Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | MONOVALENT_INORGANIC_CATION_TRANSPORT |
| Enrichment Score (ES) | 0.42150444 |
| Normalized Enrichment Score (NES) | 1.5917052 |
| Nominal p-value | 0.007614213 |
| FDR q-value | 0.097308405 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | KCNA2 | KCNA2 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 2 | 215 | 0.170 | 0.0379 | Yes |
| 2 | NOX1 | NOX1 Entrez, Source | NADPH oxidase 1 | 373 | 0.139 | 0.0703 | Yes |
| 3 | SCNN1A | SCNN1A Entrez, Source | sodium channel, nonvoltage-gated 1 alpha | 616 | 0.117 | 0.0894 | Yes |
| 4 | UCP1 | UCP1 Entrez, Source | uncoupling protein 1 (mitochondrial, proton carrier) | 627 | 0.117 | 0.1258 | Yes |
| 5 | KCNN3 | KCNN3 Entrez, Source | potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 | 884 | 0.103 | 0.1394 | Yes |
| 6 | SCN5A | SCN5A Entrez, Source | sodium channel, voltage-gated, type V, alpha (long QT syndrome 3) | 980 | 0.098 | 0.1636 | Yes |
| 7 | KCNJ10 | KCNJ10 Entrez, Source | potassium inwardly-rectifying channel, subfamily J, member 10 | 1373 | 0.083 | 0.1606 | Yes |
| 8 | KCNQ1 | KCNQ1 Entrez, Source | potassium voltage-gated channel, KQT-like subfamily, member 1 | 1472 | 0.080 | 0.1789 | Yes |
| 9 | SLC34A3 | SLC34A3 Entrez, Source | solute carrier family 34 (sodium phosphate), member 3 | 1497 | 0.079 | 0.2024 | Yes |
| 10 | KCNS1 | KCNS1 Entrez, Source | potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1 | 1635 | 0.076 | 0.2163 | Yes |
| 11 | KCNJ2 | KCNJ2 Entrez, Source | potassium inwardly-rectifying channel, subfamily J, member 2 | 1778 | 0.073 | 0.2287 | Yes |
| 12 | SCN4A | SCN4A Entrez, Source | sodium channel, voltage-gated, type IV, alpha | 1871 | 0.071 | 0.2443 | Yes |
| 13 | KCNH2 | KCNH2 Entrez, Source | potassium voltage-gated channel, subfamily H (eag-related), member 2 | 1971 | 0.069 | 0.2588 | Yes |
| 14 | SCN9A | SCN9A Entrez, Source | sodium channel, voltage-gated, type IX, alpha | 2059 | 0.067 | 0.2734 | Yes |
| 15 | KCNIP2 | KCNIP2 Entrez, Source | Kv channel interacting protein 2 | 2194 | 0.064 | 0.2838 | Yes |
| 16 | SCNN1G | SCNN1G Entrez, Source | sodium channel, nonvoltage-gated 1, gamma | 2288 | 0.062 | 0.2967 | Yes |
| 17 | KCNJ12 | KCNJ12 Entrez, Source | potassium inwardly-rectifying channel, subfamily J, member 12 | 2409 | 0.060 | 0.3068 | Yes |
| 18 | KCNJ4 | KCNJ4 Entrez, Source | potassium inwardly-rectifying channel, subfamily J, member 4 | 2467 | 0.059 | 0.3213 | Yes |
| 19 | KCNN1 | KCNN1 Entrez, Source | potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1 | 2496 | 0.059 | 0.3379 | Yes |
| 20 | KCNMB4 | KCNMB4 Entrez, Source | potassium large conductance calcium-activated channel, subfamily M, beta member 4 | 2759 | 0.054 | 0.3354 | Yes |
| 21 | KCNH1 | KCNH1 Entrez, Source | potassium voltage-gated channel, subfamily H (eag-related), member 1 | 2922 | 0.051 | 0.3395 | Yes |
| 22 | SCN7A | SCN7A Entrez, Source | sodium channel, voltage-gated, type VII, alpha | 3006 | 0.050 | 0.3492 | Yes |
| 23 | KCNAB1 | KCNAB1 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, beta member 1 | 3306 | 0.046 | 0.3412 | Yes |
| 24 | KCNH3 | KCNH3 Entrez, Source | potassium voltage-gated channel, subfamily H (eag-related), member 3 | 3309 | 0.046 | 0.3556 | Yes |
| 25 | KCNB2 | KCNB2 Entrez, Source | potassium voltage-gated channel, Shab-related subfamily, member 2 | 3321 | 0.045 | 0.3693 | Yes |
| 26 | KCNG2 | KCNG2 Entrez, Source | potassium voltage-gated channel, subfamily G, member 2 | 3538 | 0.042 | 0.3665 | Yes |
| 27 | KCNMB1 | KCNMB1 Entrez, Source | potassium large conductance calcium-activated channel, subfamily M, beta member 1 | 3598 | 0.042 | 0.3753 | Yes |
| 28 | KCNJ5 | KCNJ5 Entrez, Source | potassium inwardly-rectifying channel, subfamily J, member 5 | 3690 | 0.041 | 0.3814 | Yes |
| 29 | KCNJ11 | KCNJ11 Entrez, Source | potassium inwardly-rectifying channel, subfamily J, member 11 | 3807 | 0.039 | 0.3852 | Yes |
| 30 | KCNQ3 | KCNQ3 Entrez, Source | potassium voltage-gated channel, KQT-like subfamily, member 3 | 3973 | 0.037 | 0.3844 | Yes |
| 31 | SCN10A | SCN10A Entrez, Source | sodium channel, voltage-gated, type X, alpha | 4012 | 0.036 | 0.3931 | Yes |
| 32 | KCNS3 | KCNS3 Entrez, Source | potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3 | 4055 | 0.036 | 0.4013 | Yes |
| 33 | KCNJ15 | KCNJ15 Entrez, Source | potassium inwardly-rectifying channel, subfamily J, member 15 | 4296 | 0.033 | 0.3936 | Yes |
| 34 | SLC17A3 | SLC17A3 Entrez, Source | solute carrier family 17 (sodium phosphate), member 3 | 4338 | 0.032 | 0.4008 | Yes |
| 35 | KCNA6 | KCNA6 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 6 | 4340 | 0.032 | 0.4109 | Yes |
| 36 | KCNA5 | KCNA5 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 5 | 4364 | 0.032 | 0.4193 | Yes |
| 37 | ABCC9 | ABCC9 Entrez, Source | ATP-binding cassette, sub-family C (CFTR/MRP), member 9 | 4465 | 0.030 | 0.4215 | Yes |
| 38 | KCNV1 | KCNV1 Entrez, Source | potassium channel, subfamily V, member 1 | 4684 | 0.028 | 0.4139 | No |
| 39 | CHP | CHP Entrez, Source | - | 4702 | 0.028 | 0.4214 | No |
| 40 | KCNC3 | KCNC3 Entrez, Source | potassium voltage-gated channel, Shaw-related subfamily, member 3 | 5220 | 0.021 | 0.3892 | No |
| 41 | KCND3 | KCND3 Entrez, Source | potassium voltage-gated channel, Shal-related subfamily, member 3 | 5549 | 0.018 | 0.3702 | No |
| 42 | KCNK3 | KCNK3 Entrez, Source | potassium channel, subfamily K, member 3 | 5875 | 0.014 | 0.3502 | No |
| 43 | ATP1A4 | ATP1A4 Entrez, Source | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 5925 | 0.014 | 0.3508 | No |
| 44 | SCN4B | SCN4B Entrez, Source | sodium channel, voltage-gated, type IV, beta | 5970 | 0.013 | 0.3516 | No |
| 45 | KCNE2 | KCNE2 Entrez, Source | potassium voltage-gated channel, Isk-related family, member 2 | 6032 | 0.012 | 0.3510 | No |
| 46 | KCNJ1 | KCNJ1 Entrez, Source | potassium inwardly-rectifying channel, subfamily J, member 1 | 6556 | 0.007 | 0.3138 | No |
| 47 | KCNA3 | KCNA3 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 3 | 6733 | 0.005 | 0.3022 | No |
| 48 | UCP3 | UCP3 Entrez, Source | uncoupling protein 3 (mitochondrial, proton carrier) | 6915 | 0.003 | 0.2894 | No |
| 49 | KCNQ2 | KCNQ2 Entrez, Source | potassium voltage-gated channel, KQT-like subfamily, member 2 | 7163 | 0.000 | 0.2709 | No |
| 50 | KCNK1 | KCNK1 Entrez, Source | potassium channel, subfamily K, member 1 | 7451 | -0.003 | 0.2503 | No |
| 51 | ABCC8 | ABCC8 Entrez, Source | ATP-binding cassette, sub-family C (CFTR/MRP), member 8 | 7488 | -0.004 | 0.2487 | No |
| 52 | KCNE1 | KCNE1 Entrez, Source | potassium voltage-gated channel, Isk-related family, member 1 | 7817 | -0.007 | 0.2263 | No |
| 53 | SLC8A1 | SLC8A1 Entrez, Source | solute carrier family 8 (sodium/calcium exchanger), member 1 | 7943 | -0.009 | 0.2197 | No |
| 54 | SCN11A | SCN11A Entrez, Source | sodium channel, voltage-gated, type XI, alpha | 8007 | -0.010 | 0.2180 | No |
| 55 | KCNJ3 | KCNJ3 Entrez, Source | potassium inwardly-rectifying channel, subfamily J, member 3 | 8268 | -0.013 | 0.2024 | No |
| 56 | KCNH4 | KCNH4 Entrez, Source | potassium voltage-gated channel, subfamily H (eag-related), member 4 | 8439 | -0.015 | 0.1943 | No |
| 57 | KCNA4 | KCNA4 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 4 | 8735 | -0.018 | 0.1780 | No |
| 58 | KCNJ6 | KCNJ6 Entrez, Source | potassium inwardly-rectifying channel, subfamily J, member 6 | 9027 | -0.022 | 0.1631 | No |
| 59 | KCNN4 | KCNN4 Entrez, Source | potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 | 9045 | -0.023 | 0.1690 | No |
| 60 | ATP6AP1 | ATP6AP1 Entrez, Source | ATPase, H+ transporting, lysosomal accessory protein 1 | 9190 | -0.024 | 0.1659 | No |
| 61 | KCNAB3 | KCNAB3 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, beta member 3 | 9424 | -0.028 | 0.1573 | No |
| 62 | ATP6V1F | ATP6V1F Entrez, Source | ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F | 9426 | -0.028 | 0.1661 | No |
| 63 | ATP6V0C | ATP6V0C Entrez, Source | ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c | 9541 | -0.030 | 0.1669 | No |
| 64 | UCP2 | UCP2 Entrez, Source | uncoupling protein 2 (mitochondrial, proton carrier) | 9763 | -0.033 | 0.1607 | No |
| 65 | ATP6V0E1 | ATP6V0E1 Entrez, Source | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 | 9786 | -0.033 | 0.1697 | No |
| 66 | KCNA1 | KCNA1 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) | 10103 | -0.038 | 0.1581 | No |
| 67 | SCN1B | SCN1B Entrez, Source | sodium channel, voltage-gated, type I, beta | 10150 | -0.039 | 0.1672 | No |
| 68 | KCNC1 | KCNC1 Entrez, Source | potassium voltage-gated channel, Shaw-related subfamily, member 1 | 10154 | -0.039 | 0.1795 | No |
| 69 | ATP6V1E1 | ATP6V1E1 Entrez, Source | ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 | 10159 | -0.039 | 0.1917 | No |
| 70 | TCIRG1 | TCIRG1 Entrez, Source | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 | 10455 | -0.044 | 0.1836 | No |
| 71 | SCN2B | SCN2B Entrez, Source | sodium channel, voltage-gated, type II, beta | 10782 | -0.051 | 0.1754 | No |
| 72 | ATP6V1C1 | ATP6V1C1 Entrez, Source | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 | 10948 | -0.055 | 0.1804 | No |
