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 | 6414 | 0.008 | -0.1562 | No |
| 50 | FGFR3 | FGFR3 Entrez, Source | fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) | 6436 | 0.008 | -0.1570 | No |
| 51 | PMP22 | PMP22 Entrez, Source | peripheral myelin protein 22 | 6574 | 0.007 | -0.1668 | No |
| 52 | PDE8A | PDE8A Entrez, Source | phosphodiesterase 8A | 6686 | 0.006 | -0.1747 | No |
| 53 | BPGM | BPGM Entrez, Source | 2,3-bisphosphoglycerate mutase | 7240 | -0.001 | -0.2164 | No |
| 54 | APOE | APOE Entrez, Source | apolipoprotein E | 7411 | -0.003 | -0.2290 | No |
| 55 | CYB5A | CYB5A Entrez, Source | cytochrome b5 type A (microsomal) | 7424 | -0.003 | -0.2296 | No |
| 56 | ATP1B1 | ATP1B1 Entrez, Source | ATPase, Na+/K+ transporting, beta 1 polypeptide | 7708 | -0.006 | -0.2505 | No |
| 57 | PEX7 | PEX7 Entrez, Source | peroxisomal biogenesis factor 7 | 7894 | -0.008 | -0.2637 | No |
| 58 | PLCG2 | PLCG2 Entrez, Source | phospholipase C, gamma 2 (phosphatidylinositol-specific) | 8698 | -0.018 | -0.3227 | No |
| 59 | TMED5 | TMED5 Entrez, Source | transmembrane emp24 protein transport domain containing 5 | 8849 | -0.020 | -0.3322 | No |
| 60 | TFPI | TFPI Entrez, Source | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 8929 | -0.021 | -0.3363 | No |
| 61 | SLC35A3 | SLC35A3 Entrez, Source | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 8981 | -0.022 | -0.3382 | No |
| 62 | ST3GAL6 | ST3GAL6 Entrez, Source | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 9231 | -0.025 | -0.3547 | No |
| 63 | LAMP2 | LAMP2 Entrez, Source | lysosomal-associated membrane protein 2 | 9376 | -0.027 | -0.3631 | No |
| 64 | ITM2B | ITM2B Entrez, Source | integral membrane protein 2B | 9609 | -0.031 | -0.3778 | No |
| 65 | IL1R1 | IL1R1 Entrez, Source | interleukin 1 receptor, type I | 10292 | -0.041 | -0.4256 | No |
| 66 | CREBL2 | CREBL2 Entrez, Source | cAMP responsive element binding protein-like 2 | 10552 | -0.046 | -0.4409 | No |
| 67 | NR3C1 | NR3C1 Entrez, Source | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 10661 | -0.048 | -0.4446 | No |
| 68 | CTSH | CTSH Entrez, Source | cathepsin H | 11083 | -0.058 | -0.4711 | No |
| 69 | PPAP2A | PPAP2A Entrez, Source | phosphatidic acid phosphatase type 2A | 11084 | -0.058 | -0.4658 | No |
| 70 | SYNGR2 | SYNGR2 Entrez, Source | synaptogyrin 2 | 11245 | -0.061 | -0.4723 | No |
| 71 | AXL | AXL Entrez, Source | AXL receptor tyrosine kinase | 11348 | -0.064 | -0.4742 | No |
| 72 | PODXL | PODXL Entrez, Source | podocalyxin-like | 11359 | -0.064 | -0.4690 | No |
| 73 | FAM3C | FAM3C Entrez, Source | family with sequence similarity 3, member C | 11530 | -0.070 | -0.4755 | No |
| 74 | CAST | CAST Entrez, Source | calpastatin | 11630 | -0.073 | -0.4763 | No |
| 75 | CLU | CLU Entrez, Source | clusterin | 11686 | -0.075 | -0.4735 | No |
| 76 | ANGPT1 | ANGPT1 Entrez, Source | angiopoietin 1 | 11939 | -0.085 | -0.4848 | Yes |
| 77 | CX3CL1 | CX3CL1 Entrez, Source | chemokine (C-X3-C motif) ligand 1 | 11975 | -0.086 | -0.4795 | Yes |
| 78 | LYN | LYN Entrez, Source | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 12083 | -0.091 | -0.4793 | Yes |
| 79 | MYH9 | MYH9 Entrez, Source | myosin, heavy chain 9, non-muscle | 12120 | -0.093 | -0.4735 | Yes |
| 80 | CRYZ | CRYZ Entrez, Source | crystallin, zeta (quinone reductase) | 12135 | -0.093 | -0.4660 | Yes |
| 81 | PRPS2 | PRPS2 Entrez, Source | phosphoribosyl pyrophosphate synthetase 2 | 12137 | -0.093 | -0.4575 | Yes |
| 82 | PLS3 | PLS3 Entrez, Source | plastin 3 (T isoform) | 12156 | -0.094 | -0.4501 | Yes |
| 83 | TGFBR2 | TGFBR2 Entrez, Source | transforming growth factor, beta receptor II (70/80kDa) | 12175 | -0.096 | -0.4427 | Yes |
| 84 | TSPO | TSPO Entrez, Source | translocator protein (18kDa) | 12217 | -0.098 | -0.4368 | Yes |
| 85 | GNG12 | GNG12 Entrez, Source | guanine nucleotide binding protein (G protein), gamma 12 | 12245 | -0.099 | -0.4298 | Yes |
| 86 | S100A10 | S100A10 Entrez, Source | S100 calcium binding protein A10 | 12269 | -0.101 | -0.4222 | Yes |
| 87 | ENPEP | ENPEP Entrez, Source | glutamyl aminopeptidase (aminopeptidase A) | 12336 | -0.106 | -0.4175 | Yes |
| 88 | DYNC2LI1 | DYNC2LI1 Entrez, Source | dynein, cytoplasmic 2, light intermediate chain 1 | 12337 | -0.106 | -0.4077 | Yes |
| 89 | IMPA2 | IMPA2 Entrez, Source | inositol(myo)-1(or 4)-monophosphatase 2 | 12423 | -0.112 | -0.4038 | Yes |
| 90 | ANXA4 | ANXA4 Entrez, Source | annexin A4 | 12446 | -0.114 | -0.3950 | Yes |
| 91 | KIFC3 | KIFC3 Entrez, Source | kinesin family member C3 | 12529 | -0.120 | -0.3902 | Yes |
| 92 | ASAH1 | ASAH1 Entrez, Source | N-acylsphingosine amidohydrolase (acid ceramidase) 1 | 12530 | -0.120 | -0.3792 | Yes |
| 93 | ELF1 | ELF1 Entrez, Source | E74-like factor 1 (ets domain transcription factor) | 12637 | -0.129 | -0.3754 | Yes |
| 94 | SMPDL3A | SMPDL3A Entrez, Source | sphingomyelin phosphodiesterase, acid-like 3A | 12687 | -0.133 | -0.3668 | Yes |
| 95 | DSTN | DSTN Entrez, Source | destrin (actin depolymerizing factor) | 12710 | -0.136 | -0.3560 | Yes |
| 96 | TRIM2 | TRIM2 Entrez, Source | tripartite motif-containing 2 | 12840 | -0.154 | -0.3516 | Yes |
| 97 | ALCAM | ALCAM Entrez, Source | activated leukocyte cell adhesion molecule | 12991 | -0.186 | -0.3458 | Yes |
| 98 | AGRIN | AGRIN Entrez, Source | agrin | 13039 | -0.202 | -0.3308 | Yes |
| 99 | MAF | MAF Entrez, Source | v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) | 13083 | -0.223 | -0.3135 | Yes |
| 100 | PRNP | PRNP Entrez, Source | prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia) | 13090 | -0.227 | -0.2931 | Yes |
| 101 | UGCG | UGCG Entrez, Source | UDP-glucose ceramide glucosyltransferase | 13105 | -0.234 | -0.2727 | Yes |
| 102 | ANXA3 | ANXA3 Entrez, Source | annexin A3 | 13112 | -0.236 | -0.2514 | Yes |
| 103 | VLDLR | VLDLR Entrez, Source | very low density lipoprotein receptor | 13129 | -0.246 | -0.2300 | Yes |
| 104 | DAB2 | DAB2 Entrez, Source | disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) | 13130 | -0.247 | -0.2073 | Yes |
| 105 | CAV2 | CAV2 Entrez, Source | caveolin 2 | 13140 | -0.252 | -0.1848 | Yes |
| 106 | DUSP9 | DUSP9 Entrez, Source | dual specificity phosphatase 9 | 13170 | -0.271 | -0.1621 | Yes |
| 107 | CRYAB | CRYAB Entrez, Source | crystallin, alpha B | 13206 | -0.298 | -0.1374 | Yes |
| 108 | SERINC5 | SERINC5 Entrez, Source | serine incorporator 5 | 13209 | -0.303 | -0.1097 | Yes |
| 109 | GNAI1 | GNAI1 Entrez, Source | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 13239 | -0.335 | -0.0811 | Yes |
| 110 | IGFBP7 | IGFBP7 Entrez, Source | insulin-like growth factor binding protein 7 | 13304 | -0.474 | -0.0423 | Yes |
| 111 | AHNAK | AHNAK Entrez, Source | AHNAK nucleoprotein (desmoyokin) | 13311 | -0.491 | 0.0023 | Yes |
