Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | OXSTRESS_RPETWO_DN |
| Enrichment Score (ES) | -0.48388365 |
| Normalized Enrichment Score (NES) | -1.7569729 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.049643006 |
| FWER p-Value | 0.997 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | VCAM1 | VCAM1 Entrez, Source | vascular cell adhesion molecule 1 | 213 | 0.170 | 0.0085 | No |
| 2 | RARB | RARB Entrez, Source | retinoic acid receptor, beta | 394 | 0.136 | 0.0146 | No |
| 3 | CCR1 | CCR1 Entrez, Source | chemokine (C-C motif) receptor 1 | 410 | 0.134 | 0.0328 | No |
| 4 | ITGA7 | ITGA7 Entrez, Source | integrin, alpha 7 | 752 | 0.109 | 0.0228 | No |
| 5 | BRAF | BRAF Entrez, Source | v-raf murine sarcoma viral oncogene homolog B1 | 842 | 0.105 | 0.0313 | No |
| 6 | FGFR1 | FGFR1 Entrez, Source | fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome) | 873 | 0.104 | 0.0440 | No |
| 7 | ITGB5 | ITGB5 Entrez, Source | integrin, beta 5 | 1194 | 0.090 | 0.0329 | No |
| 8 | TCEA1 | TCEA1 Entrez, Source | transcription elongation factor A (SII), 1 | 1544 | 0.078 | 0.0179 | No |
| 9 | BMP4 | BMP4 Entrez, Source | bone morphogenetic protein 4 | 1727 | 0.074 | 0.0148 | No |
| 10 | CDH11 | CDH11 Entrez, Source | cadherin 11, type 2, OB-cadherin (osteoblast) | 1759 | 0.073 | 0.0230 | No |
| 11 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 1896 | 0.070 | 0.0228 | No |
| 12 | DFFB | DFFB Entrez, Source | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) | 2159 | 0.065 | 0.0124 | No |
| 13 | CDH2 | CDH2 Entrez, Source | cadherin 2, type 1, N-cadherin (neuronal) | 2163 | 0.065 | 0.0215 | No |
| 14 | SLC7A5 | SLC7A5 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 | 2396 | 0.060 | 0.0127 | No |
| 15 | IL3 | IL3 Entrez, Source | interleukin 3 (colony-stimulating factor, multiple) | 2935 | 0.051 | -0.0204 | No |
| 16 | TNFRSF1A | TNFRSF1A Entrez, Source | tumor necrosis factor receptor superfamily, member 1A | 2994 | 0.050 | -0.0176 | No |
| 17 | STCH | STCH Entrez, Source | stress 70 protein chaperone, microsome-associated, 60kDa | 3400 | 0.044 | -0.0417 | No |
| 18 | HGF | HGF Entrez, Source | hepatocyte growth factor (hepapoietin A; scatter factor) | 3627 | 0.041 | -0.0528 | No |
| 19 | RXRB | RXRB Entrez, Source | retinoid X receptor, beta | 3669 | 0.041 | -0.0500 | No |
| 20 | ITSN1 | ITSN1 Entrez, Source | intersectin 1 (SH3 domain protein) | 3777 | 0.040 | -0.0523 | No |
| 21 | CSDA | CSDA Entrez, Source | cold shock domain protein A | 3880 | 0.038 | -0.0545 | No |
| 22 | S100A1 | S100A1 Entrez, Source | S100 calcium binding protein A1 | 4459 | 0.030 | -0.0937 | No |
| 23 | MARK3 | MARK3 Entrez, Source | MAP/microtubule affinity-regulating kinase 3 | 4587 | 0.029 | -0.0991 | No |
| 24 | IGF1R | IGF1R Entrez, Source | insulin-like growth factor 1 receptor | 4743 | 0.027 | -0.1069 | No |
| 25 | HINT1 | HINT1 Entrez, Source | histidine triad nucleotide binding protein 1 | 4853 | 0.026 | -0.1114 | No |
| 26 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 4860 | 0.026 | -0.1082 | No |
| 27 | CDKN1C | CDKN1C Entrez, Source | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 5020 | 0.024 | -0.1168 | No |
| 28 | TSG101 | TSG101 Entrez, Source | tumor susceptibility gene 101 | 6620 | 0.006 | -0.2364 | No |
| 29 | ITGAL | ITGAL Entrez, Source | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) | 6662 | 0.006 | -0.2387 | No |
| 30 | CREB1 | CREB1 Entrez, Source | cAMP responsive element binding protein 1 | 6781 | 0.004 | -0.2470 | No |
| 31 | HGFAC | HGFAC Entrez, Source | HGF activator | 6825 | 0.004 | -0.2497 | No |
| 32 | CDC20 | CDC20 Entrez, Source | CDC20 cell division cycle 20 homolog (S. cerevisiae) | 6894 | 0.003 | -0.2543 | No |
| 33 | GPX2 | GPX2 Entrez, Source | glutathione peroxidase 2 (gastrointestinal) | 6946 | 0.003 | -0.2578 | No |
| 34 | PHB | PHB Entrez, Source | prohibitin | 7028 | 0.002 | -0.2637 | No |
| 35 | FMO1 | FMO1 Entrez, Source | flavin containing monooxygenase 1 | 7292 | -0.001 | -0.2833 | No |
| 36 | FASTK | FASTK Entrez, Source | Fas-activated serine/threonine kinase | 7355 | -0.002 | -0.2877 | No |
| 37 | RPL13A | RPL13A Entrez, Source | ribosomal protein L13a | 7679 | -0.006 | -0.3113 | No |
| 38 | CDK9 | CDK9 Entrez, Source | cyclin-dependent kinase 9 (CDC2-related kinase) | 7702 | -0.006 | -0.3121 | No |
| 39 | ARHGDIA | ARHGDIA Entrez, Source | Rho GDP dissociation inhibitor (GDI) alpha | 8158 | -0.011 | -0.3448 | No |
| 40 | GAK | GAK Entrez, Source | cyclin G associated kinase | 8374 | -0.014 | -0.3590 | No |
| 41 | TERF1 | TERF1 Entrez, Source | telomeric repeat binding factor (NIMA-interacting) 1 | 8616 | -0.017 | -0.3747 | No |
| 42 | CTNNB1 | CTNNB1 Entrez, Source | catenin (cadherin-associated protein), beta 1, 88kDa | 8921 | -0.021 | -0.3946 | No |
| 43 | PPP3CA | PPP3CA Entrez, Source | protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha) | 8966 | -0.021 | -0.3949 | No |
| 44 | CSNK1G2 | CSNK1G2 Entrez, Source | casein kinase 1, gamma 2 | 9163 | -0.024 | -0.4062 | No |
| 45 | ERBB4 | ERBB4 Entrez, Source | v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) | 9185 | -0.024 | -0.4043 | No |
| 46 | SMAD1 | SMAD1 Entrez, Source | SMAD, mothers against DPP homolog 1 (Drosophila) | 9561 | -0.030 | -0.4282 | No |
| 47 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 9613 | -0.031 | -0.4276 | No |
| 48 | ITGB4 | ITGB4 Entrez, Source | integrin, beta 4 | 9935 | -0.035 | -0.4467 | No |
| 49 | UBE2A | UBE2A Entrez, Source | ubiquitin-conjugating enzyme E2A (RAD6 homolog) | 10186 | -0.040 | -0.4599 | No |
| 50 | GTF2B | GTF2B Entrez, Source | general transcription factor IIB | 10363 | -0.043 | -0.4670 | No |
| 51 | TSC2 | TSC2 Entrez, Source | tuberous sclerosis 2 | 10588 | -0.047 | -0.4771 | Yes |
| 52 | PPP1CA | PPP1CA Entrez, Source | protein phosphatase 1, catalytic subunit, alpha isoform | 10652 | -0.048 | -0.4749 | Yes |
| 53 | BCL2L1 | BCL2L1 Entrez, Source | BCL2-like 1 | 10657 | -0.048 | -0.4683 | Yes |
| 54 | RNH1 | RNH1 Entrez, Source | ribonuclease/angiogenin inhibitor 1 | 10693 | -0.049 | -0.4638 | Yes |
| 55 | BMP1 | BMP1 Entrez, Source | bone morphogenetic protein 1 | 10783 | -0.051 | -0.4631 | Yes |
| 56 | DDR2 | DDR2 Entrez, Source | discoidin domain receptor family, member 2 | 10845 | -0.053 | -0.4602 | Yes |
| 57 | IL18 | IL18 Entrez, Source | interleukin 18 (interferon-gamma-inducing factor) | 10944 | -0.055 | -0.4596 | Yes |
| 58 | BAK1 | BAK1 Entrez, Source | BCL2-antagonist/killer 1 | 10973 | -0.055 | -0.4538 | Yes |
| 59 | YWHAH | YWHAH Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide | 11003 | -0.056 | -0.4479 | Yes |
| 60 | CDKN2B | CDKN2B Entrez, Source | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) | 11022 | -0.056 | -0.4411 | Yes |
| 61 | ACTB | ACTB Entrez, Source | actin, beta | 11264 | -0.061 | -0.4504 | Yes |
| 62 | RB1 | RB1 Entrez, Source | retinoblastoma 1 (including osteosarcoma) | 11401 | -0.065 | -0.4512 | Yes |
| 63 | BAD | BAD Entrez, Source | BCL2-antagonist of cell death | 11428 | -0.066 | -0.4437 | Yes |
| 64 | SPINT2 | SPINT2 Entrez, Source | serine peptidase inhibitor, Kunitz type, 2 | 11461 | -0.067 | -0.4364 | Yes |
| 65 | GNB2 | GNB2 Entrez, Source | guanine nucleotide binding protein (G protein), beta polypeptide 2 | 11576 | -0.071 | -0.4347 | Yes |
| 66 | CLU | CLU Entrez, Source | clusterin | 11686 | -0.075 | -0.4322 | Yes |
| 67 | SPRY2 | SPRY2 Entrez, Source | sprouty homolog 2 (Drosophila) | 11800 | -0.079 | -0.4293 | Yes |
| 68 | CDKN2D | CDKN2D Entrez, Source | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) | 11809 | -0.080 | -0.4183 | Yes |
| 69 | CAPN2 | CAPN2 Entrez, Source | calpain 2, (m/II) large subunit | 11891 | -0.083 | -0.4125 | Yes |
| 70 | LYN | LYN Entrez, Source | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 12083 | -0.091 | -0.4137 | Yes |
| 71 | DYNLL1 | DYNLL1 Entrez, Source | dynein, light chain, LC8-type 1 | 12221 | -0.098 | -0.4099 | Yes |
| 72 | QSCN6 | QSCN6 Entrez, Source | quiescin Q6 | 12235 | -0.099 | -0.3966 | Yes |
| 73 | ELK1 | ELK1 Entrez, Source | ELK1, member of ETS oncogene family | 12262 | -0.100 | -0.3841 | Yes |
| 74 | TPP1 | TPP1 Entrez, Source | tripeptidyl peptidase I | 12658 | -0.131 | -0.3950 | Yes |
| 75 | ITGA6 | ITGA6 Entrez, Source | integrin, alpha 6 | 12716 | -0.137 | -0.3795 | Yes |
| 76 | CD47 | CD47 Entrez, Source | CD47 molecule | 12956 | -0.177 | -0.3719 | Yes |
| 77 | HBEGF | HBEGF Entrez, Source | heparin-binding EGF-like growth factor | 12974 | -0.182 | -0.3469 | Yes |
| 78 | VIL2 | VIL2 Entrez, Source | villin 2 (ezrin) | 13025 | -0.196 | -0.3223 | Yes |
| 79 | ETS1 | ETS1 Entrez, Source | v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) | 13063 | -0.214 | -0.2942 | Yes |
| 80 | ZYX | ZYX Entrez, Source | zyxin | 13115 | -0.238 | -0.2636 | Yes |
| 81 | F2R | F2R Entrez, Source | coagulation factor II (thrombin) receptor | 13224 | -0.321 | -0.2255 | Yes |
| 82 | CPE | CPE Entrez, Source | carboxypeptidase E | 13284 | -0.413 | -0.1702 | Yes |
| 83 | MMP11 | MMP11 Entrez, Source | matrix metallopeptidase 11 (stromelysin 3) | 13286 | -0.422 | -0.1094 | Yes |
| 84 | MARCKSL1 | MARCKSL1 Entrez, Source | MARCKS-like 1 | 13335 | -0.786 | 0.0005 | Yes |
