Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | MONOCARBOXYLIC_ACID_METABOLIC_PROCESS |
| Enrichment Score (ES) | 0.5720729 |
| Normalized Enrichment Score (NES) | 2.143707 |
| Nominal p-value | 0.0 |
| FDR q-value | 9.5178175E-4 |
| FWER p-Value | 0.022 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SLC27A5 | SLC27A5 Entrez, Source | solute carrier family 27 (fatty acid transporter), member 5 | 12 | 0.395 | 0.0722 | Yes |
| 2 | FTCD | FTCD Entrez, Source | formiminotransferase cyclodeaminase | 27 | 0.336 | 0.1333 | Yes |
| 3 | BBOX1 | BBOX1 Entrez, Source | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 37 | 0.303 | 0.1887 | Yes |
| 4 | SC4MOL | SC4MOL Entrez, Source | sterol-C4-methyl oxidase-like | 90 | 0.236 | 0.2285 | Yes |
| 5 | HACL1 | HACL1 Entrez, Source | 2-hydroxyacyl-CoA lyase 1 | 94 | 0.229 | 0.2706 | Yes |
| 6 | GLYAT | GLYAT Entrez, Source | glycine-N-acyltransferase | 102 | 0.225 | 0.3116 | Yes |
| 7 | PPARA | PPARA Entrez, Source | peroxisome proliferative activated receptor, alpha | 155 | 0.190 | 0.3429 | Yes |
| 8 | GCK | GCK Entrez, Source | glucokinase (hexokinase 4, maturity onset diabetes of the young 2) | 218 | 0.170 | 0.3696 | Yes |
| 9 | FADS2 | FADS2 Entrez, Source | fatty acid desaturase 2 | 362 | 0.140 | 0.3848 | Yes |
| 10 | NR1H4 | NR1H4 Entrez, Source | nuclear receptor subfamily 1, group H, member 4 | 390 | 0.137 | 0.4081 | Yes |
| 11 | ACOX2 | ACOX2 Entrez, Source | acyl-Coenzyme A oxidase 2, branched chain | 442 | 0.130 | 0.4284 | Yes |
| 12 | CPT1A | CPT1A Entrez, Source | carnitine palmitoyltransferase 1A (liver) | 469 | 0.128 | 0.4502 | Yes |
| 13 | PFKFB1 | PFKFB1 Entrez, Source | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 | 476 | 0.127 | 0.4733 | Yes |
| 14 | ALDH1L1 | ALDH1L1 Entrez, Source | aldehyde dehydrogenase 1 family, member L1 | 502 | 0.125 | 0.4945 | Yes |
| 15 | ACADVL | ACADVL Entrez, Source | acyl-Coenzyme A dehydrogenase, very long chain | 526 | 0.123 | 0.5155 | Yes |
| 16 | AGXT | AGXT Entrez, Source | alanine-glyoxylate aminotransferase (oxalosis I; hyperoxaluria I; glycolicaciduria; serine-pyruvate aminotransferase) | 591 | 0.118 | 0.5326 | Yes |
| 17 | SLC25A10 | SLC25A10 Entrez, Source | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 | 790 | 0.107 | 0.5376 | Yes |
| 18 | CD74 | CD74 Entrez, Source | CD74 molecule, major histocompatibility complex, class II invariant chain | 1097 | 0.093 | 0.5318 | Yes |
| 19 | ECHS1 | ECHS1 Entrez, Source | enoyl Coenzyme A hydratase, short chain, 1, mitochondrial | 1528 | 0.079 | 0.5140 | Yes |
| 20 | UGDH | UGDH Entrez, Source | UDP-glucose dehydrogenase | 1562 | 0.078 | 0.5259 | Yes |
| 21 | BAAT | BAAT Entrez, Source | bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase) | 1625 | 0.077 | 0.5354 | Yes |
| 22 | ACN9 | ACN9 Entrez, Source | ACN9 homolog (S. cerevisiae) | 1743 | 0.073 | 0.5402 | Yes |
| 23 | PTGES | PTGES Entrez, Source | prostaglandin E synthase | 1797 | 0.072 | 0.5495 | Yes |
| 24 | FADS1 | FADS1 Entrez, Source | fatty acid desaturase 1 | 1932 | 0.070 | 0.5523 | Yes |
| 25 | AKR1D1 | AKR1D1 Entrez, Source | aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase) | 2098 | 0.066 | 0.5521 | Yes |
| 26 | FAAH | FAAH Entrez, Source | fatty acid amide hydrolase | 2116 | 0.066 | 0.5629 | Yes |
| 27 | CYP4F2 | CYP4F2 Entrez, Source | cytochrome P450, family 4, subfamily F, polypeptide 2 | 2291 | 0.062 | 0.5614 | Yes |
| 28 | MLYCD | MLYCD Entrez, Source | malonyl-CoA decarboxylase | 2302 | 0.062 | 0.5721 | Yes |
| 29 | PPARD | PPARD Entrez, Source | peroxisome proliferative activated receptor, delta | 2558 | 0.058 | 0.5635 | No |
| 30 | TNFRSF1A | TNFRSF1A Entrez, Source | tumor necrosis factor receptor superfamily, member 1A | 2994 | 0.050 | 0.5400 | No |
| 31 | PTGS1 | PTGS1 Entrez, Source | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) | 3007 | 0.050 | 0.5484 | No |
| 32 | ACOT2 | ACOT2 Entrez, Source | acyl-CoA thioesterase 2 | 3435 | 0.044 | 0.5243 | No |
| 33 | ACADSB | ACADSB Entrez, Source | acyl-Coenzyme A dehydrogenase, short/branched chain | 3526 | 0.043 | 0.5254 | No |
| 34 | ATF4 | ATF4 Entrez, Source | activating transcription factor 4 (tax-responsive enhancer element B67) | 3579 | 0.042 | 0.5293 | No |
| 35 | GBA2 | GBA2 Entrez, Source | glucosidase, beta (bile acid) 2 | 3630 | 0.041 | 0.5332 | No |
| 36 | GNPAT | GNPAT Entrez, Source | glyceronephosphate O-acyltransferase | 3783 | 0.039 | 0.5290 | No |
| 37 | HPGD | HPGD Entrez, Source | hydroxyprostaglandin dehydrogenase 15-(NAD) | 3915 | 0.038 | 0.5261 | No |
| 38 | ALDH5A1 | ALDH5A1 Entrez, Source | aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase) | 4114 | 0.035 | 0.5177 | No |
| 39 | PECI | PECI Entrez, Source | peroxisomal D3,D2-enoyl-CoA isomerase | 4265 | 0.033 | 0.5125 | No |
| 40 | HADHB | HADHB Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit | 4313 | 0.032 | 0.5149 | No |
| 41 | IGF1 | IGF1 Entrez, Source | insulin-like growth factor 1 (somatomedin C) | 4345 | 0.032 | 0.5185 | No |
| 42 | ACOX3 | ACOX3 Entrez, Source | acyl-Coenzyme A oxidase 3, pristanoyl | 4732 | 0.027 | 0.4945 | No |
| 43 | HAO2 | HAO2 Entrez, Source | hydroxyacid oxidase 2 (long chain) | 4991 | 0.024 | 0.4795 | No |
| 44 | ACADM | ACADM Entrez, Source | acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain | 5845 | 0.014 | 0.4179 | No |
| 45 | PPARGC1A | PPARGC1A Entrez, Source | peroxisome proliferative activated receptor, gamma, coactivator 1, alpha | 6549 | 0.007 | 0.3663 | No |
| 46 | PTGDS | PTGDS Entrez, Source | prostaglandin D2 synthase 21kDa (brain) | 6985 | 0.002 | 0.3339 | No |
| 47 | ADIPOR2 | ADIPOR2 Entrez, Source | adiponectin receptor 2 | 7084 | 0.001 | 0.3268 | No |
| 48 | ACOT12 | ACOT12 Entrez, Source | acyl-CoA thioesterase 12 | 7714 | -0.006 | 0.2805 | No |
| 49 | ACADS | ACADS Entrez, Source | acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain | 7949 | -0.009 | 0.2645 | No |
| 50 | ECH1 | ECH1 Entrez, Source | enoyl Coenzyme A hydratase 1, peroxisomal | 8150 | -0.011 | 0.2515 | No |
| 51 | HSD3B7 | HSD3B7 Entrez, Source | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 | 8545 | -0.016 | 0.2248 | No |
| 52 | ARPP-19 | ARPP-19 Entrez, Source | - | 8985 | -0.022 | 0.1958 | No |
| 53 | CPT1B | CPT1B Entrez, Source | carnitine palmitoyltransferase 1B (muscle) | 9047 | -0.023 | 0.1954 | No |
| 54 | CYP7B1 | CYP7B1 Entrez, Source | cytochrome P450, family 7, subfamily B, polypeptide 1 | 9803 | -0.033 | 0.1447 | No |
| 55 | LTA4H | LTA4H Entrez, Source | leukotriene A4 hydrolase | 9958 | -0.036 | 0.1397 | No |
| 56 | ABCD2 | ABCD2 Entrez, Source | ATP-binding cassette, sub-family D (ALD), member 2 | 10245 | -0.041 | 0.1257 | No |
| 57 | ADIPOR1 | ADIPOR1 Entrez, Source | adiponectin receptor 1 | 10701 | -0.049 | 0.1006 | No |
| 58 | MIF | MIF Entrez, Source | macrophage migration inhibitory factor (glycosylation-inhibiting factor) | 11278 | -0.062 | 0.0686 | No |
| 59 | DEGS1 | DEGS1 Entrez, Source | degenerative spermatocyte homolog 1, lipid desaturase (Drosophila) | 11526 | -0.069 | 0.0628 | No |
| 60 | LYPLA3 | LYPLA3 Entrez, Source | lysophospholipase 3 (lysosomal phospholipase A2) | 12539 | -0.121 | 0.0089 | No |
| 61 | CROT | CROT Entrez, Source | carnitine O-octanoyltransferase | 12676 | -0.132 | 0.0231 | No |
| 62 | BRCA1 | BRCA1 Entrez, Source | breast cancer 1, early onset | 12787 | -0.146 | 0.0418 | No |
