Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | NETPATH_IL_4_PATHWAY_DOWN |
| Enrichment Score (ES) | -0.5270148 |
| Normalized Enrichment Score (NES) | -1.7265176 |
| Nominal p-value | 0.0032948928 |
| FDR q-value | 0.05533816 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | DDIT4 | DDIT4 Entrez, Source | DNA-damage-inducible transcript 4 | 134 | 0.198 | 0.0276 | No |
| 2 | MMP3 | MMP3 Entrez, Source | matrix metallopeptidase 3 (stromelysin 1, progelatinase) | 351 | 0.142 | 0.0382 | No |
| 3 | ALOX5AP | ALOX5AP Entrez, Source | arachidonate 5-lipoxygenase-activating protein | 583 | 0.119 | 0.0434 | No |
| 4 | KLF15 | KLF15 Entrez, Source | Kruppel-like factor 15 | 600 | 0.118 | 0.0646 | No |
| 5 | LTB | LTB Entrez, Source | lymphotoxin beta (TNF superfamily, member 3) | 719 | 0.111 | 0.0767 | No |
| 6 | PTGS2 | PTGS2 Entrez, Source | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 886 | 0.103 | 0.0838 | No |
| 7 | MFNG | MFNG Entrez, Source | manic fringe homolog (Drosophila) | 1545 | 0.078 | 0.0492 | No |
| 8 | KLK6 | KLK6 Entrez, Source | kallikrein 6 (neurosin, zyme) | 1901 | 0.070 | 0.0357 | No |
| 9 | MX1 | MX1 Entrez, Source | myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) | 2175 | 0.064 | 0.0274 | No |
| 10 | ITPKB | ITPKB Entrez, Source | inositol 1,4,5-trisphosphate 3-kinase B | 2227 | 0.064 | 0.0356 | No |
| 11 | NDRG4 | NDRG4 Entrez, Source | NDRG family member 4 | 2272 | 0.063 | 0.0442 | No |
| 12 | CD9 | CD9 Entrez, Source | CD9 molecule | 2527 | 0.058 | 0.0361 | No |
| 13 | SPP1 | SPP1 Entrez, Source | secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) | 2593 | 0.057 | 0.0420 | No |
| 14 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 2688 | 0.055 | 0.0455 | No |
| 15 | CHI3L1 | CHI3L1 Entrez, Source | chitinase 3-like 1 (cartilage glycoprotein-39) | 2878 | 0.052 | 0.0411 | No |
| 16 | GJA4 | GJA4 Entrez, Source | gap junction protein, alpha 4, 37kDa (connexin 37) | 3292 | 0.046 | 0.0187 | No |
| 17 | LAMA3 | LAMA3 Entrez, Source | laminin, alpha 3 | 3419 | 0.044 | 0.0176 | No |
| 18 | CAV3 | CAV3 Entrez, Source | caveolin 3 | 3663 | 0.041 | 0.0071 | No |
| 19 | TRPV5 | TRPV5 Entrez, Source | transient receptor potential cation channel, subfamily V, member 5 | 4500 | 0.030 | -0.0501 | No |
| 20 | ALOX5 | ALOX5 Entrez, Source | arachidonate 5-lipoxygenase | 4818 | 0.026 | -0.0690 | No |
| 21 | CHST10 | CHST10 Entrez, Source | carbohydrate sulfotransferase 10 | 5161 | 0.022 | -0.0906 | No |
| 22 | LTB4R | LTB4R Entrez, Source | leukotriene B4 receptor | 5295 | 0.020 | -0.0967 | No |
| 23 | GZMA | GZMA Entrez, Source | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | 5775 | 0.015 | -0.1299 | No |
| 24 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 5802 | 0.015 | -0.1290 | No |
| 25 | KCNN2 | KCNN2 Entrez, Source | potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2 | 5943 | 0.013 | -0.1370 | No |
| 26 | TLR4 | TLR4 Entrez, Source | toll-like receptor 4 | 6453 | 0.008 | -0.1738 | No |
| 27 | TNF | TNF Entrez, Source | tumor necrosis factor (TNF superfamily, member 2) | 6778 | 0.004 | -0.1973 | No |
| 28 | IL6 | IL6 Entrez, Source | interleukin 6 (interferon, beta 2) | 6864 | 0.004 | -0.2031 | No |
| 29 | TLR2 | TLR2 Entrez, Source | toll-like receptor 2 | 6981 | 0.002 | -0.2114 | No |
| 30 | UBE2L6 | UBE2L6 Entrez, Source | ubiquitin-conjugating enzyme E2L 6 | 8567 | -0.016 | -0.3275 | No |
| 31 | CYSLTR2 | CYSLTR2 Entrez, Source | cysteinyl leukotriene receptor 2 | 8668 | -0.018 | -0.3317 | No |
| 32 | ICAM1 | ICAM1 Entrez, Source | intercellular adhesion molecule 1 (CD54), human rhinovirus receptor | 8686 | -0.018 | -0.3296 | No |
| 33 | CLTB | CLTB Entrez, Source | clathrin, light chain (Lcb) | 8851 | -0.020 | -0.3382 | No |
| 34 | LPL | LPL Entrez, Source | lipoprotein lipase | 8894 | -0.020 | -0.3375 | No |
| 35 | STAT1 | STAT1 Entrez, Source | signal transducer and activator of transcription 1, 91kDa | 9067 | -0.023 | -0.3461 | No |
| 36 | IL2RA | IL2RA Entrez, Source | interleukin 2 receptor, alpha | 9496 | -0.029 | -0.3728 | No |
| 37 | KIT | KIT Entrez, Source | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | 9974 | -0.036 | -0.4019 | No |
| 38 | NFKBIA | NFKBIA Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 10388 | -0.043 | -0.4247 | No |
| 39 | GADD45B | GADD45B Entrez, Source | growth arrest and DNA-damage-inducible, beta | 10614 | -0.047 | -0.4327 | No |
| 40 | IL18 | IL18 Entrez, Source | interleukin 18 (interferon-gamma-inducing factor) | 10944 | -0.055 | -0.4471 | No |
| 41 | RAB11B | RAB11B Entrez, Source | RAB11B, member RAS oncogene family | 10950 | -0.055 | -0.4370 | No |
| 42 | CDKN1B | CDKN1B Entrez, Source | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 11651 | -0.074 | -0.4757 | No |
| 43 | LITAF | LITAF Entrez, Source | lipopolysaccharide-induced TNF factor | 11763 | -0.078 | -0.4693 | No |
| 44 | IRF1 | IRF1 Entrez, Source | interferon regulatory factor 1 | 12531 | -0.120 | -0.5043 | Yes |
| 45 | NINJ1 | NINJ1 Entrez, Source | ninjurin 1 | 12752 | -0.141 | -0.4940 | Yes |
| 46 | VIM | VIM Entrez, Source | vimentin | 13040 | -0.204 | -0.4770 | Yes |
| 47 | LGALS2 | LGALS2 Entrez, Source | lectin, galactoside-binding, soluble, 2 (galectin 2) | 13064 | -0.214 | -0.4381 | Yes |
| 48 | TIMP1 | TIMP1 Entrez, Source | TIMP metallopeptidase inhibitor 1 | 13187 | -0.286 | -0.3931 | Yes |
| 49 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 13220 | -0.314 | -0.3359 | Yes |
| 50 | CXCL2 | CXCL2 Entrez, Source | chemokine (C-X-C motif) ligand 2 | 13254 | -0.355 | -0.2710 | Yes |
| 51 | CCL20 | CCL20 Entrez, Source | chemokine (C-C motif) ligand 20 | 13267 | -0.380 | -0.1997 | Yes |
| 52 | GBP2 | GBP2 Entrez, Source | guanylate binding protein 2, interferon-inducible | 13295 | -0.454 | -0.1155 | Yes |
| 53 | CCL2 | CCL2 Entrez, Source | chemokine (C-C motif) ligand 2 | 13326 | -0.627 | 0.0012 | Yes |
