Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | MCALPAINPATHWAY |
| Enrichment Score (ES) | -0.69718766 |
| Normalized Enrichment Score (NES) | -1.8791387 |
| Nominal p-value | 0.0017825312 |
| FDR q-value | 0.025933808 |
| FWER p-Value | 0.743 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | EGF | EGF Entrez, Source | epidermal growth factor (beta-urogastrone) | 316 | 0.148 | 0.0272 | No |
| 2 | PRKAR2A | PRKAR2A Entrez, Source | protein kinase, cAMP-dependent, regulatory, type II, alpha | 1310 | 0.086 | -0.0179 | No |
| 3 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 2688 | 0.055 | -0.1022 | No |
| 4 | MYL2 | MYL2 Entrez, Source | myosin, light chain 2, regulatory, cardiac, slow | 2705 | 0.055 | -0.0844 | No |
| 5 | MAPK1 | MAPK1 Entrez, Source | mitogen-activated protein kinase 1 | 6633 | 0.006 | -0.3771 | No |
| 6 | ITGA1 | ITGA1 Entrez, Source | integrin, alpha 1 | 7816 | -0.007 | -0.4633 | No |
| 7 | PRKAR1A | PRKAR1A Entrez, Source | protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) | 7920 | -0.009 | -0.4681 | No |
| 8 | CXCR3 | CXCR3 Entrez, Source | chemokine (C-X-C motif) receptor 3 | 8942 | -0.021 | -0.5374 | No |
| 9 | HRAS | HRAS Entrez, Source | v-Ha-ras Harvey rat sarcoma viral oncogene homolog | 9267 | -0.025 | -0.5530 | No |
| 10 | ITGB1 | ITGB1 Entrez, Source | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 10521 | -0.046 | -0.6314 | No |
| 11 | TLN1 | TLN1 Entrez, Source | talin 1 | 10840 | -0.052 | -0.6372 | No |
| 12 | PTK2 | PTK2 Entrez, Source | PTK2 protein tyrosine kinase 2 | 10930 | -0.054 | -0.6251 | No |
| 13 | CAPN2 | CAPN2 Entrez, Source | calpain 2, (m/II) large subunit | 11891 | -0.083 | -0.6686 | Yes |
| 14 | CAPNS1 | CAPNS1 Entrez, Source | calpain, small subunit 1 | 12082 | -0.091 | -0.6516 | Yes |
| 15 | CAPN1 | CAPN1 Entrez, Source | calpain 1, (mu/I) large subunit | 12425 | -0.112 | -0.6386 | Yes |
| 16 | MAPK3 | MAPK3 Entrez, Source | mitogen-activated protein kinase 3 | 12674 | -0.132 | -0.6118 | Yes |
| 17 | PRKAR1B | PRKAR1B Entrez, Source | protein kinase, cAMP-dependent, regulatory, type I, beta | 12820 | -0.150 | -0.5710 | Yes |
| 18 | PXN | PXN Entrez, Source | paxillin | 12950 | -0.176 | -0.5202 | Yes |
| 19 | VIL2 | VIL2 Entrez, Source | villin 2 (ezrin) | 13025 | -0.196 | -0.4581 | Yes |
| 20 | PRKAR2B | PRKAR2B Entrez, Source | protein kinase, cAMP-dependent, regulatory, type II, beta | 13060 | -0.212 | -0.3876 | Yes |
| 21 | ACTA1 | ACTA1 Entrez, Source | actin, alpha 1, skeletal muscle | 13342 | -1.187 | -0.0000 | Yes |
