Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | REGULATION_OF_NEUROTRANSMITTER_LEVELS |
| Enrichment Score (ES) | 0.5052176 |
| Normalized Enrichment Score (NES) | 1.471108 |
| Nominal p-value | 0.05652174 |
| FDR q-value | 0.1624857 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GCH1 | GCH1 Entrez, Source | GTP cyclohydrolase 1 (dopa-responsive dystonia) | 441 | 0.131 | 0.1039 | Yes |
| 2 | SEPT5 | SEPT5 Entrez, Source | septin 5 | 645 | 0.116 | 0.2100 | Yes |
| 3 | SYN3 | SYN3 Entrez, Source | synapsin III | 1649 | 0.076 | 0.2141 | Yes |
| 4 | RIMS1 | RIMS1 Entrez, Source | regulating synaptic membrane exocytosis 1 | 1884 | 0.070 | 0.2701 | Yes |
| 5 | SLC5A7 | SLC5A7 Entrez, Source | solute carrier family 5 (choline transporter), member 7 | 1922 | 0.070 | 0.3402 | Yes |
| 6 | KCNMB4 | KCNMB4 Entrez, Source | potassium large conductance calcium-activated channel, subfamily M, beta member 4 | 2759 | 0.054 | 0.3342 | Yes |
| 7 | GCHFR | GCHFR Entrez, Source | GTP cyclohydrolase I feedback regulator | 3033 | 0.050 | 0.3656 | Yes |
| 8 | RAB3A | RAB3A Entrez, Source | RAB3A, member RAS oncogene family | 3041 | 0.049 | 0.4168 | Yes |
| 9 | NLGN1 | NLGN1 Entrez, Source | neuroligin 1 | 3061 | 0.049 | 0.4669 | Yes |
| 10 | GRM4 | GRM4 Entrez, Source | glutamate receptor, metabotropic 4 | 3208 | 0.047 | 0.5052 | Yes |
| 11 | SLC6A4 | SLC6A4 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 | 3952 | 0.037 | 0.4883 | No |
| 12 | SLC1A3 | SLC1A3 Entrez, Source | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | 4742 | 0.027 | 0.4574 | No |
| 13 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 5353 | 0.020 | 0.4323 | No |
| 14 | SYT1 | SYT1 Entrez, Source | synaptotagmin I | 5561 | 0.018 | 0.4352 | No |
| 15 | COLQ | COLQ Entrez, Source | collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase | 6022 | 0.013 | 0.4138 | No |
| 16 | CARTPT | CARTPT Entrez, Source | CART prepropeptide | 7384 | -0.002 | 0.3141 | No |
| 17 | HRH3 | HRH3 Entrez, Source | histamine receptor H3 | 7593 | -0.005 | 0.3035 | No |
| 18 | GDNF | GDNF Entrez, Source | glial cell derived neurotrophic factor | 8466 | -0.015 | 0.2539 | No |
| 19 | ALDH9A1 | ALDH9A1 Entrez, Source | aldehyde dehydrogenase 9 family, member A1 | 9309 | -0.026 | 0.2179 | No |
| 20 | HPRT1 | HPRT1 Entrez, Source | hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome) | 11843 | -0.081 | 0.1125 | No |
