Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_48h_versus_single_gel_48h.class.cls
#double_gel_48h_versus_single_gel_48h_repos
Phenotypeclass.cls#double_gel_48h_versus_single_gel_48h_repos
Upregulated in classsingle_gel_48h
GeneSetNEGATIVE_REGULATION_OF_BIOLOGICAL_PROCESS
Enrichment Score (ES)-0.39067936
Normalized Enrichment Score (NES)-1.6814933
Nominal p-value0.0
FDR q-value0.075507306
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: NEGATIVE_REGULATION_OF_BIOLOGICAL_PROCESS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1MAFBMAFB
Entrez,  Source
v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)860.2400.0028No
2PLGPLG
Entrez,  Source
plasminogen1200.2060.0083No
3DHCR24DHCR24
Entrez,  Source
24-dehydrocholesterol reductase1670.1850.0120No
4FGFBP1FGFBP1
Entrez,  Source
fibroblast growth factor binding protein 12020.1720.0161No
5ANGPTL4ANGPTL4
Entrez,  Source
angiopoietin-like 42030.1720.0229No
6GCKGCK
Entrez,  Source
glucokinase (hexokinase 4, maturity onset diabetes of the young 2)2180.1700.0285No
7CD40LGCD40LG
Entrez,  Source
CD40 ligand (TNF superfamily, member 5, hyper-IgM syndrome)3170.1480.0267No
8TNNI3TNNI3
Entrez,  Source
troponin I type 3 (cardiac)4020.1350.0255No
9SFTPDSFTPD
Entrez,  Source
surfactant, pulmonary-associated protein D4470.1300.0272No
10OPRM1OPRM1
Entrez,  Source
opioid receptor, mu 14810.1270.0296No
11ID4ID4
Entrez,  Source
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein5470.1220.0294No
12APOA2APOA2
Entrez,  Source
apolipoprotein A-II6780.1130.0238No
13MDM4MDM4
Entrez,  Source
Mdm4, transformed 3T3 cell double minute 4, p53 binding protein (mouse)6830.1130.0279No
14IL4IL4
Entrez,  Source
interleukin 47410.1090.0278No
15THY1THY1
Entrez,  Source
Thy-1 cell surface antigen7480.1090.0316No
16SNCASNCA
Entrez,  Source
synuclein, alpha (non A4 component of amyloid precursor)8270.1060.0297No
17BRAFBRAF
Entrez,  Source
v-raf murine sarcoma viral oncogene homolog B18420.1050.0328No
18NR1I2NR1I2
Entrez,  Source
nuclear receptor subfamily 1, group I, member 28780.1040.0341No
19DLC1DLC1
Entrez,  Source
deleted in liver cancer 19600.0990.0318No
20CNTN4CNTN4
Entrez,  Source
contactin 49850.0980.0338No
21NF2NF2
Entrez,  Source
neurofibromin 2 (bilateral acoustic neuroma)10250.0960.0345No
22NR0B1NR0B1
Entrez,  Source
nuclear receptor subfamily 0, group B, member 110270.0960.0382No
23CD74CD74
Entrez,  Source
CD74 molecule, major histocompatibility complex, class II invariant chain10970.0930.0366No
24POU1F1POU1F1
Entrez,  Source
POU domain, class 1, transcription factor 1 (Pit1, growth hormone factor 1)11490.0910.0362No
25GAS7GAS7
Entrez,  Source
growth arrest-specific 711800.0900.0374No
26GCLCGCLC
Entrez,  Source
glutamate-cysteine ligase, catalytic subunit12370.0880.0366No
27PIM1PIM1
Entrez,  Source
pim-1 oncogene12640.0870.0380No
28IRF8IRF8
Entrez,  Source
interferon regulatory factor 814940.0800.0234No
29IL1BIL1B
Entrez,  Source
interleukin 1, beta14950.0790.0265No
30BCL2L10BCL2L10
Entrez,  Source
BCL2-like 10 (apoptosis facilitator)15930.0770.0221No
31CALCACALCA
Entrez,  Source
calcitonin/calcitonin-related polypeptide, alpha16100.0770.0239No
32PF4PF4
Entrez,  Source
platelet factor 4 (chemokine (C-X-C motif) ligand 4)16150.0770.0266No
33TWIST1TWIST1
Entrez,  Source
twist homolog 1 (acrocephalosyndactyly 3; Saethre-Chotzen syndrome) (Drosophila)16210.0770.0292No
34CENTD2CENTD2
Entrez,  Source
centaurin, delta 216610.0750.0291No
35BMP4BMP4
Entrez,  Source
bone morphogenetic protein 417270.0740.0270No
36NR0B2NR0B2
Entrez,  Source
nuclear receptor subfamily 0, group B, member 217320.0740.0296No
37NF1NF1
Entrez,  Source
neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease)18030.0720.0270No
38ELA2ELA2
Entrez,  Source
elastase 2, neutrophil18380.0710.0272No
39RHOBRHOB
Entrez,  Source
ras homolog gene family, member B18400.0710.0299No
40PROCPROC
Entrez,  Source
protein C (inactivator of coagulation factors Va and VIIIa)18810.0700.0296No
41MYCMYC
Entrez,  Source
v-myc myelocytomatosis viral oncogene homolog (avian)18960.0700.0312No
42PA2G4PA2G4
Entrez,  Source
proliferation-associated 2G4, 38kDa19580.0690.0292No
43RTKNRTKN
Entrez,  Source
rhotekin20710.0660.0232No
44TWIST2TWIST2
Entrez,  Source
twist homolog 2 (Drosophila)20940.0660.0241No
45FABP6FABP6
Entrez,  Source
fatty acid binding protein 6, ileal (gastrotropin)21000.0660.0263No
46GTPBP4GTPBP4
Entrez,  Source
GTP binding protein 421140.0660.0279No
47TOB1TOB1
Entrez,  Source
transducer of ERBB2, 121580.0650.0271No
48CGREF1CGREF1
Entrez,  Source
cell growth regulator with EF-hand domain 121840.0640.0277No
49GLRA1GLRA1
Entrez,  Source
glycine receptor, alpha 1 (startle disease/hyperekplexia, stiff man syndrome)23200.0620.0197No
50UHMK1UHMK1
Entrez,  Source
U2AF homology motif (UHM) kinase 123210.0620.0221No
51GRM8GRM8
Entrez,  Source
glutamate receptor, metabotropic 823490.0610.0224No
52SOCS3SOCS3
Entrez,  Source
suppressor of cytokine signaling 323550.0610.0244No
53TAOK3TAOK3
Entrez,  Source
TAO kinase 323720.0610.0255No
54IGFBP3IGFBP3
Entrez,  Source
insulin-like growth factor binding protein 324070.0600.0253No
55TNFRSF8TNFRSF8
Entrez,  Source
tumor necrosis factor receptor superfamily, member 824130.0600.0272No
56BTG1BTG1
Entrez,  Source
B-cell translocation gene 1, anti-proliferative24180.0600.0293No
57F2F2
Entrez,  Source
coagulation factor II (thrombin)24830.0590.0266No
58SIGIRRSIGIRR
Entrez,  Source
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain25260.0580.0257No
59RARRES1RARRES1
Entrez,  Source
retinoic acid receptor responder (tazarotene induced) 125390.0580.0270No
60PPARDPPARD
Entrez,  Source
peroxisome proliferative activated receptor, delta25580.0580.0279No
61NDNNDN
Entrez,  Source
necdin homolog (mouse)25730.0570.0291No
62LIFLIF
Entrez,  Source
leukemia inhibitory factor (cholinergic differentiation factor)26600.0560.0246No
63NKX2-5NKX2-5
Entrez,  Source
NK2 transcription factor related, locus 5 (Drosophila)27860.0540.0171No
64SSTR4SSTR4
Entrez,  Source
somatostatin receptor 428380.0530.0152No
65IL11IL11
Entrez,  Source
interleukin 1129260.0510.0105No
66IL3IL3
Entrez,  Source
interleukin 3 (colony-stimulating factor, multiple)29350.0510.0119No
67CIAPIN1CIAPIN1
Entrez,  Source
cytokine induced apoptosis inhibitor 129740.0500.0109No
68NPR1NPR1
Entrez,  Source
natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)29760.0500.0128No
69APOA1APOA1
Entrez,  Source
apolipoprotein A-I30810.0490.0067No
70NUAK2NUAK2
Entrez,  Source
NUAK family, SNF1-like kinase, 231420.0480.0040No
71GNRH1GNRH1
Entrez,  Source
gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)31670.0480.0040No
72HIPK3HIPK3
Entrez,  Source
homeodomain interacting protein kinase 332170.0470.0021No
73FOXD3FOXD3
Entrez,  Source
forkhead box D332430.0470.0020No
74TBRG4TBRG4
Entrez,  Source
transforming growth factor beta regulator 434280.044-0.0105No
75WWP1WWP1
Entrez,  Source
WW domain containing E3 ubiquitin protein ligase 134590.044-0.0111No
76CD164CD164
Entrez,  Source
CD164 molecule, sialomucin35160.043-0.0138No
77RUNX3RUNX3
Entrez,  Source
runt-related transcription factor 335870.042-0.0175No
78NOTCH2NOTCH2
Entrez,  Source
Notch homolog 2 (Drosophila)36520.041-0.0209No
79AIF1AIF1
Entrez,  Source
allograft inflammatory factor 136790.041-0.0213No
80NOTCH4NOTCH4
Entrez,  Source
Notch homolog 4 (Drosophila)36940.041-0.0208No
81CRYAACRYAA
Entrez,  Source
crystallin, alpha A37400.040-0.0227No
82MYST3MYST3
Entrez,  Source
MYST histone acetyltransferase (monocytic leukemia) 337480.040-0.0216No
83RFX3RFX3
Entrez,  Source
regulatory factor X, 3 (influences HLA class II expression)37570.040-0.0207No
84CUL5CUL5
Entrez,  Source
cullin 538680.038-0.0277No
85CSDACSDA
Entrez,  Source
cold shock domain protein A38800.038-0.0270No
86HPGDHPGD
Entrez,  Source
hydroxyprostaglandin dehydrogenase 15-(NAD)39150.038-0.0282No
87BTG2BTG2
Entrez,  Source
BTG family, member 239270.037-0.0275No
88TBX3TBX3
Entrez,  Source
T-box 3 (ulnar mammary syndrome)41510.034-0.0434No
89EREGEREG
Entrez,  Source
epiregulin41570.034-0.0424No
90OSGIN1OSGIN1
Entrez,  Source
oxidative stress induced growth inhibitor 141800.034-0.0428No
91IL2RBIL2RB
Entrez,  Source
interleukin 2 receptor, beta41910.034-0.0423No
92INHAINHA
Entrez,  Source
inhibin, alpha42040.034-0.0419No
93GHSRGHSR
Entrez,  Source
growth hormone secretagogue receptor42260.033-0.0422No
94PTHLHPTHLH
Entrez,  Source
parathyroid hormone-like hormone42630.033-0.0437No
95AATFAATF
Entrez,  Source
apoptosis antagonizing transcription factor42950.033-0.0448No
96CDKN3CDKN3
Entrez,  Source
cyclin-dependent kinase inhibitor 3 (CDK2-associated dual specificity phosphatase)43030.033-0.0440No
97BCL2BCL2
Entrez,  Source
B-cell CLL/lymphoma 243280.032-0.0446No
98CBLCCBLC
Entrez,  Source
Cas-Br-M (murine) ecotropic retroviral transforming sequence c43410.032-0.0443No
99NFKBIL1NFKBIL1
Entrez,  Source
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 144000.031-0.0475No
100CHRNA7CHRNA7
Entrez,  Source
cholinergic receptor, nicotinic, alpha 745700.029-0.0594No
101PTENPTEN
Entrez,  Source
phosphatase and tensin homolog (mutated in multiple advanced cancers 1)45720.029-0.0584No
102BCL2A1BCL2A1
Entrez,  Source
BCL2-related protein A146100.029-0.0601No
103TBX5TBX5
Entrez,  Source
T-box 546820.028-0.0645No
104RUNX2RUNX2
Entrez,  Source
runt-related transcription factor 247040.027-0.0650No
105AMBPAMBP
Entrez,  Source
alpha-1-microglobulin/bikunin precursor47250.027-0.0655No
106EIF4G2EIF4G2
Entrez,  Source
eukaryotic translation initiation factor 4 gamma, 247290.027-0.0647No
107IGF1RIGF1R
Entrez,  Source
insulin-like growth factor 1 receptor47430.027-0.0646No
108ILF3ILF3
Entrez,  Source
interleukin enhancer binding factor 3, 90kDa47790.027-0.0663No
109RAD17RAD17
Entrez,  Source
RAD17 homolog (S. pombe)48150.026-0.0680No
110FASFAS
Entrez,  Source
Fas (TNF receptor superfamily, member 6)48360.026-0.0685No
111SCINSCIN
Entrez,  Source
scinderin48410.026-0.0678No
112PROK2PROK2
Entrez,  Source
prokineticin 248830.025-0.0700No
113LST1LST1
Entrez,  Source
leukocyte specific transcript 149070.025-0.0708No
114NPM1NPM1
Entrez,  Source
nucleophosmin (nucleolar phosphoprotein B23, numatrin)49790.024-0.0753No
115PEX14PEX14
Entrez,  Source
peroxisomal biogenesis factor 1450190.024-0.0774No
116CDKN1CCDKN1C
Entrez,  Source
cyclin-dependent kinase inhibitor 1C (p57, Kip2)50200.024-0.0764No
117BMP7BMP7
Entrez,  Source
bone morphogenetic protein 7 (osteogenic protein 1)51070.023-0.0822No
118ADRB3ADRB3
Entrez,  Source
adrenergic, beta-3-, receptor51280.022-0.0829No
119SUMO1SUMO1
Entrez,  Source
SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)51420.022-0.0830No
120BNIP1BNIP1
Entrez,  Source
BCL2/adenovirus E1B 19kDa interacting protein 151500.022-0.0827No
121GADD45AGADD45A
Entrez,  Source
growth arrest and DNA-damage-inducible, alpha51780.022-0.0839No
122CDK5RAP1CDK5RAP1
Entrez,  Source
CDK5 regulatory subunit associated protein 152040.021-0.0850No
123TGFB2TGFB2
Entrez,  Source
transforming growth factor, beta 253530.020-0.0956No
124SERPINF1SERPINF1
Entrez,  Source
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 153980.019-0.0983No
125NME1NME1
Entrez,  Source
non-metastatic cells 1, protein (NM23A) expressed in54030.019-0.0978No
126MECP2MECP2
Entrez,  Source
methyl CpG binding protein 2 (Rett syndrome)54440.019-0.1002No
127SONSON
Entrez,  Source
SON DNA binding protein54460.019-0.0995No
128ZFP161ZFP161
Entrez,  Source
zinc finger protein 161 homolog (mouse)55130.018-0.1039No
129IHPK2IHPK2
Entrez,  Source
inositol hexaphosphate kinase 255290.018-0.1044No
130SHHSHH
Entrez,  Source
sonic hedgehog homolog (Drosophila)55470.018-0.1050No
131ATXN1ATXN1
Entrez,  Source
ataxin 155520.018-0.1046No
132CTCFCTCF
Entrez,  Source
CCCTC-binding factor (zinc finger protein)56450.017-0.1110No
133SPNSPN
Entrez,  Source
sialophorin (leukosialin, CD43)57310.016-0.1170No
134CDKN1ACDKN1A
Entrez,  Source
cyclin-dependent kinase inhibitor 1A (p21, Cip1)58020.015-0.1218No
135MID1IP1MID1IP1
Entrez,  Source
MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish))58420.014-0.1242No
136TNP1TNP1
Entrez,  Source
transition protein 1 (during histone to protamine replacement)58430.014-0.1237No
137PPM1GPPM1G
Entrez,  Source
protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform58800.014-0.1259No
138PER1PER1
Entrez,  Source
period homolog 1 (Drosophila)59440.013-0.1302No
139ACVR1ACVR1
Entrez,  Source
activin A receptor, type I59550.013-0.1305No
140ZHX3ZHX3
Entrez,  Source
zinc fingers and homeoboxes 359850.013-0.1322No
141ORC2LORC2L
Entrez,  Source
origin recognition complex, subunit 2-like (yeast)60170.013-0.1341No
142ARHGDIBARHGDIB
Entrez,  Source
Rho GDP dissociation inhibitor (GDI) beta60800.012-0.1384No
143NME2NME2
Entrez,  Source
non-metastatic cells 2, protein (NM23B) expressed in61080.012-0.1400No
144CLN3CLN3
Entrez,  Source
ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)61390.012-0.1419No
145CDK10CDK10
Entrez,  Source
cyclin-dependent kinase (CDC2-like) 1061680.011-0.1436No
146KLF10KLF10
Entrez,  Source
Kruppel-like factor 1061860.011-0.1445No
147HMGB1HMGB1
Entrez,  Source
high-mobility group box 162190.011-0.1465No
148PRKCZPRKCZ
Entrez,  Source
protein kinase C, zeta62200.011-0.1461No
149FTH1FTH1
Entrez,  Source
ferritin, heavy polypeptide 162270.011-0.1462No
150TPT1TPT1
Entrez,  Source
tumor protein, translationally-controlled 162760.010-0.1495No
151ATPIF1ATPIF1
Entrez,  Source
ATPase inhibitory factor 163650.009-0.1559No
152SOCS2SOCS2
Entrez,  Source
suppressor of cytokine signaling 264000.009-0.1582No
153MAP2K6MAP2K6
Entrez,  Source
mitogen-activated protein kinase kinase 664810.008-0.1641No
154AHSGAHSG
Entrez,  Source
alpha-2-HS-glycoprotein66520.006-0.1770No
155ZNF148ZNF148
Entrez,  Source
zinc finger protein 14867510.005-0.1843No
156TNFTNF
Entrez,  Source
tumor necrosis factor (TNF superfamily, member 2)67780.004-0.1862No
157IL6IL6
Entrez,  Source
interleukin 6 (interferon, beta 2)68640.004-0.1926No
158ALBALB
Entrez,  Source
albumin68880.003-0.1942No
159ARF6ARF6
Entrez,  Source
ADP-ribosylation factor 668990.003-0.1949No
160TAX1BP1TAX1BP1
Entrez,  Source
Tax1 (human T-cell leukemia virus type I) binding protein 169830.002-0.2012No
161GATAD2AGATAD2A
Entrez,  Source
GATA zinc finger domain containing 2A69880.002-0.2015No
162PHBPHB
Entrez,  Source
prohibitin70280.002-0.2044No
163APCAPC
Entrez,  Source
adenomatosis polyposis coli70290.002-0.2043No
164TGFB1TGFB1
Entrez,  Source
transforming growth factor, beta 1 (Camurati-Engelmann disease)70530.001-0.2061No
165IL1AIL1A
Entrez,  Source
interleukin 1, alpha70650.001-0.2069No
166FRZBFRZB
Entrez,  Source
frizzled-related protein70850.001-0.2083No
167IL10IL10
Entrez,  Source
interleukin 1070910.001-0.2086No
168TGFB1I1TGFB1I1
Entrez,  Source
transforming growth factor beta 1 induced transcript 171210.001-0.2108No
169CDKN2CCDKN2C
Entrez,  Source
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)71600.000-0.2138No
170BCL2L2BCL2L2
Entrez,  Source
BCL2-like 27256-0.001-0.2210No
171CGRRF1CGRRF1
Entrez,  Source
cell growth regulator with ring finger domain 17267-0.001-0.2218No
172SSTR2SSTR2
Entrez,  Source
somatostatin receptor 27284-0.001-0.2230No
173ACVRL1ACVRL1
Entrez,  Source
activin A receptor type II-like 17285-0.001-0.2229No
174CARTPTCARTPT
Entrez,  Source
CART prepropeptide7384-0.002-0.2304No
175SSTR5SSTR5
Entrez,  Source
somatostatin receptor 57425-0.003-0.2334No
176ZBTB17ZBTB17
Entrez,  Source
zinc finger and BTB domain containing 177437-0.003-0.2341No
177BECN1BECN1
Entrez,  Source
beclin 1 (coiled-coil, myosin-like BCL2 interacting protein)7449-0.003-0.2348No
178NOX4NOX4
Entrez,  Source
NADPH oxidase 47556-0.004-0.2428No
179PTCH1PTCH1
Entrez,  Source
patched homolog 1 (Drosophila)7559-0.004-0.2428No
180HSPB1HSPB1
Entrez,  Source
heat shock 27kDa protein 17586-0.005-0.2446No
181ASNSASNS
Entrez,  Source
asparagine synthetase7614-0.005-0.2465No
182RASA1RASA1
Entrez,  Source
RAS p21 protein activator (GTPase activating protein) 17619-0.005-0.2466No
183ZBTB16ZBTB16
Entrez,  Source
zinc finger and BTB domain containing 167635-0.005-0.2476No
184INHBAINHBA
Entrez,  Source
inhibin, beta A (activin A, activin AB alpha polypeptide)7648-0.005-0.2483No
185EMP3EMP3
Entrez,  Source
epithelial membrane protein 37711-0.006-0.2529No
186FUSIP1FUSIP1
Entrez,  Source
FUS interacting protein (serine/arginine-rich) 17804-0.007-0.2597No
187SFRP1SFRP1
Entrez,  Source
secreted frizzled-related protein 17830-0.007-0.2613No
188APBB1APBB1
Entrez,  Source
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)7884-0.008-0.2651No
189PPP1R9BPPP1R9B
Entrez,  Source
protein phosphatase 1, regulatory subunit 9B, spinophilin7947-0.009-0.2695No
190WARSWARS
Entrez,  Source
tryptophanyl-tRNA synthetase7995-0.009-0.2728No
191OPA1OPA1
Entrez,  Source
optic atrophy 1 (autosomal dominant)8024-0.010-0.2745No
192CXCL1CXCL1
Entrez,  Source
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)8149-0.011-0.2837No
193RHOHRHOH
Entrez,  Source
ras homolog gene family, member H8155-0.011-0.2836No
194ARHGDIAARHGDIA
Entrez,  Source
Rho GDP dissociation inhibitor (GDI) alpha8158-0.011-0.2833No
195SPEGSPEG
Entrez,  Source
SPEG complex locus8241-0.012-0.2892No
196DLG1DLG1
Entrez,  Source
discs, large homolog 1 (Drosophila)8290-0.013-0.2924No
197IL2IL2
Entrez,  Source
interleukin 28295-0.013-0.2922No
198ZHX1ZHX1
Entrez,  Source
zinc fingers and homeoboxes 18296-0.013-0.2917No
199NFX1NFX1
Entrez,  Source
nuclear transcription factor, X-box binding 18306-0.013-0.2919No
200BARD1BARD1
Entrez,  Source
BRCA1 associated RING domain 18325-0.013-0.2927No
201IL17FIL17F
Entrez,  Source
interleukin 17F8354-0.014-0.2943No
202BCL10BCL10
Entrez,  Source
B-cell CLL/lymphoma 108361-0.014-0.2943No
203FAF1FAF1
Entrez,  Source
Fas (TNFRSF6) associated factor 18442-0.015-0.2999No
204CFLARCFLAR
Entrez,  Source
CASP8 and FADD-like apoptosis regulator8465-0.015-0.3010No
205GDNFGDNF
Entrez,  Source
glial cell derived neurotrophic factor8466-0.015-0.3004No
206B4GALT7B4GALT7
Entrez,  Source
xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I)8468-0.015-0.2999No
207SSTSST
Entrez,  Source
somatostatin8488-0.015-0.3007No
208GAS8GAS8
Entrez,  Source
growth arrest-specific 88547-0.016-0.3046No
209ARHGEF2ARHGEF2
Entrez,  Source
rho/rac guanine nucleotide exchange factor (GEF) 28556-0.016-0.3045No
210MEN1MEN1
Entrez,  Source
multiple endocrine neoplasia I8600-0.017-0.3072No
211CDK6CDK6
Entrez,  Source
cyclin-dependent kinase 68604-0.017-0.3068No
212UMODUMOD
Entrez,  Source
uromodulin (uromucoid, Tamm-Horsfall glycoprotein)8649-0.017-0.3095No
213BNIP3BNIP3
Entrez,  Source
BCL2/adenovirus E1B 19kDa interacting protein 38690-0.018-0.3119No
214DAXXDAXX
Entrez,  Source
death-associated protein 68710-0.018-0.3126No
215SCYE1SCYE1
Entrez,  Source
small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating)8723-0.018-0.3128No
216DNMT1DNMT1
Entrez,  Source
DNA (cytosine-5-)-methyltransferase 18763-0.019-0.3151No
217DAD1DAD1
Entrez,  Source
defender against cell death 18855-0.020-0.3214No
218BBC3BBC3
Entrez,  Source
BCL2 binding component 38982-0.022-0.3302No
219TSC1TSC1
Entrez,  Source
tuberous sclerosis 18983-0.022-0.3294No
220ARID5AARID5A
Entrez,  Source
AT rich interactive domain 5A (MRF1-like)8990-0.022-0.3290No
221CNOT8CNOT8
Entrez,  Source
CCR4-NOT transcription complex, subunit 89002-0.022-0.3290No
222SUPT5HSUPT5H
Entrez,  Source
suppressor of Ty 5 homolog (S. cerevisiae)9020-0.022-0.3294No
223GLO1GLO1
Entrez,  Source
glyoxalase I9022-0.022-0.3286No
224DEDDDEDD
Entrez,  Source
death effector domain containing9042-0.022-0.3292No
225VDRVDR
Entrez,  Source
vitamin D (1,25- dihydroxyvitamin D3) receptor9079-0.023-0.3311No
226MFN2MFN2
Entrez,  Source
mitofusin 29083-0.023-0.3304No
227MCL1MCL1
Entrez,  Source
myeloid cell leukemia sequence 1 (BCL2-related)9085-0.023-0.3296No
228SOD1SOD1
Entrez,  Source
superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult))9099-0.023-0.3297No
229POU2F1POU2F1
Entrez,  Source
POU domain, class 2, transcription factor 19137-0.024-0.3316No
230BTG4BTG4
Entrez,  Source
B-cell translocation gene 49236-0.025-0.3382No
231PRDX2PRDX2
Entrez,  Source
peroxiredoxin 29329-0.026-0.3443No
232ADRA1AADRA1A
Entrez,  Source
adrenergic, alpha-1A-, receptor9363-0.027-0.3458No
233ID2ID2
Entrez,  Source
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein9384-0.027-0.3463No
234PIAS4PIAS4
Entrez,  Source
protein inhibitor of activated STAT, 49415-0.028-0.3475No
235STAT3STAT3
Entrez,  Source
signal transducer and activator of transcription 3 (acute-phase response factor)9416-0.028-0.3464No
236SSTR1SSTR1
Entrez,  Source
somatostatin receptor 19531-0.029-0.3540No
237PHF12PHF12
Entrez,  Source
PHD finger protein 129599-0.030-0.3580No
238TP53TP53
Entrez,  Source
tumor protein p53 (Li-Fraumeni syndrome)9613-0.031-0.3578No
239PCAFPCAF
Entrez,  Source
p300/CBP-associated factor9640-0.031-0.3586No
240ID1ID1
Entrez,  Source
inhibitor of DNA binding 1, dominant negative helix-loop-helix protein9654-0.031-0.3584No
241COMMD7COMMD7
Entrez,  Source
COMM domain containing 79666-0.032-0.3580No
242SOSTSOST
Entrez,  Source
sclerosteosis9770-0.033-0.3646No
243NBNNBN
Entrez,  Source
nibrin9779-0.033-0.3640No
244CLIC4CLIC4
Entrez,  Source
chloride intracellular channel 49801-0.033-0.3643No
245ING4ING4
Entrez,  Source
inhibitor of growth family, member 49821-0.034-0.3644No
246BRCA2BRCA2
Entrez,  Source
breast cancer 2, early onset9823-0.034-0.3632No
247RASSF1RASSF1
Entrez,  Source
Ras association (RalGDS/AF-6) domain family 19841-0.034-0.3631No
248HDAC3HDAC3
Entrez,  Source
histone deacetylase 39948-0.036-0.3699No
249SH3GLB1SH3GLB1
Entrez,  Source
SH3-domain GRB2-like endophilin B19998-0.037-0.3723No
250SOCS1SOCS1
Entrez,  Source
suppressor of cytokine signaling 110039-0.037-0.3739No
251TERF2IPTERF2IP
Entrez,  Source
telomeric repeat binding factor 2, interacting protein10083-0.038-0.3757No
252CAPGCAPG
Entrez,  Source
capping protein (actin filament), gelsolin-like10094-0.038-0.3750No
253SPHK1SPHK1
Entrez,  Source
sphingosine kinase 110209-0.040-0.3822No
254BAXBAX
Entrez,  Source
BCL2-associated X protein10281-0.041-0.3861No
255BACE2BACE2
Entrez,  Source
beta-site APP-cleaving enzyme 210308-0.042-0.3865No
256ING1ING1
Entrez,  Source
inhibitor of growth family, member 110309-0.042-0.3848No
257YWHAZYWHAZ
Entrez,  Source
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide10313-0.042-0.3834No
258DFFADFFA
Entrez,  Source
DNA fragmentation factor, 45kDa, alpha polypeptide10349-0.042-0.3845No
259HGSHGS
Entrez,  Source
hepatocyte growth factor-regulated tyrosine kinase substrate10366-0.043-0.3840No
260SIRT5SIRT5
Entrez,  Source
sirtuin (silent mating type information regulation 2 homolog) 5 (S. cerevisiae)10370-0.043-0.3826No
261ZNF24ZNF24
Entrez,  Source
zinc finger protein 2410380-0.043-0.3816No
262GHRLGHRL
Entrez,  Source
ghrelin/obestatin preprohormone10393-0.043-0.3808No
263MAPK12MAPK12
Entrez,  Source
mitogen-activated protein kinase 1210400-0.044-0.3796No
264IER3IER3
Entrez,  Source
immediate early response 310439-0.044-0.3808No
265SMAD4SMAD4
Entrez,  Source
SMAD, mothers against DPP homolog 4 (Drosophila)10473-0.045-0.3816No
266KATNB1KATNB1
Entrez,  Source
katanin p80 (WD repeat containing) subunit B 110476-0.045-0.3800No
267PSEN1PSEN1
Entrez,  Source
presenilin 1 (Alzheimer disease 3)10571-0.046-0.3854No
268DR1DR1
Entrez,  Source
down-regulator of transcription 1, TBP-binding (negative cofactor 2)10633-0.048-0.3882No
269BCL2L1BCL2L1
Entrez,  Source
BCL2-like 110657-0.048-0.3881No
270BAG4BAG4
Entrez,  Source
BCL2-associated athanogene 410691-0.049-0.3888Yes
271CDC42CDC42
Entrez,  Source
cell division cycle 42 (GTP binding protein, 25kDa)10703-0.049-0.3877Yes
272GPX1GPX1
Entrez,  Source
glutathione peroxidase 110706-0.050-0.3859Yes
273CD28CD28
Entrez,  Source
CD28 molecule10719-0.050-0.3849Yes
274TOB2TOB2
Entrez,  Source
transducer of ERBB2, 210720-0.050-0.3829Yes
275TBRG1TBRG1
Entrez,  Source
transforming growth factor beta regulator 110757-0.051-0.3837Yes
276PIK3R2PIK3R2
Entrez,  Source
phosphoinositide-3-kinase, regulatory subunit 2 (p85 beta)10802-0.052-0.3851Yes
277COL18A1COL18A1
Entrez,  Source
collagen, type XVIII, alpha 110828-0.052-0.3849Yes
278MXI1MXI1
Entrez,  Source
MAX interactor 110848-0.053-0.3844Yes
279BCLAF1BCLAF1
Entrez,  Source
BCL2-associated transcription factor 110849-0.053-0.3823Yes
280GLMNGLMN
Entrez,  Source
glomulin, FKBP associated protein10862-0.053-0.3811Yes
281SERPINB2SERPINB2
Entrez,  Source
serpin peptidase inhibitor, clade B (ovalbumin), member 210863-0.053-0.3791Yes
282TGFBITGFBI
Entrez,  Source
transforming growth factor, beta-induced, 68kDa10868-0.053-0.3773Yes
283SERTAD2SERTAD2
Entrez,  Source
SERTA domain containing 210912-0.054-0.3785Yes
284RAC1RAC1
Entrez,  Source
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)10939-0.055-0.3784Yes
285ADAMTS1ADAMTS1
Entrez,  Source
ADAM metallopeptidase with thrombospondin type 1 motif, 110942-0.055-0.3764Yes
286PACSIN3PACSIN3
Entrez,  Source
protein kinase C and casein kinase substrate in neurons 310954-0.055-0.3751Yes
287YWHAHYWHAH
Entrez,  Source
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide11003-0.056-0.3766Yes
288CDKN2BCDKN2B
Entrez,  Source
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)11022-0.056-0.3758Yes
289PCGF6PCGF6
Entrez,  Source
polycomb group ring finger 611033-0.057-0.3743Yes
290BFARBFAR
Entrez,  Source
bifunctional apoptosis regulator11056-0.057-0.3738Yes
291HSBP1HSBP1
Entrez,  Source
heat shock factor binding protein 111060-0.057-0.3718Yes
292ZMYND11ZMYND11
Entrez,  Source
zinc finger, MYND domain containing 1111091-0.058-0.3718Yes
293BTG3BTG3
Entrez,  Source
BTG family, member 311098-0.058-0.3700Yes
294TXNDC1TXNDC1
Entrez,  Source
thioredoxin domain containing 111099-0.058-0.3677Yes
295SMAD3SMAD3
Entrez,  Source
SMAD, mothers against DPP homolog 3 (Drosophila)11131-0.059-0.3678Yes
296RELARELA
Entrez,  Source
v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian)11138-0.059-0.3660Yes
297ADAM10ADAM10
Entrez,  Source
ADAM metallopeptidase domain 1011154-0.059-0.3648Yes
298NUP62NUP62
Entrez,  Source
nucleoporin 62kDa11191-0.060-0.3652Yes
299ADRB2ADRB2
Entrez,  Source
adrenergic, beta-2-, receptor, surface11210-0.060-0.3642Yes
300SMAD2SMAD2
Entrez,  Source
SMAD, mothers against DPP homolog 2 (Drosophila)11223-0.061-0.3628Yes
301EIF2AK2EIF2AK2
Entrez,  Source
eukaryotic translation initiation factor 2-alpha kinase 211242-0.061-0.3618Yes
302PLAGL1PLAGL1
Entrez,  Source
pleiomorphic adenoma gene-like 111247-0.061-0.3597Yes
303BIRC5BIRC5
Entrez,  Source
baculoviral IAP repeat-containing 5 (survivin)11253-0.061-0.3577Yes
304BIRC4BIRC4
Entrez,  Source
baculoviral IAP repeat-containing 411256-0.061-0.3554Yes
305MIFMIF
Entrez,  Source
macrophage migration inhibitory factor (glycosylation-inhibiting factor)11278-0.062-0.3546Yes
306TARBP2TARBP2
Entrez,  Source
Tar (HIV-1) RNA binding protein 211281-0.062-0.3524Yes
307SCG2SCG2
Entrez,  Source
secretogranin II (chromogranin C)11333-0.063-0.3538Yes
308CTBP1CTBP1
Entrez,  Source
C-terminal binding protein 111368-0.064-0.3539Yes
309RND1RND1
Entrez,  Source
Rho family GTPase 111382-0.065-0.3524Yes
310RB1RB1
Entrez,  Source
retinoblastoma 1 (including osteosarcoma)11401-0.065-0.3512Yes
311IGFBP6IGFBP6
Entrez,  Source
insulin-like growth factor binding protein 611430-0.066-0.3508Yes
312EIF2AK3EIF2AK3
Entrez,  Source
eukaryotic translation initiation factor 2-alpha kinase 311434-0.066-0.3484Yes
313NOTCH1NOTCH1
Entrez,  Source
Notch homolog 1, translocation-associated (Drosophila)11455-0.067-0.3474Yes
314LEPLEP
Entrez,  Source
leptin (obesity homolog, mouse)11480-0.068-0.3466Yes
315NPPBNPPB
Entrez,  Source
natriuretic peptide precursor B11482-0.068-0.3440Yes
316NFKB1NFKB1
Entrez,  Source
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105)11510-0.069-0.3434Yes
317IRF7IRF7
Entrez,  Source
interferon regulatory factor 711527-0.069-0.3419Yes
318KLF4KLF4
Entrez,  Source
Kruppel-like factor 4 (gut)11554-0.070-0.3411Yes
319IL7IL7
Entrez,  Source
interleukin 711588-0.071-0.3409Yes
320NR1H2NR1H2
Entrez,  Source
nuclear receptor subfamily 1, group H, member 211613-0.073-0.3399Yes
321NRG1NRG1
Entrez,  Source
neuregulin 111626-0.073-0.3379Yes
322CDKN1BCDKN1B
Entrez,  Source
cyclin-dependent kinase inhibitor 1B (p27, Kip1)11651-0.074-0.3369Yes
323BREBRE
Entrez,  Source
brain and reproductive organ-expressed (TNFRSF1A modulator)11655-0.074-0.3342Yes
324GSK3BGSK3B
Entrez,  Source
glycogen synthase kinase 3 beta11670-0.074-0.3324Yes
325KHDRBS1KHDRBS1
Entrez,  Source
KH domain containing, RNA binding, signal transduction associated 111672-0.074-0.3295Yes
326EIF2AK1EIF2AK1
Entrez,  Source
eukaryotic translation initiation factor 2-alpha kinase 111677-0.075-0.3269Yes
327KLK8KLK8
Entrez,  Source
kallikrein 8 (neuropsin/ovasin)11700-0.075-0.3257Yes
328CDKN2DCDKN2D
Entrez,  Source
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)11809-0.080-0.3309Yes
329MAPRE1MAPRE1
Entrez,  Source
microtubule-associated protein, RP/EB family, member 111845-0.081-0.3304Yes
330CTBP2CTBP2
Entrez,  Source
C-terminal binding protein 211872-0.082-0.3292Yes
331HDAC7AHDAC7A
Entrez,  Source
histone deacetylase 7A11917-0.084-0.3293Yes
332CDH13CDH13
Entrez,  Source
cadherin 13, H-cadherin (heart)11996-0.087-0.3319Yes
333CASP3CASP3
Entrez,  Source
caspase 3, apoptosis-related cysteine peptidase12003-0.087-0.3290Yes
334CDKN2ACDKN2A
Entrez,  Source
cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)12064-0.090-0.3301Yes
335PAWRPAWR
Entrez,  Source
PRKC, apoptosis, WT1, regulator12073-0.090-0.3272Yes
336HDAC5HDAC5
Entrez,  Source
histone deacetylase 512129-0.093-0.3278Yes
337FABP3FABP3
Entrez,  Source
fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)12159-0.094-0.3263Yes
338NOL3NOL3
Entrez,  Source
nucleolar protein 3 (apoptosis repressor with CARD domain)12185-0.096-0.3245Yes
339CFL1CFL1
Entrez,  Source
cofilin 1 (non-muscle)12205-0.097-0.3221Yes
340USH2AUSH2A
Entrez,  Source
Usher syndrome 2A (autosomal recessive, mild)12216-0.098-0.3191Yes
341GSNGSN
Entrez,  Source
gelsolin (amyloidosis, Finnish type)12230-0.098-0.3162Yes
342PDCD4PDCD4
Entrez,  Source
programmed cell death 4 (neoplastic transformation inhibitor)12282-0.102-0.3161Yes
343PTPRCPTPRC
Entrez,  Source
protein tyrosine phosphatase, receptor type, C12324-0.105-0.3152Yes
344AMIGO2AMIGO2
Entrez,  Source
adhesion molecule with Ig-like domain 212343-0.107-0.3124Yes
345ABI1ABI1
Entrez,  Source
abl-interactor 112376-0.109-0.3106Yes
346ANXA4ANXA4
Entrez,  Source
annexin A412446-0.114-0.3114Yes
347DCBLD2DCBLD2
Entrez,  Source
discoidin, CUB and LCCL domain containing 212485-0.117-0.3098Yes
348MAGED1MAGED1
Entrez,  Source
melanoma antigen family D, 112552-0.121-0.3101Yes
349PPT1PPT1
Entrez,  Source
palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile)12619-0.127-0.3102Yes
350CLASP1CLASP1
Entrez,  Source
cytoplasmic linker associated protein 112638-0.129-0.3066Yes
351BMP2BMP2
Entrez,  Source
bone morphogenetic protein 212648-0.130-0.3022Yes
352SIRT2SIRT2
Entrez,  Source
sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae)12702-0.135-0.3010Yes
353BIRC3BIRC3
Entrez,  Source
baculoviral IAP repeat-containing 312722-0.137-0.2970Yes
354TM4SF4TM4SF4
Entrez,  Source
transmembrane 4 L six family member 412767-0.144-0.2948Yes
355VHLVHL
Entrez,  Source
von Hippel-Lindau tumor suppressor12780-0.145-0.2900Yes
356BRCA1BRCA1
Entrez,  Source
breast cancer 1, early onset12787-0.146-0.2848Yes
357BNIP3LBNIP3L
Entrez,  Source
BCL2/adenovirus E1B 19kDa interacting protein 3-like12870-0.160-0.2848Yes
358CLCF1CLCF1
Entrez,  Source
cardiotrophin-like cytokine factor 112884-0.162-0.2795Yes
359ANXA5ANXA5
Entrez,  Source
annexin A512886-0.162-0.2732Yes
360TAX1BP3TAX1BP3
Entrez,  Source
Tax1 (human T-cell leukemia virus type I) binding protein 312900-0.165-0.2678Yes
361CHEK1CHEK1
Entrez,  Source
CHK1 checkpoint homolog (S. pombe)12915-0.168-0.2622Yes
362DDAH2DDAH2
Entrez,  Source
dimethylarginine dimethylaminohydrolase 212970-0.181-0.2593Yes
363PRKRAPRKRA
Entrez,  Source
protein kinase, interferon-inducible double stranded RNA dependent activator13016-0.194-0.2552Yes
364TIMELESSTIMELESS
Entrez,  Source
timeless homolog (Drosophila)13018-0.194-0.2477Yes
365E2F1E2F1
Entrez,  Source
E2F transcription factor 113022-0.195-0.2402Yes
366FRKFRK
Entrez,  Source
fyn-related kinase13059-0.212-0.2347Yes
367ETS1ETS1
Entrez,  Source
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)13063-0.214-0.2265Yes
368FABP7FABP7
Entrez,  Source
fatty acid binding protein 7, brain13148-0.256-0.2230Yes
369S100A11S100A11
Entrez,  Source
S100 calcium binding protein A1113163-0.267-0.2136Yes
370RTN4RTN4
Entrez,  Source
reticulon 413167-0.269-0.2033Yes
371GPNMBGPNMB
Entrez,  Source
glycoprotein (transmembrane) nmb13168-0.269-0.1927Yes
372FSTFST
Entrez,  Source
follistatin13176-0.277-0.1824Yes
373TCEAL1TCEAL1
Entrez,  Source
transcription elongation factor A (SII)-like 113184-0.284-0.1718Yes
374TIMP1TIMP1
Entrez,  Source
TIMP metallopeptidase inhibitor 113187-0.286-0.1607Yes
375CRYABCRYAB
Entrez,  Source
crystallin, alpha B13206-0.298-0.1505Yes
376ID3ID3
Entrez,  Source
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein13220-0.314-0.1391Yes
377PEA15PEA15
Entrez,  Source
phosphoprotein enriched in astrocytes 1513282-0.412-0.1277Yes
378ACTN1ACTN1
Entrez,  Source
actinin, alpha 113303-0.473-0.1107Yes
379IGFBP7IGFBP7
Entrez,  Source
insulin-like growth factor binding protein 713304-0.474-0.0921Yes
380SERPINE1SERPINE1
Entrez,  Source
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 113308-0.484-0.0733Yes
381ANXA1ANXA1
Entrez,  Source
annexin A113312-0.498-0.0540Yes
382CCL2CCL2
Entrez,  Source
chemokine (C-C motif) ligand 213326-0.627-0.0305Yes
383CD24CD24
Entrez,  Source
CD24 molecule13336-0.8060.0005Yes
Table: GSEA details [plain text format]



Fig 2: NEGATIVE_REGULATION_OF_BIOLOGICAL_PROCESS   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: NEGATIVE_REGULATION_OF_BIOLOGICAL_PROCESS: Random ES distribution   
Gene set null distribution of ES for NEGATIVE_REGULATION_OF_BIOLOGICAL_PROCESS