Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | LOTEM_LEUKEMIA_UP |
| Enrichment Score (ES) | 0.6056064 |
| Normalized Enrichment Score (NES) | 1.6831965 |
| Nominal p-value | 0.015486726 |
| FDR q-value | 0.063320145 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | EGR2 | EGR2 Entrez, Source | early growth response 2 (Krox-20 homolog, Drosophila) | 66 | 0.256 | 0.2066 | Yes |
| 2 | LPIN1 | LPIN1 Entrez, Source | lipin 1 | 104 | 0.220 | 0.3859 | Yes |
| 3 | SNX10 | SNX10 Entrez, Source | sorting nexin 10 | 397 | 0.136 | 0.4765 | Yes |
| 4 | AK1 | AK1 Entrez, Source | adenylate kinase 1 | 1604 | 0.077 | 0.4497 | Yes |
| 5 | CCS | CCS Entrez, Source | copper chaperone for superoxide dismutase | 2069 | 0.066 | 0.4698 | Yes |
| 6 | CD53 | CD53 Entrez, Source | CD53 molecule | 2203 | 0.064 | 0.5127 | Yes |
| 7 | CP | CP Entrez, Source | ceruloplasmin (ferroxidase) | 2438 | 0.060 | 0.5446 | Yes |
| 8 | PTPRO | PTPRO Entrez, Source | protein tyrosine phosphatase, receptor type, O | 2452 | 0.059 | 0.5928 | Yes |
| 9 | LIFR | LIFR Entrez, Source | leukemia inhibitory factor receptor alpha | 2859 | 0.052 | 0.6056 | Yes |
| 10 | PPM1B | PPM1B Entrez, Source | protein phosphatase 1B (formerly 2C), magnesium-dependent, beta isoform | 6165 | 0.011 | 0.3669 | No |
| 11 | KPNA1 | KPNA1 Entrez, Source | karyopherin alpha 1 (importin alpha 5) | 6658 | 0.006 | 0.3348 | No |
| 12 | LYPLA1 | LYPLA1 Entrez, Source | lysophospholipase I | 7261 | -0.001 | 0.2903 | No |
| 13 | TAF9 | TAF9 Entrez, Source | TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa | 9217 | -0.025 | 0.1640 | No |
| 14 | PMM1 | PMM1 Entrez, Source | phosphomannomutase 1 | 9922 | -0.035 | 0.1402 | No |
| 15 | SH3GLB1 | SH3GLB1 Entrez, Source | SH3-domain GRB2-like endophilin B1 | 9998 | -0.037 | 0.1649 | No |
| 16 | SERPINI1 | SERPINI1 Entrez, Source | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | 10346 | -0.042 | 0.1738 | No |
| 17 | TAP1 | TAP1 Entrez, Source | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 11267 | -0.062 | 0.1557 | No |
