Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | STRIATED_MUSCLE_CONTRACTION |
| Enrichment Score (ES) | -0.62188494 |
| Normalized Enrichment Score (NES) | -1.7321714 |
| Nominal p-value | 0.0073664826 |
| FDR q-value | 0.0541701 |
| FWER p-Value | 0.999 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | MYH6 /// MYH7 | 393 | 0.136 | 0.0092 | No | ||
| 2 | TNNI3 | TNNI3 Entrez, Source | troponin I type 3 (cardiac) | 402 | 0.135 | 0.0470 | No |
| 3 | TNNT1 | TNNT1 Entrez, Source | troponin T type 1 (skeletal, slow) | 714 | 0.111 | 0.0552 | No |
| 4 | TTN | TTN Entrez, Source | titin | 1695 | 0.074 | 0.0027 | No |
| 5 | TNNI1 | TNNI1 Entrez, Source | troponin I type 1 (skeletal, slow) | 1767 | 0.073 | 0.0181 | No |
| 6 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 1934 | 0.070 | 0.0253 | No |
| 7 | MYOM1 | MYOM1 Entrez, Source | myomesin 1 (skelemin) 185kDa | 2024 | 0.067 | 0.0378 | No |
| 8 | MYH6 | MYH6 Entrez, Source | myosin, heavy chain 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1) | 2066 | 0.067 | 0.0536 | No |
| 9 | MYBPC1 | MYBPC1 Entrez, Source | myosin binding protein C, slow type | 2269 | 0.063 | 0.0563 | No |
| 10 | TNNT3 | TNNT3 Entrez, Source | troponin T type 3 (skeletal, fast) | 2298 | 0.062 | 0.0718 | No |
| 11 | MYH3 | MYH3 Entrez, Source | myosin, heavy chain 3, skeletal muscle, embryonic | 2301 | 0.062 | 0.0893 | No |
| 12 | TNNI2 | TNNI2 Entrez, Source | troponin I type 2 (skeletal, fast) | 2692 | 0.055 | 0.0757 | No |
| 13 | MYL2 | MYL2 Entrez, Source | myosin, light chain 2, regulatory, cardiac, slow | 2705 | 0.055 | 0.0904 | No |
| 14 | MYL3 | MYL3 Entrez, Source | myosin, light chain 3, alkali; ventricular, skeletal, slow | 5248 | 0.021 | -0.0945 | No |
| 15 | TNNT2 | TNNT2 Entrez, Source | troponin T type 2 (cardiac) | 5334 | 0.020 | -0.0952 | No |
| 16 | DES | DES Entrez, Source | desmin | 8619 | -0.017 | -0.3369 | No |
| 17 | MYH8 | MYH8 Entrez, Source | myosin, heavy chain 8, skeletal muscle, perinatal | 8972 | -0.022 | -0.3573 | No |
| 18 | ACTA2 | ACTA2 Entrez, Source | actin, alpha 2, smooth muscle, aorta | 12081 | -0.091 | -0.5648 | No |
| 19 | ACTN4 | ACTN4 Entrez, Source | actinin, alpha 4 | 12842 | -0.155 | -0.5779 | Yes |
| 20 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 12980 | -0.185 | -0.5358 | Yes |
| 21 | TMOD1 | TMOD1 Entrez, Source | tropomodulin 1 | 12990 | -0.186 | -0.4836 | Yes |
| 22 | TPM4 | TPM4 Entrez, Source | tropomyosin 4 | 13032 | -0.200 | -0.4299 | Yes |
| 23 | VIM | VIM Entrez, Source | vimentin | 13040 | -0.204 | -0.3726 | Yes |
| 24 | ACTN3 | ACTN3 Entrez, Source | actinin, alpha 3 | 13042 | -0.204 | -0.3147 | Yes |
| 25 | ACTA1 | ACTA1 Entrez, Source | actin, alpha 1, skeletal muscle | 13342 | -1.187 | -0.0000 | Yes |
