Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | PROSTAGLANDIN_SYNTHESIS_REGULATION |
| Enrichment Score (ES) | -0.59754467 |
| Normalized Enrichment Score (NES) | -1.7281001 |
| Nominal p-value | 0.0073260074 |
| FDR q-value | 0.055037633 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | HSD11B1 | HSD11B1 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 1 | 318 | 0.147 | 0.0306 | No |
| 2 | PTGER1 | PTGER1 Entrez, Source | prostaglandin E receptor 1 (subtype EP1), 42kDa | 715 | 0.111 | 0.0419 | No |
| 3 | SCGB1A1 | SCGB1A1 Entrez, Source | secretoglobin, family 1A, member 1 (uteroglobin) | 759 | 0.109 | 0.0788 | No |
| 4 | PTGS2 | PTGS2 Entrez, Source | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 886 | 0.103 | 0.1076 | No |
| 5 | PRL | PRL Entrez, Source | prolactin | 1687 | 0.075 | 0.0751 | No |
| 6 | PTGIS | PTGIS Entrez, Source | prostaglandin I2 (prostacyclin) synthase | 2515 | 0.058 | 0.0345 | No |
| 7 | PTGS1 | PTGS1 Entrez, Source | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) | 3007 | 0.050 | 0.0161 | No |
| 8 | HPGD | HPGD Entrez, Source | hydroxyprostaglandin dehydrogenase 15-(NAD) | 3915 | 0.038 | -0.0381 | No |
| 9 | PLA2G4A | PLA2G4A Entrez, Source | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 4307 | 0.033 | -0.0554 | No |
| 10 | TBXAS1 | TBXAS1 Entrez, Source | thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A) | 4744 | 0.027 | -0.0781 | No |
| 11 | CYP11A1 | CYP11A1 Entrez, Source | cytochrome P450, family 11, subfamily A, polypeptide 1 | 5484 | 0.019 | -0.1268 | No |
| 12 | HSD11B2 | HSD11B2 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 2 | 5960 | 0.013 | -0.1576 | No |
| 13 | PTGER2 | PTGER2 Entrez, Source | prostaglandin E receptor 2 (subtype EP2), 53kDa | 6027 | 0.013 | -0.1579 | No |
| 14 | EDNRA | EDNRA Entrez, Source | endothelin receptor type A | 6222 | 0.011 | -0.1685 | No |
| 15 | PTGDS | PTGDS Entrez, Source | prostaglandin D2 synthase 21kDa (brain) | 6985 | 0.002 | -0.2250 | No |
| 16 | EDNRB | EDNRB Entrez, Source | endothelin receptor type B | 7246 | -0.001 | -0.2442 | No |
| 17 | PTGFR | PTGFR Entrez, Source | prostaglandin F receptor (FP) | 8805 | -0.019 | -0.3541 | No |
| 18 | ANXA6 | ANXA6 Entrez, Source | annexin A6 | 9885 | -0.035 | -0.4223 | No |
| 19 | ANXA8 | ANXA8 Entrez, Source | annexin A8 | 10533 | -0.046 | -0.4540 | No |
| 20 | ANXA4 | ANXA4 Entrez, Source | annexin A4 | 12446 | -0.114 | -0.5554 | Yes |
| 21 | PTGER4 | PTGER4 Entrez, Source | prostaglandin E receptor 4 (subtype EP4) | 12537 | -0.120 | -0.5176 | Yes |
| 22 | ANXA2 | ANXA2 Entrez, Source | annexin A2 | 12686 | -0.133 | -0.4794 | Yes |
| 23 | ANXA5 | ANXA5 Entrez, Source | annexin A5 | 12886 | -0.162 | -0.4344 | Yes |
| 24 | EDN1 | EDN1 Entrez, Source | endothelin 1 | 13031 | -0.199 | -0.3714 | Yes |
| 25 | ANXA3 | ANXA3 Entrez, Source | annexin A3 | 13112 | -0.236 | -0.2899 | Yes |
| 26 | S100A6 | S100A6 Entrez, Source | S100 calcium binding protein A6 | 13234 | -0.331 | -0.1764 | Yes |
| 27 | ANXA1 | ANXA1 Entrez, Source | annexin A1 | 13312 | -0.498 | 0.0023 | Yes |
