Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | ROS_MOUSE_AORTA_DN |
| Enrichment Score (ES) | -0.52052784 |
| Normalized Enrichment Score (NES) | -1.7589822 |
| Nominal p-value | 0.0016666667 |
| FDR q-value | 0.04949051 |
| FWER p-Value | 0.997 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ARG1 | ARG1 Entrez, Source | arginase, liver | 117 | 0.209 | 0.0256 | No |
| 2 | CD14 | CD14 Entrez, Source | CD14 molecule | 253 | 0.159 | 0.0416 | No |
| 3 | ATF3 | ATF3 Entrez, Source | activating transcription factor 3 | 329 | 0.145 | 0.0598 | No |
| 4 | HDC | HDC Entrez, Source | histidine decarboxylase | 383 | 0.138 | 0.0786 | No |
| 5 | LYZ | LYZ Entrez, Source | lysozyme (renal amyloidosis) | 440 | 0.131 | 0.0959 | No |
| 6 | BHLHB2 | BHLHB2 Entrez, Source | basic helix-loop-helix domain containing, class B, 2 | 766 | 0.108 | 0.0893 | No |
| 7 | PON1 | PON1 Entrez, Source | paraoxonase 1 | 922 | 0.101 | 0.0943 | No |
| 8 | ARL6IP2 | ARL6IP2 Entrez, Source | ADP-ribosylation factor-like 6 interacting protein 2 | 1087 | 0.094 | 0.0974 | No |
| 9 | IL1B | IL1B Entrez, Source | interleukin 1, beta | 1495 | 0.079 | 0.0799 | No |
| 10 | ALDH1A1 | ALDH1A1 Entrez, Source | aldehyde dehydrogenase 1 family, member A1 | 1653 | 0.076 | 0.0805 | No |
| 11 | CTSS | CTSS Entrez, Source | cathepsin S | 1728 | 0.074 | 0.0871 | No |
| 12 | PTGIS | PTGIS Entrez, Source | prostaglandin I2 (prostacyclin) synthase | 2515 | 0.058 | 0.0375 | No |
| 13 | CD9 | CD9 Entrez, Source | CD9 molecule | 2527 | 0.058 | 0.0462 | No |
| 14 | MGP | MGP Entrez, Source | matrix Gla protein | 2580 | 0.057 | 0.0517 | No |
| 15 | IGFBP5 | IGFBP5 Entrez, Source | insulin-like growth factor binding protein 5 | 2629 | 0.056 | 0.0574 | No |
| 16 | MYH11 | MYH11 Entrez, Source | myosin, heavy chain 11, smooth muscle | 2696 | 0.055 | 0.0616 | No |
| 17 | S100A9 | S100A9 Entrez, Source | S100 calcium binding protein A9 | 2964 | 0.051 | 0.0498 | No |
| 18 | SERPING1 | SERPING1 Entrez, Source | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary) | 3232 | 0.047 | 0.0374 | No |
| 19 | SLC25A1 | SLC25A1 Entrez, Source | solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 | 3477 | 0.043 | 0.0262 | No |
| 20 | CD5L | CD5L Entrez, Source | CD5 molecule-like | 4008 | 0.036 | -0.0077 | No |
| 21 | ENAH | ENAH Entrez, Source | enabled homolog (Drosophila) | 4261 | 0.033 | -0.0213 | No |
| 22 | RBP1 | RBP1 Entrez, Source | retinol binding protein 1, cellular | 4518 | 0.030 | -0.0356 | No |
| 23 | SYN1 | SYN1 Entrez, Source | synapsin I | 4992 | 0.024 | -0.0672 | No |
| 24 | MMP9 | MMP9 Entrez, Source | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 5075 | 0.023 | -0.0696 | No |
| 25 | RPL18 | RPL18 Entrez, Source | ribosomal protein L18 | 6291 | 0.010 | -0.1595 | No |
| 26 | EXOSC7 | EXOSC7 Entrez, Source | exosome component 7 | 6360 | 0.009 | -0.1631 | No |
| 27 | PMP22 | PMP22 Entrez, Source | peripheral myelin protein 22 | 6574 | 0.007 | -0.1780 | No |
| 28 | BGN | BGN Entrez, Source | biglycan | 7068 | 0.001 | -0.2149 | No |
| 29 | RPS5 | RPS5 Entrez, Source | ribosomal protein S5 | 7352 | -0.002 | -0.2359 | No |
| 30 | EMP3 | EMP3 Entrez, Source | epithelial membrane protein 3 | 7711 | -0.006 | -0.2618 | No |
| 31 | ELN | ELN Entrez, Source | elastin (supravalvular aortic stenosis, Williams-Beuren syndrome) | 7755 | -0.007 | -0.2640 | No |
| 32 | ALAS2 | ALAS2 Entrez, Source | aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia) | 8816 | -0.019 | -0.3406 | No |
| 33 | SFRP2 | SFRP2 Entrez, Source | secreted frizzled-related protein 2 | 9638 | -0.031 | -0.3973 | No |
| 34 | GADD45B | GADD45B Entrez, Source | growth arrest and DNA-damage-inducible, beta | 10614 | -0.047 | -0.4629 | No |
| 35 | BTG3 | BTG3 Entrez, Source | BTG family, member 3 | 11098 | -0.058 | -0.4897 | No |
| 36 | HIF1A | HIF1A Entrez, Source | hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 11170 | -0.060 | -0.4852 | No |
| 37 | ACTB | ACTB Entrez, Source | actin, beta | 11264 | -0.061 | -0.4821 | No |
| 38 | PTPN23 | PTPN23 Entrez, Source | protein tyrosine phosphatase, non-receptor type 23 | 11570 | -0.071 | -0.4934 | No |
| 39 | CLU | CLU Entrez, Source | clusterin | 11686 | -0.075 | -0.4897 | No |
| 40 | ARG2 | ARG2 Entrez, Source | arginase, type II | 12097 | -0.091 | -0.5055 | Yes |
| 41 | CAPZB | CAPZB Entrez, Source | capping protein (actin filament) muscle Z-line, beta | 12275 | -0.102 | -0.5021 | Yes |
| 42 | IL1R2 | IL1R2 Entrez, Source | interleukin 1 receptor, type II | 12286 | -0.103 | -0.4859 | Yes |
| 43 | DSTN | DSTN Entrez, Source | destrin (actin depolymerizing factor) | 12710 | -0.136 | -0.4954 | Yes |
| 44 | GNAI2 | GNAI2 Entrez, Source | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | 12765 | -0.143 | -0.4758 | Yes |
| 45 | CSRP1 | CSRP1 Entrez, Source | cysteine and glycine-rich protein 1 | 12832 | -0.153 | -0.4556 | Yes |
| 46 | CYBA | CYBA Entrez, Source | cytochrome b-245, alpha polypeptide | 12938 | -0.173 | -0.4349 | Yes |
| 47 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 12980 | -0.185 | -0.4076 | Yes |
| 48 | ANXA3 | ANXA3 Entrez, Source | annexin A3 | 13112 | -0.236 | -0.3785 | Yes |
| 49 | RCN2 | RCN2 Entrez, Source | reticulocalbin 2, EF-hand calcium binding domain | 13116 | -0.238 | -0.3395 | Yes |
| 50 | GPX3 | GPX3 Entrez, Source | glutathione peroxidase 3 (plasma) | 13121 | -0.240 | -0.3003 | Yes |
| 51 | FXYD5 | FXYD5 Entrez, Source | FXYD domain containing ion transport regulator 5 | 13131 | -0.248 | -0.2602 | Yes |
| 52 | S100A6 | S100A6 Entrez, Source | S100 calcium binding protein A6 | 13234 | -0.331 | -0.2133 | Yes |
| 53 | LCP1 | LCP1 Entrez, Source | lymphocyte cytosolic protein 1 (L-plastin) | 13280 | -0.405 | -0.1500 | Yes |
| 54 | CPE | CPE Entrez, Source | carboxypeptidase E | 13284 | -0.413 | -0.0822 | Yes |
| 55 | RGS2 | RGS2 Entrez, Source | regulator of G-protein signalling 2, 24kDa | 13320 | -0.525 | 0.0017 | Yes |
