Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | PTDINSPATHWAY |
| Enrichment Score (ES) | -0.6494494 |
| Normalized Enrichment Score (NES) | -1.7091781 |
| Nominal p-value | 0.007490637 |
| FDR q-value | 0.06313605 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PRKCE | PRKCE Entrez, Source | protein kinase C, epsilon | 2008 | 0.068 | -0.1006 | No |
| 2 | GRASP | GRASP Entrez, Source | GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein | 3065 | 0.049 | -0.1436 | No |
| 3 | RAB5A | RAB5A Entrez, Source | RAB5A, member RAS oncogene family | 4533 | 0.030 | -0.2318 | No |
| 4 | RPS6KB1 | RPS6KB1 Entrez, Source | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | 4614 | 0.028 | -0.2168 | No |
| 5 | PDPK1 | PDPK1 Entrez, Source | 3-phosphoinositide dependent protein kinase-1 | 5563 | 0.018 | -0.2750 | No |
| 6 | GSK3A | GSK3A Entrez, Source | glycogen synthase kinase 3 alpha | 5648 | 0.017 | -0.2690 | No |
| 7 | PRKCZ | PRKCZ Entrez, Source | protein kinase C, zeta | 6220 | 0.011 | -0.3040 | No |
| 8 | ARF1 | ARF1 Entrez, Source | ADP-ribosylation factor 1 | 6593 | 0.007 | -0.3271 | No |
| 9 | AP2M1 | AP2M1 Entrez, Source | adaptor-related protein complex 2, mu 1 subunit | 6739 | 0.005 | -0.3343 | No |
| 10 | RAC1 | RAC1 Entrez, Source | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 10939 | -0.055 | -0.6092 | Yes |
| 11 | PFKM | PFKM Entrez, Source | phosphofructokinase, muscle | 11295 | -0.062 | -0.5899 | Yes |
| 12 | BAD | BAD Entrez, Source | BCL2-antagonist of cell death | 11428 | -0.066 | -0.5511 | Yes |
| 13 | GSK3B | GSK3B Entrez, Source | glycogen synthase kinase 3 beta | 11670 | -0.074 | -0.5143 | Yes |
| 14 | PLCG1 | PLCG1 Entrez, Source | phospholipase C, gamma 1 | 11883 | -0.083 | -0.4693 | Yes |
| 15 | AKT1 | AKT1 Entrez, Source | v-akt murine thymoma viral oncogene homolog 1 | 11925 | -0.084 | -0.4102 | Yes |
| 16 | LYN | LYN Entrez, Source | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 12083 | -0.091 | -0.3549 | Yes |
| 17 | PFKL | PFKL Entrez, Source | phosphofructokinase, liver | 12126 | -0.093 | -0.2895 | Yes |
| 18 | PFKP | PFKP Entrez, Source | phosphofructokinase, platelet | 13318 | -0.516 | 0.0018 | Yes |
