Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_48h_versus_single_gel_48h.class.cls
#double_gel_48h_versus_single_gel_48h_repos
Phenotypeclass.cls#double_gel_48h_versus_single_gel_48h_repos
Upregulated in classdouble_gel_48h
GeneSetNETPATH_IL_2_PATHWAY_UP
Enrichment Score (ES)0.31751603
Normalized Enrichment Score (NES)1.4773637
Nominal p-value0.0
FDR q-value0.15929651
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: NETPATH_IL_2_PATHWAY_UP   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1FOSFOS
Entrez,  Source
v-fos FBJ murine osteosarcoma viral oncogene homolog01.0120.0501Yes
2EDG1EDG1
Entrez,  Source
endothelial differentiation, sphingolipid G-protein-coupled receptor, 130.5660.0780Yes
3PEMTPEMT
Entrez,  Source
phosphatidylethanolamine N-methyltransferase40.4910.1024Yes
4IDI1IDI1
Entrez,  Source
isopentenyl-diphosphate delta isomerase 1130.3820.1207Yes
5SLCO2B1SLCO2B1
Entrez,  Source
solute carrier organic anion transporter family, member 2B1380.2990.1337Yes
6CYP51A1CYP51A1
Entrez,  Source
cytochrome P450, family 51, subfamily A, polypeptide 1560.2770.1462Yes
7SQLESQLE
Entrez,  Source
squalene epoxidase1120.2140.1526Yes
8GADD45GGADD45G
Entrez,  Source
growth arrest and DNA-damage-inducible, gamma1600.1890.1584Yes
9ACAA2ACAA2
Entrez,  Source
acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase)1630.1870.1675Yes
10GSTA2GSTA2
Entrez,  Source
glutathione S-transferase A21880.1750.1744Yes
11GOT1GOT1
Entrez,  Source
glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)1970.1730.1823Yes
12GCKGCK
Entrez,  Source
glucokinase (hexokinase 4, maturity onset diabetes of the young 2)2180.1700.1892Yes
13GPC3GPC3
Entrez,  Source
glypican 32210.1670.1973Yes
14PTGER3PTGER3
Entrez,  Source
prostaglandin E receptor 3 (subtype EP3)2440.1610.2036Yes
15SLC30A1SLC30A1
Entrez,  Source
solute carrier family 30 (zinc transporter), member 12630.1560.2100Yes
16CD40LGCD40LG
Entrez,  Source
CD40 ligand (TNF superfamily, member 5, hyper-IgM syndrome)3170.1480.2132Yes
17RGS16RGS16
Entrez,  Source
regulator of G-protein signalling 163350.1440.2191Yes
18TERTTERT
Entrez,  Source
telomerase reverse transcriptase3740.1380.2230Yes
19GALEGALE
Entrez,  Source
UDP-galactose-4-epimerase4070.1340.2272Yes
20CCR1CCR1
Entrez,  Source
chemokine (C-C motif) receptor 14100.1340.2337Yes
21IL2RGIL2RG
Entrez,  Source
interleukin 2 receptor, gamma (severe combined immunodeficiency)5030.1250.2329Yes
22ACSL1ACSL1
Entrez,  Source
acyl-CoA synthetase long-chain family member 15640.1210.2343Yes
23GNRHRGNRHR
Entrez,  Source
gonadotropin-releasing hormone receptor6840.1130.2307Yes
24LTBLTB
Entrez,  Source
lymphotoxin beta (TNF superfamily, member 3)7190.1110.2336Yes
25IFIT1IFIT1
Entrez,  Source
interferon-induced protein with tetratricopeptide repeats 17500.1090.2367Yes
26MALLMALL
Entrez,  Source
mal, T-cell differentiation protein-like7540.1090.2419Yes
27BHLHB2BHLHB2
Entrez,  Source
basic helix-loop-helix domain containing, class B, 27660.1080.2464Yes
28CASP1CASP1
Entrez,  Source
caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)8090.1060.2485Yes
29EIF1EIF1
Entrez,  Source
eukaryotic translation initiation factor 18960.1030.2470Yes
30CEACAM1CEACAM1
Entrez,  Source
carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)9320.1010.2493Yes
31LDLRLDLR
Entrez,  Source
low density lipoprotein receptor (familial hypercholesterolemia)9980.0980.2492Yes
32KLRC1KLRC1
Entrez,  Source
killer cell lectin-like receptor subfamily C, member 110710.0950.2483Yes
33PBEF1PBEF1
Entrez,  Source
pre-B-cell colony enhancing factor 110740.0940.2529Yes
34PTPN3PTPN3
Entrez,  Source
protein tyrosine phosphatase, non-receptor type 310850.0940.2568Yes
35GAD2GAD2
Entrez,  Source
glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)12120.0890.2515Yes
36DUSP4DUSP4
Entrez,  Source
dual specificity phosphatase 412250.0890.2550Yes
37BOP1BOP1
Entrez,  Source
block of proliferation 112300.0890.2591Yes
38MASP2MASP2
Entrez,  Source
mannan-binding lectin serine peptidase 212540.0880.2617Yes
39PIM1PIM1
Entrez,  Source
pim-1 oncogene12640.0870.2653Yes
40HPNHPN
Entrez,  Source
hepsin (transmembrane protease, serine 1)13030.0860.2667Yes
41NOLC1NOLC1
Entrez,  Source
nucleolar and coiled-body phosphoprotein 113530.0840.2671Yes
42ADRA1DADRA1D
Entrez,  Source
adrenergic, alpha-1D-, receptor13640.0840.2705Yes
43SLC25A20SLC25A20
Entrez,  Source
solute carrier family 25 (carnitine/acylcarnitine translocase), member 2013810.0830.2734Yes
44MTHFD1MTHFD1
Entrez,  Source
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase13920.0830.2767Yes
45RDH11RDH11
Entrez,  Source
retinol dehydrogenase 11 (all-trans/9-cis/11-cis)13950.0830.2807Yes
46ITGAMITGAM
Entrez,  Source
integrin, alpha M (complement component 3 receptor 3 subunit)14150.0820.2833Yes
47ATF5ATF5
Entrez,  Source
activating transcription factor 514590.0810.2840Yes
48NCR3NCR3
Entrez,  Source
natural cytotoxicity triggering receptor 314800.0800.2864Yes
49IL1BIL1B
Entrez,  Source
interleukin 1, beta14950.0790.2893Yes
50TITF1TITF1
Entrez,  Source
thyroid transcription factor 114980.0790.2931Yes
51FASLGFASLG
Entrez,  Source
Fas ligand (TNF superfamily, member 6)15340.0790.2943Yes
52CX3CR1CX3CR1
Entrez,  Source
chemokine (C-X3-C motif) receptor 115820.0770.2945Yes
53CMAHCMAH
Entrez,  Source
cytidine monophosphate-N-acetylneuraminic acid hydroxylase (CMP-N-acetylneuraminate monooxygenase)16160.0770.2958Yes
54IL13IL13
Entrez,  Source
interleukin 1316580.0750.2964Yes
55STAT5ASTAT5A
Entrez,  Source
signal transducer and activator of transcription 5A16740.0750.2990Yes
56FYNFYN
Entrez,  Source
FYN oncogene related to SRC, FGR, YES16820.0750.3021Yes
57TTNTTN
Entrez,  Source
titin16950.0740.3049Yes
58NTRK1NTRK1
Entrez,  Source
neurotrophic tyrosine kinase, receptor, type 117450.0730.3048Yes
59TXKTXK
Entrez,  Source
TXK tyrosine kinase17620.0730.3072Yes
60SLC2A3SLC2A3
Entrez,  Source
solute carrier family 2 (facilitated glucose transporter), member 317690.0730.3103Yes
61VEGFVEGF
Entrez,  Source
vascular endothelial growth factor18830.0700.3052Yes
62IL12RB2IL12RB2
Entrez,  Source
interleukin 12 receptor, beta 218950.0700.3078Yes
63MYCMYC
Entrez,  Source
v-myc myelocytomatosis viral oncogene homolog (avian)18960.0700.3113Yes
64ADD2ADD2
Entrez,  Source
adducin 2 (beta)18970.0700.3147Yes
65YARSYARS
Entrez,  Source
tyrosyl-tRNA synthetase19070.0700.3175Yes
66PA2G4PA2G4
Entrez,  Source
proliferation-associated 2G4, 38kDa19580.0690.3171No
67PRKCEPRKCE
Entrez,  Source
protein kinase C, epsilon20080.0680.3167No
68MX1MX1
Entrez,  Source
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)21750.0640.3072No
69PTPN7PTPN7
Entrez,  Source
protein tyrosine phosphatase, non-receptor type 721810.0640.3100No
70CD53CD53
Entrez,  Source
CD53 molecule22030.0640.3116No
71RAF1RAF1
Entrez,  Source
v-raf-1 murine leukemia viral oncogene homolog 122840.0620.3086No
72CYP4F2CYP4F2
Entrez,  Source
cytochrome P450, family 4, subfamily F, polypeptide 222910.0620.3112No
73SOCS3SOCS3
Entrez,  Source
suppressor of cytokine signaling 323550.0610.3094No
74SLC7A5SLC7A5
Entrez,  Source
solute carrier family 7 (cationic amino acid transporter, y+ system), member 523960.0600.3093No
75IGJIGJ
Entrez,  Source
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides24720.0590.3065No
76NDUFV2NDUFV2
Entrez,  Source
NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa25030.0580.3071No
77KDRKDR
Entrez,  Source
kinase insert domain receptor (a type III receptor tyrosine kinase)25050.0580.3099No
78LIFLIF
Entrez,  Source
leukemia inhibitory factor (cholinergic differentiation factor)26600.0560.3009No
79FGF5FGF5
Entrez,  Source
fibroblast growth factor 526730.0560.3028No
80NFIL3NFIL3
Entrez,  Source
nuclear factor, interleukin 3 regulated26900.0550.3043No
81PTP4A1PTP4A1
Entrez,  Source
protein tyrosine phosphatase type IVA, member 128100.0530.2978No
82NRXN3NRXN3
Entrez,  Source
neurexin 329250.0510.2916No
83GPLD1GPLD1
Entrez,  Source
glycosylphosphatidylinositol specific phospholipase D129450.0510.2927No
84CACNA1CCACNA1C
Entrez,  Source
calcium channel, voltage-dependent, L type, alpha 1C subunit32520.0460.2716No
85KCNAB1KCNAB1
Entrez,  Source
potassium voltage-gated channel, shaker-related subfamily, beta member 133060.0460.2698No
86TXNRD1TXNRD1
Entrez,  Source
thioredoxin reductase 133420.0450.2694No
87NOL5ANOL5A
Entrez,  Source
nucleolar protein 5A (56kDa with KKE/D repeat)33460.0450.2714No
88CREMCREM
Entrez,  Source
cAMP responsive element modulator34060.0440.2691No
89ITPR2ITPR2
Entrez,  Source
inositol 1,4,5-triphosphate receptor, type 234680.0430.2666No
90PLAUPLAU
Entrez,  Source
plasminogen activator, urokinase35050.0430.2659No
91ATF4ATF4
Entrez,  Source
activating transcription factor 4 (tax-responsive enhancer element B67)35790.0420.2624No
92SSBP1SSBP1
Entrez,  Source
single-stranded DNA binding protein 135880.0420.2639No
93MMP16MMP16
Entrez,  Source
matrix metallopeptidase 16 (membrane-inserted)36330.0410.2626No
94HTR3AHTR3A
Entrez,  Source
5-hydroxytryptamine (serotonin) receptor 3A36370.0410.2644No
95AIF1AIF1
Entrez,  Source
allograft inflammatory factor 136790.0410.2633No
96NOS1APNOS1AP
Entrez,  Source
nitric oxide synthase 1 (neuronal) adaptor protein37860.0390.2571No
97SLC17A7SLC17A7
Entrez,  Source
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 738050.0390.2577No
98SRCSRC
Entrez,  Source
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)39180.0380.2510No
99TOP1TOP1
Entrez,  Source
topoisomerase (DNA) I39190.0380.2528No
100CCR5CCR5
Entrez,  Source
chemokine (C-C motif) receptor 539940.0360.2490No
101ABCE1ABCE1
Entrez,  Source
ATP-binding cassette, sub-family E (OABP), member 140930.0350.2432No
102IL2RBIL2RB
Entrez,  Source
interleukin 2 receptor, beta41910.0340.2375No
103PCNAPCNA
Entrez,  Source
proliferating cell nuclear antigen42580.0330.2341No
104BCL2BCL2
Entrez,  Source
B-cell CLL/lymphoma 243280.0320.2304No
105PFKFB3PFKFB3
Entrez,  Source
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 343970.0310.2268No
106MGST1MGST1
Entrez,  Source
microsomal glutathione S-transferase 144920.0300.2211No
107DKC1DKC1
Entrez,  Source
dyskeratosis congenita 1, dyskerin45230.0300.2202No
108USP15USP15
Entrez,  Source
ubiquitin specific peptidase 1545980.0290.2160No
109SLC7A7SLC7A7
Entrez,  Source
solute carrier family 7 (cationic amino acid transporter, y+ system), member 746000.0290.2174No
110CCR6CCR6
Entrez,  Source
chemokine (C-C motif) receptor 646220.0280.2172No
111TBX5TBX5
Entrez,  Source
T-box 546820.0280.2140No
112GZMBGZMB
Entrez,  Source
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)46880.0280.2150No
113CCL3CCL3
Entrez,  Source
chemokine (C-C motif) ligand 347060.0270.2151No
114IL4RIL4R
Entrez,  Source
interleukin 4 receptor47650.0270.2120No
115FASFAS
Entrez,  Source
Fas (TNF receptor superfamily, member 6)48360.0260.2079No
116JUNDJUND
Entrez,  Source
jun D proto-oncogene48840.0250.2055No
117MAPKAPK3MAPKAPK3
Entrez,  Source
mitogen-activated protein kinase-activated protein kinase 349260.0250.2036No
118UBE2NUBE2N
Entrez,  Source
ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)49600.0240.2023No
119MLLT3MLLT3
Entrez,  Source
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 350050.0240.2001No
120IL8RAIL8RA
Entrez,  Source
interleukin 8 receptor, alpha50080.0240.2011No
121STAT4STAT4
Entrez,  Source
signal transducer and activator of transcription 450650.0230.1980No
122PDIA3PDIA3
Entrez,  Source
protein disulfide isomerase family A, member 350840.0230.1978No
123IL6STIL6ST
Entrez,  Source
interleukin 6 signal transducer (gp130, oncostatin M receptor)52340.0210.1874No
124HNRPABHNRPAB
Entrez,  Source
heterogeneous nuclear ribonucleoprotein A/B52690.0210.1858No
125CSF1CSF1
Entrez,  Source
colony stimulating factor 1 (macrophage)53080.0200.1839No
126PDCD2PDCD2
Entrez,  Source
programmed cell death 253220.0200.1839No
127CASP9CASP9
Entrez,  Source
caspase 9, apoptosis-related cysteine peptidase53940.0190.1795No
128NME1NME1
Entrez,  Source
non-metastatic cells 1, protein (NM23A) expressed in54030.0190.1798No
129TARSTARS
Entrez,  Source
threonyl-tRNA synthetase55850.0170.1668No
130XBP1XBP1
Entrez,  Source
X-box binding protein 156080.0170.1660No
131CCND2CCND2
Entrez,  Source
cyclin D257710.0150.1543No
132GZMAGZMA
Entrez,  Source
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)57750.0150.1549No
133ADAM19ADAM19
Entrez,  Source
ADAM metallopeptidase domain 19 (meltrin beta)58300.0150.1515No
134CLTCCLTC
Entrez,  Source
clathrin, heavy chain (Hc)59070.0140.1463No
135GPX4GPX4
Entrez,  Source
glutathione peroxidase 4 (phospholipid hydroperoxidase)59170.0140.1463No
136NFICNFIC
Entrez,  Source
nuclear factor I/C (CCAAT-binding transcription factor)59240.0140.1465No
137GARSGARS
Entrez,  Source
glycyl-tRNA synthetase59290.0140.1469No
138PTGER2PTGER2
Entrez,  Source
prostaglandin E receptor 2 (subtype EP2), 53kDa60270.0130.1401No
139PRF1PRF1
Entrez,  Source
perforin 1 (pore forming protein)60870.0120.1362No
140EIF2S2EIF2S2
Entrez,  Source
eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa61600.0110.1312No
141OPCMLOPCML
Entrez,  Source
opioid binding protein/cell adhesion molecule-like62280.0110.1266No
142CPA3CPA3
Entrez,  Source
carboxypeptidase A3 (mast cell)62660.0100.1243No
143SOCS2SOCS2
Entrez,  Source
suppressor of cytokine signaling 264000.0090.1146No
144TLR4TLR4
Entrez,  Source
toll-like receptor 464530.0080.1110No
145SLC39A8SLC39A8
Entrez,  Source
solute carrier family 39 (zinc transporter), member 865730.0070.1022No
146MAP3K7IP2MAP3K7IP2
Entrez,  Source
mitogen-activated protein kinase kinase kinase 7 interacting protein 266110.0060.0997No
147DUSP11DUSP11
Entrez,  Source
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)66980.0050.0934No
148SC65SC65
Entrez,  Source
-67740.0040.0879No
149TNFTNF
Entrez,  Source
tumor necrosis factor (TNF superfamily, member 2)67780.0040.0879No
150MALMAL
Entrez,  Source
mal, T-cell differentiation protein67790.0040.0881No
151NR4A2NR4A2
Entrez,  Source
nuclear receptor subfamily 4, group A, member 267910.0040.0874No
152CTSCCTSC
Entrez,  Source
cathepsin C68060.0040.0866No
153TNFRSF4TNFRSF4
Entrez,  Source
tumor necrosis factor receptor superfamily, member 468310.0040.0849No
154STK17BSTK17B
Entrez,  Source
serine/threonine kinase 17b (apoptosis-inducing)68410.0040.0844No
155IL6IL6
Entrez,  Source
interleukin 6 (interferon, beta 2)68640.0040.0829No
156KARSKARS
Entrez,  Source
lysyl-tRNA synthetase68850.0030.0816No
157ARF6ARF6
Entrez,  Source
ADP-ribosylation factor 668990.0030.0807No
158GNG10GNG10
Entrez,  Source
guanine nucleotide binding protein (G protein), gamma 1069730.0020.0752No
159STAT5BSTAT5B
Entrez,  Source
signal transducer and activator of transcription 5B70240.0020.0715No
160IL10IL10
Entrez,  Source
interleukin 1070910.0010.0665No
161NKG7NKG7
Entrez,  Source
natural killer cell group 7 sequence7263-0.0010.0535No
162PRKCAPRKCA
Entrez,  Source
protein kinase C, alpha7310-0.0020.0500No
163PSMB1PSMB1
Entrez,  Source
proteasome (prosome, macropain) subunit, beta type, 17341-0.0020.0478No
164CRYMCRYM
Entrez,  Source
crystallin, mu7438-0.0030.0406No
165UPP1UPP1
Entrez,  Source
uridine phosphorylase 17441-0.0030.0406No
166ALDH3A1ALDH3A1
Entrez,  Source
aldehyde dehydrogenase 3 family, memberA17461-0.0030.0393No
167KLF6KLF6
Entrez,  Source
Kruppel-like factor 67545-0.0040.0332No
168ODC1ODC1
Entrez,  Source
ornithine decarboxylase 17596-0.0050.0296No
169GAPDHGAPDH
Entrez,  Source
glyceraldehyde-3-phosphate dehydrogenase7606-0.0050.0292No
170ASNSASNS
Entrez,  Source
asparagine synthetase7614-0.0050.0289No
171GATA3GATA3
Entrez,  Source
GATA binding protein 37644-0.0050.0269No
172CCL4CCL4
Entrez,  Source
chemokine (C-C motif) ligand 47645-0.0050.0272No
173TRHTRH
Entrez,  Source
thyrotropin-releasing hormone7651-0.0050.0270No
174ATP1B1ATP1B1
Entrez,  Source
ATPase, Na+/K+ transporting, beta 1 polypeptide7708-0.0060.0231No
175TCEB1TCEB1
Entrez,  Source
transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)7731-0.0060.0217No
176ADMRADMR
Entrez,  Source
adrenomedullin receptor7749-0.0060.0207No
177WARSWARS
Entrez,  Source
tryptophanyl-tRNA synthetase7995-0.0090.0024No
178FUBP1FUBP1
Entrez,  Source
far upstream element (FUSE) binding protein 17997-0.0090.0028No
179JUNJUN
Entrez,  Source
jun oncogene8081-0.010-0.0030No
180RGS1RGS1
Entrez,  Source
regulator of G-protein signalling 18082-0.010-0.0025No
181ARHGDIAARHGDIA
Entrez,  Source
Rho GDP dissociation inhibitor (GDI) alpha8158-0.011-0.0077No
182IMMTIMMT
Entrez,  Source
inner membrane protein, mitochondrial (mitofilin)8340-0.013-0.0209No
183DUSP5DUSP5
Entrez,  Source
dual specificity phosphatase 58419-0.014-0.0261No
184ST13ST13
Entrez,  Source
suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)8448-0.015-0.0275No
185CFLARCFLAR
Entrez,  Source
CASP8 and FADD-like apoptosis regulator8465-0.015-0.0280No
186LTALTA
Entrez,  Source
lymphotoxin alpha (TNF superfamily, member 1)8598-0.017-0.0372No
187DPP4DPP4
Entrez,  Source
dipeptidyl-peptidase 4 (CD26, adenosine deaminase complexing protein 2)8651-0.017-0.0404No
188TMF1TMF1
Entrez,  Source
TATA element modulatory factor 18657-0.018-0.0399No
189ICAM1ICAM1
Entrez,  Source
intercellular adhesion molecule 1 (CD54), human rhinovirus receptor8686-0.018-0.0411No
190DAXXDAXX
Entrez,  Source
death-associated protein 68710-0.018-0.0420No
191PTPRRPTPRR
Entrez,  Source
protein tyrosine phosphatase, receptor type, R8741-0.018-0.0434No
192RGS19RGS19
Entrez,  Source
regulator of G-protein signalling 198758-0.019-0.0437No
193CSRP3CSRP3
Entrez,  Source
cysteine and glycine-rich protein 3 (cardiac LIM protein)8812-0.019-0.0468No
194ATICATIC
Entrez,  Source
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase8886-0.020-0.0513No
195SH2D2ASH2D2A
Entrez,  Source
SH2 domain protein 2A8984-0.022-0.0577No
196SFPQSFPQ
Entrez,  Source
splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated)9009-0.022-0.0584No
197STAT1STAT1
Entrez,  Source
signal transducer and activator of transcription 1, 91kDa9067-0.023-0.0617No
198FRMD4BFRMD4B
Entrez,  Source
FERM domain containing 4B9173-0.024-0.0685No
199STIP1STIP1
Entrez,  Source
stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing protein)9205-0.024-0.0697No
200CSF2CSF2
Entrez,  Source
colony stimulating factor 2 (granulocyte-macrophage)9237-0.025-0.0708No
201RBM3RBM3
Entrez,  Source
RNA binding motif (RNP1, RRM) protein 39354-0.027-0.0783No
202ID2ID2
Entrez,  Source
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein9384-0.027-0.0792No
203IFNGIFNG
Entrez,  Source
interferon, gamma9423-0.028-0.0807No
204IL2RAIL2RA
Entrez,  Source
interleukin 2 receptor, alpha9496-0.029-0.0848No
205LIMK2LIMK2
Entrez,  Source
LIM domain kinase 29546-0.030-0.0871No
206PLXNB2PLXNB2
Entrez,  Source
plexin B29766-0.033-0.1022No
207CYP7B1CYP7B1
Entrez,  Source
cytochrome P450, family 7, subfamily B, polypeptide 19803-0.033-0.1033No
208LCP2LCP2
Entrez,  Source
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)9952-0.036-0.1129No
209SOCS1SOCS1
Entrez,  Source
suppressor of cytokine signaling 110039-0.037-0.1176No
210PAICSPAICS
Entrez,  Source
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase10082-0.038-0.1189No
211CCRKCCRK
Entrez,  Source
cell cycle related kinase10169-0.039-0.1235No
212DPM2DPM2
Entrez,  Source
dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit10215-0.040-0.1250No
213TPI1TPI1
Entrez,  Source
triosephosphate isomerase 110267-0.041-0.1269No
214IL1R1IL1R1
Entrez,  Source
interleukin 1 receptor, type I10292-0.041-0.1266No
215CARD9CARD9
Entrez,  Source
caspase recruitment domain family, member 910306-0.041-0.1256No
216IFITM3IFITM3
Entrez,  Source
interferon induced transmembrane protein 3 (1-8U)10326-0.042-0.1250No
217CISHCISH
Entrez,  Source
cytokine inducible SH2-containing protein10352-0.042-0.1248No
218PER2PER2
Entrez,  Source
period homolog 2 (Drosophila)10374-0.043-0.1243No
219IER3IER3
Entrez,  Source
immediate early response 310439-0.044-0.1270No
220BCL2L1BCL2L1
Entrez,  Source
BCL2-like 110657-0.048-0.1412No
221PAX4PAX4
Entrez,  Source
paired box gene 410725-0.050-0.1438No
222SNAP25SNAP25
Entrez,  Source
synaptosomal-associated protein, 25kDa10791-0.051-0.1462No
223CCR2CCR2
Entrez,  Source
chemokine (C-C motif) receptor 211014-0.056-0.1604No
224MNAT1MNAT1
Entrez,  Source
menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis)11046-0.057-0.1600No
225PAK1PAK1
Entrez,  Source
p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)11055-0.057-0.1578No
226CTSHCTSH
Entrez,  Source
cathepsin H11083-0.058-0.1570No
227PPAP2APPAP2A
Entrez,  Source
phosphatidic acid phosphatase type 2A11084-0.058-0.1541No
228NMINMI
Entrez,  Source
N-myc (and STAT) interactor11093-0.058-0.1519No
229BTG3BTG3
Entrez,  Source
BTG family, member 311098-0.058-0.1493No
230RELARELA
Entrez,  Source
v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian)11138-0.059-0.1494No
231IL5IL5
Entrez,  Source
interleukin 5 (colony-stimulating factor, eosinophil)11177-0.060-0.1493No
232ACTBACTB
Entrez,  Source
actin, beta11264-0.061-0.1529No
233AHRAHR
Entrez,  Source
aryl hydrocarbon receptor11457-0.067-0.1643No
234NFKB1NFKB1
Entrez,  Source
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105)11510-0.069-0.1648No
235SLC1A5SLC1A5
Entrez,  Source
solute carrier family 1 (neutral amino acid transporter), member 511601-0.072-0.1681No
236FLOT1FLOT1
Entrez,  Source
flotillin 111724-0.076-0.1737No
237PRKXPRKX
Entrez,  Source
protein kinase, X-linked11950-0.085-0.1867No
238CASP3CASP3
Entrez,  Source
caspase 3, apoptosis-related cysteine peptidase12003-0.087-0.1864No
239LAPTM4BLAPTM4B
Entrez,  Source
lysosomal associated protein transmembrane 4 beta12012-0.088-0.1826No
240LYNLYN
Entrez,  Source
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog12083-0.091-0.1835No
241MAT2AMAT2A
Entrez,  Source
methionine adenosyltransferase II, alpha12127-0.093-0.1822No
242CBFBCBFB
Entrez,  Source
core-binding factor, beta subunit12204-0.097-0.1832No
243MAPKAPK2MAPKAPK2
Entrez,  Source
mitogen-activated protein kinase-activated protein kinase 212240-0.099-0.1810No
244VAMP5VAMP5
Entrez,  Source
vesicle-associated membrane protein 5 (myobrevin)12296-0.103-0.1800No
245PTPRCPTPRC
Entrez,  Source
protein tyrosine phosphatase, receptor type, C12324-0.105-0.1769No
246DUSP6DUSP6
Entrez,  Source
dual specificity phosphatase 612330-0.106-0.1720No
247ENPEPENPEP
Entrez,  Source
glutamyl aminopeptidase (aminopeptidase A)12336-0.106-0.1672No
248SRD5A1SRD5A1
Entrez,  Source
steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)12386-0.110-0.1655No
249SGKSGK
Entrez,  Source
serum/glucocorticoid regulated kinase12473-0.116-0.1663No
250IRF1IRF1
Entrez,  Source
interferon regulatory factor 112531-0.120-0.1647No
251PRKCDPRKCD
Entrez,  Source
protein kinase C, delta12535-0.120-0.1590No
252TRAFD1TRAFD1
Entrez,  Source
TRAF-type zinc finger domain containing 112558-0.122-0.1546No
253PLAURPLAUR
Entrez,  Source
plasminogen activator, urokinase receptor12561-0.122-0.1487No
254AP3M2AP3M2
Entrez,  Source
adaptor-related protein complex 3, mu 2 subunit12761-0.143-0.1569No
255IL1RAPIL1RAP
Entrez,  Source
interleukin 1 receptor accessory protein12771-0.144-0.1504No
256IFI44IFI44
Entrez,  Source
interferon-induced protein 4412808-0.149-0.1458No
257RALBRALB
Entrez,  Source
v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)12865-0.159-0.1422No
258PDE4BPDE4B
Entrez,  Source
phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila)12954-0.177-0.1402No
259VIMVIM
Entrez,  Source
vimentin13040-0.204-0.1366No
260LDHBLDHB
Entrez,  Source
lactate dehydrogenase B13053-0.209-0.1272No
261ETS1ETS1
Entrez,  Source
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)13063-0.214-0.1173No
262ADRA1BADRA1B
Entrez,  Source
adrenergic, alpha-1B-, receptor13101-0.233-0.1085No
263RRAS2RRAS2
Entrez,  Source
related RAS viral (r-ras) oncogene homolog 213125-0.244-0.0982No
264RAB31RAB31
Entrez,  Source
RAB31, member RAS oncogene family13200-0.292-0.0894No
265TIMP2TIMP2
Entrez,  Source
TIMP metallopeptidase inhibitor 213228-0.323-0.0755No
266CCND1CCND1
Entrez,  Source
cyclin D113250-0.352-0.0596No
267S100A4S100A4
Entrez,  Source
S100 calcium binding protein A413279-0.400-0.0420No
268CD69CD69
Entrez,  Source
CD69 molecule13297-0.457-0.0206No
269SERPINE1SERPINE1
Entrez,  Source
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 113308-0.4840.0026No
Table: GSEA details [plain text format]



Fig 2: NETPATH_IL_2_PATHWAY_UP   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: NETPATH_IL_2_PATHWAY_UP: Random ES distribution   
Gene set null distribution of ES for NETPATH_IL_2_PATHWAY_UP