Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | TCELL_ANERGIC_UP |
| Enrichment Score (ES) | -0.5516172 |
| Normalized Enrichment Score (NES) | -1.7695354 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.046769068 |
| FWER p-Value | 0.994 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | EGR2 | EGR2 Entrez, Source | early growth response 2 (Krox-20 homolog, Drosophila) | 66 | 0.256 | 0.0469 | No |
| 2 | CTSE | CTSE Entrez, Source | cathepsin E | 170 | 0.184 | 0.0766 | No |
| 3 | GCH1 | GCH1 Entrez, Source | GTP cyclohydrolase 1 (dopa-responsive dystonia) | 441 | 0.131 | 0.0828 | No |
| 4 | GABRA4 | GABRA4 Entrez, Source | gamma-aminobutyric acid (GABA) A receptor, alpha 4 | 1013 | 0.097 | 0.0595 | No |
| 5 | FYN | FYN Entrez, Source | FYN oncogene related to SRC, FGR, YES | 1682 | 0.075 | 0.0244 | No |
| 6 | TNFSF9 | TNFSF9 Entrez, Source | tumor necrosis factor (ligand) superfamily, member 9 | 1683 | 0.075 | 0.0396 | No |
| 7 | CASP4 | CASP4 Entrez, Source | caspase 4, apoptosis-related cysteine peptidase | 1853 | 0.071 | 0.0413 | No |
| 8 | ARFIP1 | ARFIP1 Entrez, Source | ADP-ribosylation factor interacting protein 1 (arfaptin 1) | 3191 | 0.047 | -0.0497 | No |
| 9 | SLC29A3 | SLC29A3 Entrez, Source | solute carrier family 29 (nucleoside transporters), member 3 | 3407 | 0.044 | -0.0568 | No |
| 10 | PRG1 | PRG1 Entrez, Source | proteoglycan 1, secretory granule | 3518 | 0.043 | -0.0564 | No |
| 11 | KCNJ11 | KCNJ11 Entrez, Source | potassium inwardly-rectifying channel, subfamily J, member 11 | 3807 | 0.039 | -0.0701 | No |
| 12 | ADORA2A | ADORA2A Entrez, Source | adenosine A2a receptor | 3872 | 0.038 | -0.0672 | No |
| 13 | MYH14 | MYH14 Entrez, Source | myosin, heavy chain 14 | 4146 | 0.034 | -0.0807 | No |
| 14 | TEKT2 | TEKT2 Entrez, Source | tektin 2 (testicular) | 5035 | 0.023 | -0.1428 | No |
| 15 | CSF1 | CSF1 Entrez, Source | colony stimulating factor 1 (macrophage) | 5308 | 0.020 | -0.1591 | No |
| 16 | CD97 | CD97 Entrez, Source | CD97 molecule | 6745 | 0.005 | -0.2661 | No |
| 17 | NR4A2 | NR4A2 Entrez, Source | nuclear receptor subfamily 4, group A, member 2 | 6791 | 0.004 | -0.2687 | No |
| 18 | HLF | HLF Entrez, Source | hepatic leukemia factor | 6819 | 0.004 | -0.2699 | No |
| 19 | TNFRSF4 | TNFRSF4 Entrez, Source | tumor necrosis factor receptor superfamily, member 4 | 6831 | 0.004 | -0.2699 | No |
| 20 | PLA2G10 | PLA2G10 Entrez, Source | phospholipase A2, group X | 6860 | 0.004 | -0.2713 | No |
| 21 | SFRP4 | SFRP4 Entrez, Source | secreted frizzled-related protein 4 | 6996 | 0.002 | -0.2811 | No |
| 22 | ANGPTL2 | ANGPTL2 Entrez, Source | angiopoietin-like 2 | 7080 | 0.001 | -0.2871 | No |
| 23 | AGT | AGT Entrez, Source | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 7909 | -0.008 | -0.3477 | No |
| 24 | JAK3 | JAK3 Entrez, Source | Janus kinase 3 (a protein tyrosine kinase, leukocyte) | 8088 | -0.010 | -0.3590 | No |
| 25 | BNIP3 | BNIP3 Entrez, Source | BCL2/adenovirus E1B 19kDa interacting protein 3 | 8690 | -0.018 | -0.4005 | No |
| 26 | MARCH2 | MARCH2 Entrez, Source | membrane-associated ring finger (C3HC4) 2 | 8936 | -0.021 | -0.4147 | No |
| 27 | ING4 | ING4 Entrez, Source | inhibitor of growth family, member 4 | 9821 | -0.034 | -0.4743 | No |
| 28 | ZFP36L1 | ZFP36L1 Entrez, Source | zinc finger protein 36, C3H type-like 1 | 10023 | -0.037 | -0.4820 | No |
| 29 | IER3 | IER3 Entrez, Source | immediate early response 3 | 10439 | -0.044 | -0.5042 | No |
| 30 | GADD45B | GADD45B Entrez, Source | growth arrest and DNA-damage-inducible, beta | 10614 | -0.047 | -0.5077 | No |
| 31 | TINAG | TINAG Entrez, Source | tubulointerstitial nephritis antigen | 10796 | -0.051 | -0.5109 | No |
| 32 | JUP | JUP Entrez, Source | junction plakoglobin | 10892 | -0.053 | -0.5072 | No |
| 33 | NR4A3 | NR4A3 Entrez, Source | nuclear receptor subfamily 4, group A, member 3 | 10905 | -0.054 | -0.4972 | No |
| 34 | ANP32A | ANP32A Entrez, Source | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 10934 | -0.054 | -0.4882 | No |
| 35 | NOTCH1 | NOTCH1 Entrez, Source | Notch homolog 1, translocation-associated (Drosophila) | 11455 | -0.067 | -0.5139 | No |
| 36 | GGA2 | GGA2 Entrez, Source | golgi associated, gamma adaptin ear containing, ARF binding protein 2 | 11752 | -0.077 | -0.5205 | No |
| 37 | TNFSF11 | TNFSF11 Entrez, Source | tumor necrosis factor (ligand) superfamily, member 11 | 12167 | -0.095 | -0.5324 | Yes |
| 38 | FOXP1 | FOXP1 Entrez, Source | forkhead box P1 | 12207 | -0.097 | -0.5156 | Yes |
| 39 | DUSP6 | DUSP6 Entrez, Source | dual specificity phosphatase 6 | 12330 | -0.106 | -0.5033 | Yes |
| 40 | KIFC3 | KIFC3 Entrez, Source | kinesin family member C3 | 12529 | -0.120 | -0.4939 | Yes |
| 41 | MYO1E | MYO1E Entrez, Source | myosin IE | 12727 | -0.138 | -0.4807 | Yes |
| 42 | ACTN4 | ACTN4 Entrez, Source | actinin, alpha 4 | 12842 | -0.155 | -0.4579 | Yes |
| 43 | MYO1C | MYO1C Entrez, Source | myosin IC | 12992 | -0.186 | -0.4313 | Yes |
| 44 | F2R | F2R Entrez, Source | coagulation factor II (thrombin) receptor | 13224 | -0.321 | -0.3835 | Yes |
| 45 | ADORA2B | ADORA2B Entrez, Source | adenosine A2b receptor | 13236 | -0.333 | -0.3167 | Yes |
| 46 | DDR1 | DDR1 Entrez, Source | discoidin domain receptor family, member 1 | 13240 | -0.338 | -0.2483 | Yes |
| 47 | NDRG1 | NDRG1 Entrez, Source | N-myc downstream regulated gene 1 | 13242 | -0.345 | -0.1784 | Yes |
| 48 | STX11 | STX11 Entrez, Source | syntaxin 11 | 13278 | -0.399 | -0.1000 | Yes |
| 49 | PFKP | PFKP Entrez, Source | phosphofructokinase, platelet | 13318 | -0.516 | 0.0018 | Yes |
