Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | RASPATHWAY |
| Enrichment Score (ES) | -0.65730673 |
| Normalized Enrichment Score (NES) | -1.7845454 |
| Nominal p-value | 0.007352941 |
| FDR q-value | 0.04499912 |
| FWER p-Value | 0.985 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | RAF1 | RAF1 Entrez, Source | v-raf-1 murine leukemia viral oncogene homolog 1 | 2284 | 0.062 | -0.1227 | No |
| 2 | PIK3R1 | PIK3R1 Entrez, Source | phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha) | 2668 | 0.056 | -0.1078 | No |
| 3 | CASP9 | CASP9 Entrez, Source | caspase 9, apoptosis-related cysteine peptidase | 5394 | 0.019 | -0.2972 | No |
| 4 | MAP2K1 | MAP2K1 Entrez, Source | mitogen-activated protein kinase kinase 1 | 8219 | -0.012 | -0.4998 | No |
| 5 | HRAS | HRAS Entrez, Source | v-Ha-ras Harvey rat sarcoma viral oncogene homolog | 9267 | -0.025 | -0.5585 | No |
| 6 | RHOA | RHOA Entrez, Source | ras homolog gene family, member A | 10584 | -0.047 | -0.6209 | Yes |
| 7 | BCL2L1 | BCL2L1 Entrez, Source | BCL2-like 1 | 10657 | -0.048 | -0.5887 | Yes |
| 8 | CDC42 | CDC42 Entrez, Source | cell division cycle 42 (GTP binding protein, 25kDa) | 10703 | -0.049 | -0.5535 | Yes |
| 9 | RALGDS | RALGDS Entrez, Source | ral guanine nucleotide dissociation stimulator | 10901 | -0.054 | -0.5263 | Yes |
| 10 | RAC1 | RAC1 Entrez, Source | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 10939 | -0.055 | -0.4865 | Yes |
| 11 | RALA | RALA Entrez, Source | v-ral simian leukemia viral oncogene homolog A (ras related) | 11027 | -0.056 | -0.4490 | Yes |
| 12 | RELA | RELA Entrez, Source | v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian) | 11138 | -0.059 | -0.4113 | Yes |
| 13 | RALBP1 | RALBP1 Entrez, Source | ralA binding protein 1 | 11203 | -0.060 | -0.3690 | Yes |
| 14 | BAD | BAD Entrez, Source | BCL2-antagonist of cell death | 11428 | -0.066 | -0.3343 | Yes |
| 15 | NFKB1 | NFKB1 Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) | 11510 | -0.069 | -0.2868 | Yes |
| 16 | H2AFX | H2AFX Entrez, Source | H2A histone family, member X | 11841 | -0.081 | -0.2485 | Yes |
| 17 | AKT1 | AKT1 Entrez, Source | v-akt murine thymoma viral oncogene homolog 1 | 11925 | -0.084 | -0.1890 | Yes |
| 18 | ELK1 | ELK1 Entrez, Source | ELK1, member of ETS oncogene family | 12262 | -0.100 | -0.1358 | Yes |
| 19 | MAPK3 | MAPK3 Entrez, Source | mitogen-activated protein kinase 3 | 12674 | -0.132 | -0.0639 | Yes |
| 20 | PIK3CA | PIK3CA Entrez, Source | phosphoinositide-3-kinase, catalytic, alpha polypeptide | 12788 | -0.146 | 0.0416 | Yes |
