Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | MYOD_NIH3T3_UP |
| Enrichment Score (ES) | -0.538872 |
| Normalized Enrichment Score (NES) | -1.770313 |
| Nominal p-value | 0.0016666667 |
| FDR q-value | 0.0474981 |
| FWER p-Value | 0.994 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GADD45G | GADD45G Entrez, Source | growth arrest and DNA-damage-inducible, gamma | 160 | 0.189 | 0.0165 | No |
| 2 | HMGCS2 | HMGCS2 Entrez, Source | 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial) | 190 | 0.175 | 0.0407 | No |
| 3 | VKORC1 | VKORC1 Entrez, Source | vitamin K epoxide reductase complex, subunit 1 | 222 | 0.167 | 0.0636 | No |
| 4 | LRP4 | LRP4 Entrez, Source | low density lipoprotein receptor-related protein 4 | 331 | 0.145 | 0.0772 | No |
| 5 | TFRC | TFRC Entrez, Source | transferrin receptor (p90, CD71) | 439 | 0.131 | 0.0889 | No |
| 6 | MYOD1 | MYOD1 Entrez, Source | myogenic differentiation 1 | 868 | 0.104 | 0.0724 | No |
| 7 | PPFIA4 | PPFIA4 Entrez, Source | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 926 | 0.101 | 0.0834 | No |
| 8 | NAV2 | NAV2 Entrez, Source | neuron navigator 2 | 1171 | 0.090 | 0.0787 | No |
| 9 | RHOB | RHOB Entrez, Source | ras homolog gene family, member B | 1840 | 0.071 | 0.0391 | No |
| 10 | CHRNA1 | CHRNA1 Entrez, Source | cholinergic receptor, nicotinic, alpha 1 (muscle) | 2179 | 0.064 | 0.0234 | No |
| 11 | TNNT3 | TNNT3 Entrez, Source | troponin T type 3 (skeletal, fast) | 2298 | 0.062 | 0.0239 | No |
| 12 | MYH3 | MYH3 Entrez, Source | myosin, heavy chain 3, skeletal muscle, embryonic | 2301 | 0.062 | 0.0331 | No |
| 13 | IGFBP5 | IGFBP5 Entrez, Source | insulin-like growth factor binding protein 5 | 2629 | 0.056 | 0.0170 | No |
| 14 | TNNI2 | TNNI2 Entrez, Source | troponin I type 2 (skeletal, fast) | 2692 | 0.055 | 0.0207 | No |
| 15 | ATP2A1 | ATP2A1 Entrez, Source | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 | 2732 | 0.055 | 0.0260 | No |
| 16 | CHRNG | CHRNG Entrez, Source | cholinergic receptor, nicotinic, gamma | 3205 | 0.047 | -0.0024 | No |
| 17 | AKT2 | AKT2 Entrez, Source | v-akt murine thymoma viral oncogene homolog 2 | 4202 | 0.034 | -0.0723 | No |
| 18 | HES6 | HES6 Entrez, Source | hairy and enhancer of split 6 (Drosophila) | 4366 | 0.032 | -0.0798 | No |
| 19 | TNNT2 | TNNT2 Entrez, Source | troponin T type 2 (cardiac) | 5334 | 0.020 | -0.1495 | No |
| 20 | CKM | CKM Entrez, Source | creatine kinase, muscle | 5748 | 0.015 | -0.1783 | No |
| 21 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 5802 | 0.015 | -0.1800 | No |
| 22 | MYBPH | MYBPH Entrez, Source | myosin binding protein H | 5894 | 0.014 | -0.1848 | No |
| 23 | ENO3 | ENO3 Entrez, Source | enolase 3 (beta, muscle) | 6328 | 0.009 | -0.2159 | No |
| 24 | ATP1A1 | ATP1A1 Entrez, Source | ATPase, Na+/K+ transporting, alpha 1 polypeptide | 6356 | 0.009 | -0.2166 | No |
| 25 | STK17B | STK17B Entrez, Source | serine/threonine kinase 17b (apoptosis-inducing) | 6841 | 0.004 | -0.2525 | No |
| 26 | PDLIM3 | PDLIM3 Entrez, Source | PDZ and LIM domain 3 | 7252 | -0.001 | -0.2832 | No |
| 27 | HSPB8 | HSPB8 Entrez, Source | heat shock 22kDa protein 8 | 7306 | -0.001 | -0.2869 | No |
| 28 | GPC1 | GPC1 Entrez, Source | glypican 1 | 9818 | -0.034 | -0.4708 | No |
| 29 | PSMC3 | PSMC3 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 3 | 10034 | -0.037 | -0.4814 | No |
| 30 | MYOG | MYOG Entrez, Source | myogenin (myogenic factor 4) | 10152 | -0.039 | -0.4843 | No |
| 31 | KLHL5 | KLHL5 Entrez, Source | kelch-like 5 (Drosophila) | 10873 | -0.053 | -0.5304 | Yes |
| 32 | ANXA11 | ANXA11 Entrez, Source | annexin A11 | 10926 | -0.054 | -0.5262 | Yes |
| 33 | DCAKD | DCAKD Entrez, Source | dephospho-CoA kinase domain containing | 11096 | -0.058 | -0.5301 | Yes |
| 34 | CUGBP1 | CUGBP1 Entrez, Source | CUG triplet repeat, RNA binding protein 1 | 11120 | -0.058 | -0.5231 | Yes |
| 35 | HIP1 | HIP1 Entrez, Source | huntingtin interacting protein 1 | 11319 | -0.063 | -0.5285 | Yes |
| 36 | RB1 | RB1 Entrez, Source | retinoblastoma 1 (including osteosarcoma) | 11401 | -0.065 | -0.5248 | Yes |
| 37 | HRC | HRC Entrez, Source | histidine rich calcium binding protein | 11420 | -0.066 | -0.5162 | Yes |
| 38 | CCDC23 | CCDC23 Entrez, Source | coiled-coil domain containing 23 | 11490 | -0.068 | -0.5111 | Yes |
| 39 | CCND3 | CCND3 Entrez, Source | cyclin D3 | 11760 | -0.077 | -0.5197 | Yes |
| 40 | CD82 | CD82 Entrez, Source | CD82 molecule | 11868 | -0.082 | -0.5154 | Yes |
| 41 | PVR | PVR Entrez, Source | poliovirus receptor | 12103 | -0.092 | -0.5193 | Yes |
| 42 | HS2ST1 | HS2ST1 Entrez, Source | heparan sulfate 2-O-sulfotransferase 1 | 12339 | -0.107 | -0.5209 | Yes |
| 43 | BIN1 | BIN1 Entrez, Source | bridging integrator 1 | 12408 | -0.112 | -0.5091 | Yes |
| 44 | KLF5 | KLF5 Entrez, Source | Kruppel-like factor 5 (intestinal) | 12409 | -0.112 | -0.4923 | Yes |
| 45 | KIFC3 | KIFC3 Entrez, Source | kinesin family member C3 | 12529 | -0.120 | -0.4832 | Yes |
| 46 | PBXIP1 | PBXIP1 Entrez, Source | pre-B-cell leukemia transcription factor interacting protein 1 | 12745 | -0.140 | -0.4782 | Yes |
| 47 | PRKAR2B | PRKAR2B Entrez, Source | protein kinase, cAMP-dependent, regulatory, type II, beta | 13060 | -0.212 | -0.4699 | Yes |
| 48 | CHRNB1 | CHRNB1 Entrez, Source | cholinergic receptor, nicotinic, beta 1 (muscle) | 13070 | -0.218 | -0.4377 | Yes |
| 49 | PRND | PRND Entrez, Source | prion protein 2 (dublet) | 13159 | -0.264 | -0.4045 | Yes |
| 50 | RUNX1 | RUNX1 Entrez, Source | runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene) | 13180 | -0.281 | -0.3637 | Yes |
| 51 | SCHIP1 | SCHIP1 Entrez, Source | schwannomin interacting protein 1 | 13215 | -0.309 | -0.3196 | Yes |
| 52 | DBN1 | DBN1 Entrez, Source | drebrin 1 | 13305 | -0.475 | -0.2547 | Yes |
| 53 | PRSS23 | PRSS23 Entrez, Source | protease, serine, 23 | 13319 | -0.520 | -0.1773 | Yes |
| 54 | ACTA1 | ACTA1 Entrez, Source | actin, alpha 1, skeletal muscle | 13342 | -1.187 | 0.0000 | Yes |
