Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | OXIDOREDUCTASE_ACTIVITY__ACTING_ON_CH_OH_GROUP_OF_DONORS |
| Enrichment Score (ES) | 0.5613004 |
| Normalized Enrichment Score (NES) | 1.8966669 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.016881036 |
| FWER p-Value | 0.561 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | EHHADH | EHHADH Entrez, Source | enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase | 6 | 0.447 | 0.1444 | Yes |
| 2 | HSD17B7 | HSD17B7 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 7 | 9 | 0.428 | 0.2830 | Yes |
| 3 | ADH7 | ADH7 Entrez, Source | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide | 19 | 0.354 | 0.3971 | Yes |
| 4 | MIOX | MIOX Entrez, Source | myo-inositol oxygenase | 289 | 0.151 | 0.4258 | Yes |
| 5 | GPD1 | GPD1 Entrez, Source | glycerol-3-phosphate dehydrogenase 1 (soluble) | 555 | 0.121 | 0.4451 | Yes |
| 6 | AKR7A2 | AKR7A2 Entrez, Source | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 712 | 0.111 | 0.4694 | Yes |
| 7 | AKR1B10 | AKR1B10 Entrez, Source | aldo-keto reductase family 1, member B10 (aldose reductase) | 1081 | 0.094 | 0.4722 | Yes |
| 8 | RDH11 | RDH11 Entrez, Source | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) | 1395 | 0.083 | 0.4756 | Yes |
| 9 | ADH6 | ADH6 Entrez, Source | alcohol dehydrogenase 6 (class V) | 1443 | 0.081 | 0.4984 | Yes |
| 10 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 1493 | 0.080 | 0.5205 | Yes |
| 11 | UGDH | UGDH Entrez, Source | UDP-glucose dehydrogenase | 1562 | 0.078 | 0.5406 | Yes |
| 12 | NSDHL | NSDHL Entrez, Source | NAD(P) dependent steroid dehydrogenase-like | 1768 | 0.073 | 0.5488 | Yes |
| 13 | AKR7A3 | AKR7A3 Entrez, Source | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | 1904 | 0.070 | 0.5613 | Yes |
| 14 | HSD3B1 | HSD3B1 Entrez, Source | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 | 2646 | 0.056 | 0.5238 | No |
| 15 | MDH1 | MDH1 Entrez, Source | malate dehydrogenase 1, NAD (soluble) | 2853 | 0.052 | 0.5253 | No |
| 16 | DHRS9 | DHRS9 Entrez, Source | dehydrogenase/reductase (SDR family) member 9 | 3288 | 0.046 | 0.5075 | No |
| 17 | IMPDH2 | IMPDH2 Entrez, Source | IMP (inosine monophosphate) dehydrogenase 2 | 3648 | 0.041 | 0.4939 | No |
| 18 | IDH3G | IDH3G Entrez, Source | isocitrate dehydrogenase 3 (NAD+) gamma | 3649 | 0.041 | 0.5072 | No |
| 19 | HPGD | HPGD Entrez, Source | hydroxyprostaglandin dehydrogenase 15-(NAD) | 3915 | 0.038 | 0.4995 | No |
| 20 | IDH1 | IDH1 Entrez, Source | isocitrate dehydrogenase 1 (NADP+), soluble | 3953 | 0.037 | 0.5087 | No |
| 21 | GPD2 | GPD2 Entrez, Source | glycerol-3-phosphate dehydrogenase 2 (mitochondrial) | 3968 | 0.037 | 0.5196 | No |
| 22 | HADHB | HADHB Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit | 4313 | 0.032 | 0.5043 | No |
| 23 | HSD17B4 | HSD17B4 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 4 | 4370 | 0.032 | 0.5103 | No |
| 24 | BDH1 | BDH1 Entrez, Source | 3-hydroxybutyrate dehydrogenase, type 1 | 4679 | 0.028 | 0.4962 | No |
| 25 | HAO2 | HAO2 Entrez, Source | hydroxyacid oxidase 2 (long chain) | 4991 | 0.024 | 0.4806 | No |
| 26 | HADHA | HADHA Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit | 5156 | 0.022 | 0.4754 | No |
| 27 | IDH3B | IDH3B Entrez, Source | isocitrate dehydrogenase 3 (NAD+) beta | 6092 | 0.012 | 0.4090 | No |
| 28 | ADH4 | ADH4 Entrez, Source | alcohol dehydrogenase 4 (class II), pi polypeptide | 6235 | 0.011 | 0.4017 | No |
| 29 | AKR1A1 | AKR1A1 Entrez, Source | aldo-keto reductase family 1, member A1 (aldehyde reductase) | 6869 | 0.003 | 0.3553 | No |
| 30 | RDH10 | RDH10 Entrez, Source | retinol dehydrogenase 10 (all-trans) | 7004 | 0.002 | 0.3458 | No |
| 31 | ALDH3A1 | ALDH3A1 Entrez, Source | aldehyde dehydrogenase 3 family, memberA1 | 7461 | -0.003 | 0.3125 | No |
| 32 | HADH | HADH Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase | 7824 | -0.007 | 0.2877 | No |
| 33 | LDHA | LDHA Entrez, Source | lactate dehydrogenase A | 8185 | -0.012 | 0.2644 | No |
| 34 | PHGDH | PHGDH Entrez, Source | phosphoglycerate dehydrogenase | 8945 | -0.021 | 0.2143 | No |
| 35 | LDHC | LDHC Entrez, Source | lactate dehydrogenase C | 10601 | -0.047 | 0.1051 | No |
| 36 | SPR | SPR Entrez, Source | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) | 10749 | -0.051 | 0.1104 | No |
| 37 | CBR1 | CBR1 Entrez, Source | carbonyl reductase 1 | 10804 | -0.052 | 0.1231 | No |
| 38 | LDHB | LDHB Entrez, Source | lactate dehydrogenase B | 13053 | -0.209 | 0.0217 | No |
