Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | TGFBETA_EARLY_UP |
| Enrichment Score (ES) | -0.59646106 |
| Normalized Enrichment Score (NES) | -1.8224486 |
| Nominal p-value | 0.0016393443 |
| FDR q-value | 0.03764768 |
| FWER p-Value | 0.937 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | MMP3 | MMP3 Entrez, Source | matrix metallopeptidase 3 (stromelysin 1, progelatinase) | 351 | 0.142 | 0.0056 | No |
| 2 | ITGB5 | ITGB5 Entrez, Source | integrin, beta 5 | 1194 | 0.090 | -0.0375 | No |
| 3 | LRP1 | LRP1 Entrez, Source | low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) | 1632 | 0.076 | -0.0531 | No |
| 4 | CDH6 | CDH6 Entrez, Source | cadherin 6, type 2, K-cadherin (fetal kidney) | 1638 | 0.076 | -0.0364 | No |
| 5 | LRRC17 | LRRC17 Entrez, Source | leucine rich repeat containing 17 | 1657 | 0.075 | -0.0207 | No |
| 6 | RHOB | RHOB Entrez, Source | ras homolog gene family, member B | 1840 | 0.071 | -0.0183 | No |
| 7 | COL1A2 | COL1A2 Entrez, Source | collagen, type I, alpha 2 | 2001 | 0.068 | -0.0149 | No |
| 8 | ITGB2 | ITGB2 Entrez, Source | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | 2233 | 0.063 | -0.0180 | No |
| 9 | IGFBP3 | IGFBP3 Entrez, Source | insulin-like growth factor binding protein 3 | 2407 | 0.060 | -0.0174 | No |
| 10 | SPARC | SPARC Entrez, Source | secreted protein, acidic, cysteine-rich (osteonectin) | 2588 | 0.057 | -0.0181 | No |
| 11 | IGFBP5 | IGFBP5 Entrez, Source | insulin-like growth factor binding protein 5 | 2629 | 0.056 | -0.0084 | No |
| 12 | IGFBP2 | IGFBP2 Entrez, Source | insulin-like growth factor binding protein 2, 36kDa | 3303 | 0.046 | -0.0487 | No |
| 13 | NOTCH2 | NOTCH2 Entrez, Source | Notch homolog 2 (Drosophila) | 3652 | 0.041 | -0.0656 | No |
| 14 | DVL1 | DVL1 Entrez, Source | dishevelled, dsh homolog 1 (Drosophila) | 5003 | 0.024 | -0.1617 | No |
| 15 | NID1 | NID1 Entrez, Source | nidogen 1 | 6040 | 0.012 | -0.2367 | No |
| 16 | COL3A1 | COL3A1 Entrez, Source | collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) | 6389 | 0.009 | -0.2609 | No |
| 17 | FN1 | FN1 Entrez, Source | fibronectin 1 | 7215 | -0.000 | -0.3229 | No |
| 18 | ARHGDIA | ARHGDIA Entrez, Source | Rho GDP dissociation inhibitor (GDI) alpha | 8158 | -0.011 | -0.3911 | No |
| 19 | ICAM1 | ICAM1 Entrez, Source | intercellular adhesion molecule 1 (CD54), human rhinovirus receptor | 8686 | -0.018 | -0.4267 | No |
| 20 | BSG | BSG Entrez, Source | basigin (Ok blood group) | 9210 | -0.025 | -0.4605 | No |
| 21 | RND3 | RND3 Entrez, Source | Rho family GTPase 3 | 9751 | -0.033 | -0.4937 | No |
| 22 | RHOA | RHOA Entrez, Source | ras homolog gene family, member A | 10584 | -0.047 | -0.5457 | No |
| 23 | JUP | JUP Entrez, Source | junction plakoglobin | 10892 | -0.053 | -0.5567 | No |
| 24 | PAK1 | PAK1 Entrez, Source | p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast) | 11055 | -0.057 | -0.5560 | No |
| 25 | CSPG2 | CSPG2 Entrez, Source | chondroitin sulfate proteoglycan 2 (versican) | 11206 | -0.060 | -0.5537 | No |
| 26 | WNT2B | WNT2B Entrez, Source | wingless-type MMTV integration site family, member 2B | 11418 | -0.066 | -0.5547 | No |
| 27 | MMP14 | MMP14 Entrez, Source | matrix metallopeptidase 14 (membrane-inserted) | 11798 | -0.079 | -0.5654 | No |
| 28 | RHOG | RHOG Entrez, Source | ras homolog gene family, member G (rho G) | 12212 | -0.097 | -0.5745 | Yes |
| 29 | CD59 | CD59 Entrez, Source | CD59 molecule, complement regulatory protein | 12353 | -0.107 | -0.5608 | Yes |
| 30 | IGF2R | IGF2R Entrez, Source | insulin-like growth factor 2 receptor | 12385 | -0.110 | -0.5383 | Yes |
| 31 | PXN | PXN Entrez, Source | paxillin | 12950 | -0.176 | -0.5411 | Yes |
| 32 | CD44 | CD44 Entrez, Source | CD44 molecule (Indian blood group) | 12977 | -0.184 | -0.5016 | Yes |
| 33 | RHOQ | RHOQ Entrez, Source | ras homolog gene family, member Q | 13049 | -0.206 | -0.4604 | Yes |
| 34 | ZYX | ZYX Entrez, Source | zyxin | 13115 | -0.238 | -0.4115 | Yes |
| 35 | TIMP1 | TIMP1 Entrez, Source | TIMP metallopeptidase inhibitor 1 | 13187 | -0.286 | -0.3525 | Yes |
| 36 | PLAT | PLAT Entrez, Source | plasminogen activator, tissue | 13241 | -0.343 | -0.2790 | Yes |
| 37 | SERPINE1 | SERPINE1 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 13308 | -0.484 | -0.1748 | Yes |
| 38 | MARCKSL1 | MARCKSL1 Entrez, Source | MARCKS-like 1 | 13335 | -0.786 | 0.0005 | Yes |
