Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | SANA_TNFA_ENDOTHELIAL_UP |
| Enrichment Score (ES) | -0.5752774 |
| Normalized Enrichment Score (NES) | -1.8499233 |
| Nominal p-value | 0.0050847456 |
| FDR q-value | 0.03321525 |
| FWER p-Value | 0.869 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | VCAM1 | VCAM1 Entrez, Source | vascular cell adhesion molecule 1 | 213 | 0.170 | 0.0175 | No |
| 2 | MMP3 | MMP3 Entrez, Source | matrix metallopeptidase 3 (stromelysin 1, progelatinase) | 351 | 0.142 | 0.0352 | No |
| 3 | SLC7A2 | SLC7A2 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 494 | 0.125 | 0.0492 | No |
| 4 | IFIT1 | IFIT1 Entrez, Source | interferon-induced protein with tetratricopeptide repeats 1 | 750 | 0.109 | 0.0515 | No |
| 5 | CASP1 | CASP1 Entrez, Source | caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) | 809 | 0.106 | 0.0682 | No |
| 6 | UBD | UBD Entrez, Source | ubiquitin D | 1268 | 0.087 | 0.0509 | No |
| 7 | RHOB | RHOB Entrez, Source | ras homolog gene family, member B | 1840 | 0.071 | 0.0221 | No |
| 8 | MX1 | MX1 Entrez, Source | myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) | 2175 | 0.064 | 0.0096 | No |
| 9 | CTHRC1 | CTHRC1 Entrez, Source | collagen triple helix repeat containing 1 | 2305 | 0.062 | 0.0121 | No |
| 10 | CXCR7 | CXCR7 Entrez, Source | chemokine (C-X-C motif) receptor 7 | 2536 | 0.058 | 0.0063 | No |
| 11 | SLC15A3 | SLC15A3 Entrez, Source | solute carrier family 15, member 3 | 2891 | 0.052 | -0.0101 | No |
| 12 | OAS1 | OAS1 Entrez, Source | 2',5'-oligoadenylate synthetase 1, 40/46kDa | 3313 | 0.046 | -0.0328 | No |
| 13 | SOD2 | SOD2 Entrez, Source | superoxide dismutase 2, mitochondrial | 3354 | 0.045 | -0.0269 | No |
| 14 | LGALS9 | LGALS9 Entrez, Source | lectin, galactoside-binding, soluble, 9 (galectin 9) | 4715 | 0.027 | -0.1238 | No |
| 15 | CCL11 | CCL11 Entrez, Source | chemokine (C-C motif) ligand 11 | 4869 | 0.026 | -0.1302 | No |
| 16 | CSF1 | CSF1 Entrez, Source | colony stimulating factor 1 (macrophage) | 5308 | 0.020 | -0.1591 | No |
| 17 | FTH1 | FTH1 Entrez, Source | ferritin, heavy polypeptide 1 | 6227 | 0.011 | -0.2261 | No |
| 18 | C1QTNF1 | C1QTNF1 Entrez, Source | C1q and tumor necrosis factor related protein 1 | 6358 | 0.009 | -0.2341 | No |
| 19 | TLR2 | TLR2 Entrez, Source | toll-like receptor 2 | 6981 | 0.002 | -0.2804 | No |
| 20 | BPGM | BPGM Entrez, Source | 2,3-bisphosphoglycerate mutase | 7240 | -0.001 | -0.2997 | No |
| 21 | INHBA | INHBA Entrez, Source | inhibin, beta A (activin A, activin AB alpha polypeptide) | 7648 | -0.005 | -0.3293 | No |
| 22 | ICAM1 | ICAM1 Entrez, Source | intercellular adhesion molecule 1 (CD54), human rhinovirus receptor | 8686 | -0.018 | -0.4037 | No |
| 23 | DHRS8 | DHRS8 Entrez, Source | dehydrogenase/reductase (SDR family) member 8 | 8808 | -0.019 | -0.4090 | No |
| 24 | BST2 | BST2 Entrez, Source | bone marrow stromal cell antigen 2 | 9025 | -0.022 | -0.4209 | No |
| 25 | DNAJA1 | DNAJA1 Entrez, Source | DnaJ (Hsp40) homolog, subfamily A, member 1 | 9406 | -0.028 | -0.4440 | No |
| 26 | MX2 | MX2 Entrez, Source | myxovirus (influenza virus) resistance 2 (mouse) | 9715 | -0.032 | -0.4608 | No |
| 27 | MMP10 | MMP10 Entrez, Source | matrix metallopeptidase 10 (stromelysin 2) | 9894 | -0.035 | -0.4673 | No |
| 28 | NFKBIA | NFKBIA Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 10388 | -0.043 | -0.4958 | No |
| 29 | SMAD3 | SMAD3 Entrez, Source | SMAD, mothers against DPP homolog 3 (Drosophila) | 11131 | -0.059 | -0.5400 | No |
| 30 | CCL7 | CCL7 Entrez, Source | chemokine (C-C motif) ligand 7 | 11391 | -0.065 | -0.5467 | No |
| 31 | CXCL10 | CXCL10 Entrez, Source | chemokine (C-X-C motif) ligand 10 | 11740 | -0.077 | -0.5577 | No |
| 32 | CX3CL1 | CX3CL1 Entrez, Source | chemokine (C-X3-C motif) ligand 1 | 11975 | -0.086 | -0.5583 | Yes |
| 33 | TAPBP | TAPBP Entrez, Source | TAP binding protein (tapasin) | 12170 | -0.095 | -0.5542 | Yes |
| 34 | OXR1 | OXR1 Entrez, Source | oxidation resistance 1 | 12320 | -0.105 | -0.5447 | Yes |
| 35 | RIPK2 | RIPK2 Entrez, Source | receptor-interacting serine-threonine kinase 2 | 12565 | -0.122 | -0.5389 | Yes |
| 36 | BIRC3 | BIRC3 Entrez, Source | baculoviral IAP repeat-containing 3 | 12722 | -0.137 | -0.5235 | Yes |
| 37 | PLA1A | PLA1A Entrez, Source | phospholipase A1 member A | 13005 | -0.190 | -0.5073 | Yes |
| 38 | CXCL11 | CXCL11 Entrez, Source | chemokine (C-X-C motif) ligand 11 | 13092 | -0.227 | -0.4689 | Yes |
| 39 | LGALS3BP | LGALS3BP Entrez, Source | lectin, galactoside-binding, soluble, 3 binding protein | 13202 | -0.293 | -0.4192 | Yes |
| 40 | LAMB3 | LAMB3 Entrez, Source | laminin, beta 3 | 13233 | -0.329 | -0.3566 | Yes |
| 41 | CXCL2 | CXCL2 Entrez, Source | chemokine (C-X-C motif) ligand 2 | 13254 | -0.355 | -0.2880 | Yes |
| 42 | CCL20 | CCL20 Entrez, Source | chemokine (C-C motif) ligand 20 | 13267 | -0.380 | -0.2139 | Yes |
| 43 | SERPINE1 | SERPINE1 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 13308 | -0.484 | -0.1213 | Yes |
| 44 | CCL2 | CCL2 Entrez, Source | chemokine (C-C motif) ligand 2 | 13326 | -0.627 | 0.0012 | Yes |
