Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_48h_versus_single_gel_48h.class.cls
#double_gel_48h_versus_single_gel_48h_repos
Phenotypeclass.cls#double_gel_48h_versus_single_gel_48h_repos
Upregulated in classsingle_gel_48h
GeneSetSTRUCTURAL_MOLECULE_ACTIVITY
Enrichment Score (ES)-0.49563694
Normalized Enrichment Score (NES)-1.8921958
Nominal p-value0.0
FDR q-value0.024833657
FWER p-Value0.679
Table: GSEA Results Summary



Fig 1: Enrichment plot: STRUCTURAL_MOLECULE_ACTIVITY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1PRELPPRELP
Entrez,  Source
proline/arginine-rich end leucine-rich repeat protein2240.1660.0054No
2FBN1FBN1
Entrez,  Source
fibrillin 14230.1330.0083No
3MATN1MATN1
Entrez,  Source
matrilin 1, cartilage matrix protein6140.1170.0097No
4SEPT5SEPT5
Entrez,  Source
septin 56450.1160.0231No
5MAPK8IP2MAPK8IP2
Entrez,  Source
mitogen-activated protein kinase 8 interacting protein 215890.077-0.0378No
6BFSP1BFSP1
Entrez,  Source
beaded filament structural protein 1, filensin16390.076-0.0313No
7TTNTTN
Entrez,  Source
titin16950.074-0.0255No
8CORO1ACORO1A
Entrez,  Source
coronin, actin binding protein, 1A19290.070-0.0337No
9DMDDMD
Entrez,  Source
dystrophin (muscular dystrophy, Duchenne and Becker types)19340.070-0.0247No
10MYOM1MYOM1
Entrez,  Source
myomesin 1 (skelemin) 185kDa20240.067-0.0223No
11MYH6MYH6
Entrez,  Source
myosin, heavy chain 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1)20660.067-0.0165No
12MYBPC1MYBPC1
Entrez,  Source
myosin binding protein C, slow type22690.063-0.0233No
13DSPPDSPP
Entrez,  Source
dentin sialophosphoprotein23650.061-0.0223No
14FBLN2FBLN2
Entrez,  Source
fibulin 224630.059-0.0216No
15MGPMGP
Entrez,  Source
matrix Gla protein25800.057-0.0227No
16MYOCMYOC
Entrez,  Source
myocilin, trabecular meshwork inducible glucocorticoid response26370.056-0.0194No
17MYH11MYH11
Entrez,  Source
myosin, heavy chain 11, smooth muscle26960.055-0.0163No
18MYL2MYL2
Entrez,  Source
myosin, light chain 2, regulatory, cardiac, slow27050.055-0.0095No
19CHI3L1CHI3L1
Entrez,  Source
chitinase 3-like 1 (cartilage glycoprotein-39)28780.052-0.0155No
20IMPG2IMPG2
Entrez,  Source
interphotoreceptor matrix proteoglycan 230030.050-0.0182No
21PLEC1PLEC1
Entrez,  Source
plectin 1, intermediate filament binding protein 500kDa31800.048-0.0251No
22MRPS7MRPS7
Entrez,  Source
mitochondrial ribosomal protein S741580.034-0.0944No
23MYH7MYH7
Entrez,  Source
myosin, heavy chain 7, cardiac muscle, beta44540.031-0.1126No
24SMTNSMTN
Entrez,  Source
smoothelin45960.029-0.1194No
25MRPL12MRPL12
Entrez,  Source
mitochondrial ribosomal protein L1248970.025-0.1387No
26RPL21RPL21
Entrez,  Source
ribosomal protein L2150040.024-0.1435No
27GFAPGFAP
Entrez,  Source
glial fibrillary acidic protein50670.023-0.1451No
28MYL3MYL3
Entrez,  Source
myosin, light chain 3, alkali; ventricular, skeletal, slow52480.021-0.1559No
29MEPEMEPE
Entrez,  Source
matrix, extracellular phosphoglycoprotein with ASARM motif (bone)54260.019-0.1668No
30RPLP1RPLP1
Entrez,  Source
ribosomal protein, large, P155550.018-0.1741No
31RPL4RPL4
Entrez,  Source
ribosomal protein L456780.016-0.1811No
32ACTL7BACTL7B
Entrez,  Source
actin-like 7B58770.014-0.1942No
33MYBPHMYBPH
Entrez,  Source
myosin binding protein H58940.014-0.1935No
34RPL14RPL14
Entrez,  Source
ribosomal protein L1461180.012-0.2088No
35RPS3ARPS3A
Entrez,  Source
ribosomal protein S3A61700.011-0.2111No
36RPS24RPS24
Entrez,  Source
ribosomal protein S2461810.011-0.2104No
37RPS26RPS26
Entrez,  Source
ribosomal protein S2661930.011-0.2098No
38RPL8RPL8
Entrez,  Source
ribosomal protein L862360.010-0.2115No
39RPS2RPS2
Entrez,  Source
ribosomal protein S262630.010-0.2121No
40RPL39RPL39
Entrez,  Source
ribosomal protein L3962670.010-0.2110No
41RPL18RPL18
Entrez,  Source
ribosomal protein L1862910.010-0.2114No
42RPS14RPS14
Entrez,  Source
ribosomal protein S1463190.009-0.2122No
43RPS15ARPS15A
Entrez,  Source
ribosomal protein S15a63360.009-0.2122No
44RPS15RPS15
Entrez,  Source
ribosomal protein S1563690.009-0.2134No
45RPL7RPL7
Entrez,  Source
ribosomal protein L763720.009-0.2123No
46RPS3RPS3
Entrez,  Source
ribosomal protein S363900.009-0.2125No
47IVLIVL
Entrez,  Source
involucrin64340.008-0.2146No
48ADD3ADD3
Entrez,  Source
adducin 3 (gamma)64720.008-0.2164No
49RPL35RPL35
Entrez,  Source
ribosomal protein L3564910.008-0.2167No
50RPL41RPL41
Entrez,  Source
ribosomal protein L4165830.007-0.2227No
51SPAG4SPAG4
Entrez,  Source
sperm associated antigen 465960.007-0.2227No
52RPS20RPS20
Entrez,  Source
ribosomal protein S2065980.006-0.2219No
53RPS25RPS25
Entrez,  Source
ribosomal protein S2566640.006-0.2261No
54RPL9RPL9
Entrez,  Source
ribosomal protein L966840.006-0.2267No
55RPS16RPS16
Entrez,  Source
ribosomal protein S1667070.005-0.2277No
56MALMAL
Entrez,  Source
mal, T-cell differentiation protein67790.004-0.2325No
57RPL6RPL6
Entrez,  Source
ribosomal protein L668270.004-0.2355No
58SORBS3SORBS3
Entrez,  Source
sorbin and SH3 domain containing 368910.003-0.2399No
59RPL27RPL27
Entrez,  Source
ribosomal protein L2769000.003-0.2400No
60RPS8RPS8
Entrez,  Source
ribosomal protein S869060.003-0.2400No
61MATR3MATR3
Entrez,  Source
matrin 369310.003-0.2415No
62RPL24RPL24
Entrez,  Source
ribosomal protein L2469390.003-0.2417No
63RPS21RPS21
Entrez,  Source
ribosomal protein S2169420.003-0.2415No
64ANK1ANK1
Entrez,  Source
ankyrin 1, erythrocytic70020.002-0.2457No
65RPS12RPS12
Entrez,  Source
ribosomal protein S1270320.002-0.2477No
66RPS9RPS9
Entrez,  Source
ribosomal protein S970430.002-0.2482No
67RPS4XRPS4X
Entrez,  Source
ribosomal protein S4, X-linked70630.001-0.2495No
68RPS29RPS29
Entrez,  Source
ribosomal protein S2970760.001-0.2502No
69RPS6RPS6
Entrez,  Source
ribosomal protein S671800.000-0.2580No
70RPS17RPS17
Entrez,  Source
ribosomal protein S177191-0.000-0.2588No
71NUMA1NUMA1
Entrez,  Source
nuclear mitotic apparatus protein 17275-0.001-0.2649No
72RPS23RPS23
Entrez,  Source
ribosomal protein S237280-0.001-0.2650No
73RPL26RPL26
Entrez,  Source
ribosomal protein L267324-0.002-0.2681No
74RPS5RPS5
Entrez,  Source
ribosomal protein S57352-0.002-0.2698No
75SEPT7SEPT7
Entrez,  Source
septin 77371-0.002-0.2709No
76RPS27RPS27
Entrez,  Source
ribosomal protein S27 (metallopanstimulin 1)7399-0.003-0.2726No
77RPL13RPL13
Entrez,  Source
ribosomal protein L137409-0.003-0.2729No
78RPL29RPL29
Entrez,  Source
ribosomal protein L297446-0.003-0.2752No
79RPL31RPL31
Entrez,  Source
ribosomal protein L317458-0.003-0.2756No
80RPS11RPS11
Entrez,  Source
ribosomal protein S117504-0.004-0.2785No
81RPL15RPL15
Entrez,  Source
ribosomal protein L157516-0.004-0.2788No
82RPL3RPL3
Entrez,  Source
ribosomal protein L37626-0.005-0.2864No
83RPL13ARPL13A
Entrez,  Source
ribosomal protein L13a7679-0.006-0.2896No
84RPL37RPL37
Entrez,  Source
ribosomal protein L377734-0.006-0.2928No
85RPL5RPL5
Entrez,  Source
ribosomal protein L57825-0.007-0.2987No
86RPS13RPS13
Entrez,  Source
ribosomal protein S137844-0.008-0.2990No
87RPS19RPS19
Entrez,  Source
ribosomal protein S197848-0.008-0.2982No
88RPS18RPS18
Entrez,  Source
ribosomal protein S187876-0.008-0.2992No
89RPL19RPL19
Entrez,  Source
ribosomal protein L197877-0.008-0.2981No
90RPL11RPL11
Entrez,  Source
ribosomal protein L117917-0.008-0.2999No
91FBN2FBN2
Entrez,  Source
fibrillin 2 (congenital contractural arachnodactyly)8235-0.012-0.3222No
92RPL22RPL22
Entrez,  Source
ribosomal protein L228557-0.016-0.3443No
93DESDES
Entrez,  Source
desmin8619-0.017-0.3467No
94RPL30RPL30
Entrez,  Source
ribosomal protein L308669-0.018-0.3480No
95RPL28RPL28
Entrez,  Source
ribosomal protein L288709-0.018-0.3485No
96RPS10RPS10
Entrez,  Source
ribosomal protein S108840-0.020-0.3557No
97MRPL23MRPL23
Entrez,  Source
mitochondrial ribosomal protein L239114-0.023-0.3732No
98IMPG1IMPG1
Entrez,  Source
interphotoreceptor matrix proteoglycan 19151-0.024-0.3727No
99MRPL41MRPL41
Entrez,  Source
mitochondrial ribosomal protein L419592-0.030-0.4019No
100SEPT4SEPT4
Entrez,  Source
septin 410191-0.040-0.4418No
101ODF2ODF2
Entrez,  Source
outer dense fiber of sperm tails 210350-0.042-0.4481No
102TUBG1TUBG1
Entrez,  Source
tubulin, gamma 110526-0.046-0.4551No
103COL4A4COL4A4
Entrez,  Source
collagen, type IV, alpha 410867-0.053-0.4737No
104MPZL1MPZL1
Entrez,  Source
myelin protein zero-like 110998-0.056-0.4760No
105BFARBFAR
Entrez,  Source
bifunctional apoptosis regulator11056-0.057-0.4727No
106COMPCOMP
Entrez,  Source
cartilage oligomeric matrix protein11234-0.061-0.4779No
107ACTBACTB
Entrez,  Source
actin, beta11264-0.061-0.4718No
108HIP1HIP1
Entrez,  Source
huntingtin interacting protein 111319-0.063-0.4674No
109SPTBN4SPTBN4
Entrez,  Source
spectrin, beta, non-erythrocytic 411326-0.063-0.4594No
110MAPTMAPT
Entrez,  Source
microtubule-associated protein tau11785-0.078-0.4835Yes
111EFEMP2EFEMP2
Entrez,  Source
EGF-containing fibulin-like extracellular matrix protein 211825-0.080-0.4756Yes
112ARPC5ARPC5
Entrez,  Source
actin related protein 2/3 complex, subunit 5, 16kDa12047-0.089-0.4803Yes
113DSPDSP
Entrez,  Source
desmoplakin12225-0.098-0.4804Yes
114TFPI2TFPI2
Entrez,  Source
tissue factor pathway inhibitor 212427-0.112-0.4805Yes
115NEFLNEFL
Entrez,  Source
neurofilament, light polypeptide 68kDa12514-0.118-0.4711Yes
116ARPC1BARPC1B
Entrez,  Source
actin related protein 2/3 complex, subunit 1B, 41kDa12732-0.139-0.4688Yes
117ACTC1ACTC1
Entrez,  Source
actin, alpha, cardiac muscle 112741-0.140-0.4506Yes
118SORBS2SORBS2
Entrez,  Source
sorbin and SH3 domain containing 212750-0.141-0.4322Yes
119TPM1TPM1
Entrez,  Source
tropomyosin 1 (alpha)12980-0.185-0.4247Yes
120LAMC1LAMC1
Entrez,  Source
laminin, gamma 1 (formerly LAMB2)13024-0.196-0.4015Yes
121TPM4TPM4
Entrez,  Source
tropomyosin 413032-0.200-0.3751Yes
122VIMVIM
Entrez,  Source
vimentin13040-0.204-0.3482Yes
123ACTN3ACTN3
Entrez,  Source
actinin, alpha 313042-0.204-0.3208Yes
124LMNB1LMNB1
Entrez,  Source
lamin B113104-0.234-0.2939Yes
125ANXA1ANXA1
Entrez,  Source
annexin A113312-0.498-0.2424Yes
126MSNMSN
Entrez,  Source
moesin13327-0.629-0.1588Yes
127ACTA1ACTA1
Entrez,  Source
actin, alpha 1, skeletal muscle13342-1.1870.0000Yes
Table: GSEA details [plain text format]



Fig 2: STRUCTURAL_MOLECULE_ACTIVITY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: STRUCTURAL_MOLECULE_ACTIVITY: Random ES distribution   
Gene set null distribution of ES for STRUCTURAL_MOLECULE_ACTIVITY