Details for gene set LYASE

Table: GSEA Results Summary

Dataset	double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos
Phenotype	class.cls#double_gel_48h_versus_single_gel_48h_repos
Upregulated in class	double_gel_48h
GeneSet	LYASE_ACTIVITY
Enrichment Score (ES)	0.503492
Normalized Enrichment Score (NES)	1.8167307
Nominal p-value	0.0
FDR q-value	0.027861608
FWER p-Value	0.856

Table: GSEA details [plain text format]
	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	EHHADH	EHHADH Entrez, Source	enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase	6	0.447	0.0958	Yes
2	MVD	MVD Entrez, Source	mevalonate (diphospho) decarboxylase	21	0.352	0.1706	Yes
3	CA5A	CA5A Entrez, Source	carbonic anhydrase VA, mitochondrial	32	0.310	0.2365	Yes
4	GUCY2C	GUCY2C Entrez, Source	guanylate cyclase 2C (heat stable enterotoxin receptor)	85	0.240	0.2843	Yes
5	HACL1	HACL1 Entrez, Source	2-hydroxyacyl-CoA lyase 1	94	0.229	0.3330	Yes
6	PCK1	PCK1 Entrez, Source	phosphoenolpyruvate carboxykinase 1 (soluble)	148	0.193	0.3706	Yes
7	ASL	ASL Entrez, Source	argininosuccinate lyase	273	0.154	0.3944	Yes
8	HDC	HDC Entrez, Source	histidine decarboxylase	383	0.138	0.4160	Yes
9	ACMSD	ACMSD Entrez, Source	aminocarboxymuconate semialdehyde decarboxylase	514	0.124	0.4329	Yes
10	PTS	PTS Entrez, Source	6-pyruvoyltetrahydropterin synthase	877	0.104	0.4280	Yes
11	ALDOB	ALDOB Entrez, Source	aldolase B, fructose-bisphosphate	941	0.100	0.4448	Yes
12	SCLY	SCLY Entrez, Source	selenocysteine lyase	1056	0.095	0.4567	Yes
13	CBS	CBS Entrez, Source	cystathionine-beta-synthase	1127	0.092	0.4712	Yes
14	CA4	CA4 Entrez, Source	carbonic anhydrase IV	1388	0.083	0.4696	Yes
15	GUCY1A2	GUCY1A2 Entrez, Source	guanylate cyclase 1, soluble, alpha 2	1492	0.080	0.4790	Yes
16	ECHS1	ECHS1 Entrez, Source	enoyl Coenzyme A hydratase, short chain, 1, mitochondrial	1528	0.079	0.4933	Yes
17	OGG1	OGG1 Entrez, Source	8-oxoguanine DNA glycosylase	1613	0.077	0.5035	Yes
18	BCKDHA	BCKDHA Entrez, Source	branched chain keto acid dehydrogenase E1, alpha polypeptide	2252	0.063	0.4691	No
19	MLYCD	MLYCD Entrez, Source	malonyl-CoA decarboxylase	2302	0.062	0.4787	No
20	GUCY2F	GUCY2F Entrez, Source	guanylate cyclase 2F, retinal	2753	0.054	0.4565	No
21	ENO2	ENO2 Entrez, Source	enolase 2 (gamma, neuronal)	2779	0.054	0.4662	No
22	ALAD	ALAD Entrez, Source	aminolevulinate, delta-, dehydratase	2787	0.054	0.4772	No
23	GMDS	GMDS Entrez, Source	GDP-mannose 4,6-dehydratase	2826	0.053	0.4858	No
24	GUCY1B3	GUCY1B3 Entrez, Source	guanylate cyclase 1, soluble, beta 3	3272	0.046	0.4622	No
25	SDS	SDS Entrez, Source	serine dehydratase	3684	0.041	0.4401	No
26	BCKDHB	BCKDHB Entrez, Source	branched chain keto acid dehydrogenase E1, beta polypeptide (maple syrup urine disease)	3912	0.038	0.4311	No
27	UMPS	UMPS Entrez, Source	uridine monophosphate synthetase (orotate phosphoribosyl transferase and orotidine-5'-decarboxylase)	4001	0.036	0.4323	No
28	GUCY2D	GUCY2D Entrez, Source	guanylate cyclase 2D, membrane (retina-specific)	4006	0.036	0.4398	No
29	APEX1	APEX1 Entrez, Source	APEX nuclease (multifunctional DNA repair enzyme) 1	4028	0.036	0.4460	No
30	HADHB	HADHB Entrez, Source	hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit	4313	0.032	0.4316	No
31	DDC	DDC Entrez, Source	dopa decarboxylase (aromatic L-amino acid decarboxylase)	4512	0.030	0.4232	No
32	ACO1	ACO1 Entrez, Source	aconitase 1, soluble	4655	0.028	0.4185	No
33	GUCY1A3	GUCY1A3 Entrez, Source	guanylate cyclase 1, soluble, alpha 3	4731	0.027	0.4187	No
34	HADHA	HADHA Entrez, Source	hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit	5156	0.022	0.3915	No
35	GAD1	GAD1 Entrez, Source	glutamate decarboxylase 1 (brain, 67kDa)	5455	0.019	0.3732	No
36	AMD1	AMD1 Entrez, Source	adenosylmethionine decarboxylase 1	5628	0.017	0.3638	No
37	GGCX	GGCX Entrez, Source	gamma-glutamyl carboxylase	5821	0.015	0.3526	No
38	ENO3	ENO3 Entrez, Source	enolase 3 (beta, muscle)	6328	0.009	0.3165	No
39	ALDOC	ALDOC Entrez, Source	aldolase C, fructose-bisphosphate	6404	0.008	0.3127	No
40	CA2	CA2 Entrez, Source	carbonic anhydrase II	7034	0.002	0.2657	No
41	CRYM	CRYM Entrez, Source	crystallin, mu	7438	-0.003	0.2361	No
42	ODC1	ODC1 Entrez, Source	ornithine decarboxylase 1	7596	-0.005	0.2253	No
43	CA5B	CA5B Entrez, Source	carbonic anhydrase VB, mitochondrial	7888	-0.008	0.2051	No
44	LTC4S	LTC4S Entrez, Source	leukotriene C4 synthase	7935	-0.009	0.2036	No
45	ECH1	ECH1 Entrez, Source	enoyl Coenzyme A hydratase 1, peroxisomal	8150	-0.011	0.1899	No
46	ADCY10			8656	-0.018	0.1556	No
47	GLO1	GLO1 Entrez, Source	glyoxalase I	9022	-0.022	0.1330	No
48	UROD	UROD Entrez, Source	uroporphyrinogen decarboxylase	9864	-0.034	0.0771	No
49	ADCY8	ADCY8 Entrez, Source	adenylate cyclase 8 (brain)	10557	-0.046	0.0350	No
50	ALDOA	ALDOA Entrez, Source	aldolase A, fructose-bisphosphate	11945	-0.085	-0.0511	No
51	CA3	CA3 Entrez, Source	carbonic anhydrase III, muscle specific	13332	-0.725	0.0008	No