Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | SERUM_FIBROBLAST_CELLCYCLE |
| Enrichment Score (ES) | -0.6842631 |
| Normalized Enrichment Score (NES) | -2.258491 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0011516934 |
| FWER p-Value | 0.0030 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | DHFR | DHFR Entrez, Source | dihydrofolate reductase | 883 | 0.103 | -0.0463 | No |
| 2 | USP1 | USP1 Entrez, Source | ubiquitin specific peptidase 1 | 909 | 0.102 | -0.0284 | No |
| 3 | SPAG5 | SPAG5 Entrez, Source | sperm associated antigen 5 | 3211 | 0.047 | -0.1924 | No |
| 4 | MAPK13 | MAPK13 Entrez, Source | mitogen-activated protein kinase 13 | 3290 | 0.046 | -0.1893 | No |
| 5 | RANGAP1 | RANGAP1 Entrez, Source | Ran GTPase activating protein 1 | 3631 | 0.041 | -0.2069 | No |
| 6 | SMC4 | SMC4 Entrez, Source | structural maintenance of chromosomes 4 | 4217 | 0.034 | -0.2444 | No |
| 7 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 4258 | 0.033 | -0.2410 | No |
| 8 | CDKN3 | CDKN3 Entrez, Source | cyclin-dependent kinase inhibitor 3 (CDK2-associated dual specificity phosphatase) | 4303 | 0.033 | -0.2379 | No |
| 9 | CCNF | CCNF Entrez, Source | cyclin F | 4467 | 0.030 | -0.2443 | No |
| 10 | CIITA | CIITA Entrez, Source | class II, major histocompatibility complex, transactivator | 4792 | 0.026 | -0.2635 | No |
| 11 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 4860 | 0.026 | -0.2636 | No |
| 12 | LYAR | LYAR Entrez, Source | - | 5575 | 0.017 | -0.3140 | No |
| 13 | AMD1 | AMD1 Entrez, Source | adenosylmethionine decarboxylase 1 | 5628 | 0.017 | -0.3146 | No |
| 14 | ANP32E | ANP32E Entrez, Source | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 6197 | 0.011 | -0.3552 | No |
| 15 | ABCC5 | ABCC5 Entrez, Source | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 6552 | 0.007 | -0.3805 | No |
| 16 | PLK1 | PLK1 Entrez, Source | polo-like kinase 1 (Drosophila) | 7563 | -0.004 | -0.4556 | No |
| 17 | BARD1 | BARD1 Entrez, Source | BRCA1 associated RING domain 1 | 8325 | -0.013 | -0.5103 | No |
| 18 | FEN1 | FEN1 Entrez, Source | flap structure-specific endonuclease 1 | 8375 | -0.014 | -0.5113 | No |
| 19 | CDCA1 | CDCA1 Entrez, Source | cell division cycle associated 1 | 8728 | -0.018 | -0.5342 | No |
| 20 | RFC2 | RFC2 Entrez, Source | replication factor C (activator 1) 2, 40kDa | 8785 | -0.019 | -0.5347 | No |
| 21 | TUBB2C | TUBB2C Entrez, Source | tubulin, beta 2C | 9095 | -0.023 | -0.5535 | No |
| 22 | FOXM1 | FOXM1 Entrez, Source | forkhead box M1 | 9257 | -0.025 | -0.5607 | No |
| 23 | FBXL20 | FBXL20 Entrez, Source | F-box and leucine-rich repeat protein 20 | 9305 | -0.026 | -0.5592 | No |
| 24 | AURKA | AURKA Entrez, Source | aurora kinase A | 9722 | -0.032 | -0.5842 | No |
| 25 | TOP2A | TOP2A Entrez, Source | topoisomerase (DNA) II alpha 170kDa | 10131 | -0.039 | -0.6073 | No |
| 26 | PTTG1 | PTTG1 Entrez, Source | pituitary tumor-transforming 1 | 10625 | -0.047 | -0.6352 | No |
| 27 | PRIM2A | PRIM2A Entrez, Source | primase, polypeptide 2A, 58kDa | 10779 | -0.051 | -0.6368 | No |
| 28 | ADAMTS1 | ADAMTS1 Entrez, Source | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 10942 | -0.055 | -0.6383 | No |
| 29 | YWHAH | YWHAH Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide | 11003 | -0.056 | -0.6320 | No |
| 30 | SDC1 | SDC1 Entrez, Source | syndecan 1 | 11699 | -0.075 | -0.6696 | Yes |
| 31 | H2AFX | H2AFX Entrez, Source | H2A histone family, member X | 11841 | -0.081 | -0.6645 | Yes |
| 32 | HMMR | HMMR Entrez, Source | hyaluronan-mediated motility receptor (RHAMM) | 11850 | -0.081 | -0.6493 | Yes |
| 33 | CDCA7 | CDCA7 Entrez, Source | cell division cycle associated 7 | 11981 | -0.086 | -0.6424 | Yes |
| 34 | CASP3 | CASP3 Entrez, Source | caspase 3, apoptosis-related cysteine peptidase | 12003 | -0.087 | -0.6271 | Yes |
| 35 | PRIM1 | PRIM1 Entrez, Source | primase, polypeptide 1, 49kDa | 12091 | -0.091 | -0.6159 | Yes |
| 36 | DONSON | DONSON Entrez, Source | downstream neighbor of SON | 12119 | -0.092 | -0.6000 | Yes |
| 37 | KIFC1 | KIFC1 Entrez, Source | kinesin family member C1 | 12256 | -0.100 | -0.5908 | Yes |
| 38 | TUBB | TUBB Entrez, Source | tubulin, beta | 12364 | -0.108 | -0.5778 | Yes |
| 39 | CCNB2 | CCNB2 Entrez, Source | cyclin B2 | 12396 | -0.111 | -0.5586 | Yes |
| 40 | HN1 | HN1 Entrez, Source | hematological and neurological expressed 1 | 12571 | -0.123 | -0.5478 | Yes |
| 41 | MET | MET Entrez, Source | met proto-oncogene (hepatocyte growth factor receptor) | 12631 | -0.128 | -0.5274 | Yes |
| 42 | CDCA8 | CDCA8 Entrez, Source | cell division cycle associated 8 | 12643 | -0.129 | -0.5031 | Yes |
| 43 | TYMS | TYMS Entrez, Source | thymidylate synthetase | 12749 | -0.141 | -0.4837 | Yes |
| 44 | TRIP13 | TRIP13 Entrez, Source | thyroid hormone receptor interactor 13 | 12798 | -0.147 | -0.4587 | Yes |
| 45 | TACC3 | TACC3 Entrez, Source | transforming, acidic coiled-coil containing protein 3 | 12826 | -0.152 | -0.4312 | Yes |
| 46 | PAQR4 | PAQR4 Entrez, Source | progestin and adipoQ receptor family member IV | 12860 | -0.158 | -0.4030 | Yes |
| 47 | WSB1 | WSB1 Entrez, Source | WD repeat and SOCS box-containing 1 | 13006 | -0.190 | -0.3770 | Yes |
| 48 | ANKRD10 | ANKRD10 Entrez, Source | ankyrin repeat domain 10 | 13034 | -0.200 | -0.3402 | Yes |
| 49 | LMNB1 | LMNB1 Entrez, Source | lamin B1 | 13104 | -0.234 | -0.2999 | Yes |
| 50 | TIMP1 | TIMP1 Entrez, Source | TIMP metallopeptidase inhibitor 1 | 13187 | -0.286 | -0.2506 | Yes |
| 51 | CCNA2 | CCNA2 Entrez, Source | cyclin A2 | 13257 | -0.367 | -0.1845 | Yes |
| 52 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13301 | -0.469 | -0.0965 | Yes |
| 53 | KIAA0101 | KIAA0101 Entrez, Source | KIAA0101 | 13316 | -0.512 | 0.0020 | Yes |
