Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | TNFALPHA_ADIP_DN |
| Enrichment Score (ES) | 0.4521859 |
| Normalized Enrichment Score (NES) | 1.5893835 |
| Nominal p-value | 0.009852217 |
| FDR q-value | 0.09827234 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FASN | FASN Entrez, Source | fatty acid synthase | 60 | 0.267 | 0.0670 | Yes |
| 2 | G0S2 | G0S2 Entrez, Source | G0/G1switch 2 | 98 | 0.228 | 0.1251 | Yes |
| 3 | RASD1 | RASD1 Entrez, Source | RAS, dexamethasone-induced 1 | 200 | 0.173 | 0.1637 | Yes |
| 4 | ACOX1 | ACOX1 Entrez, Source | acyl-Coenzyme A oxidase 1, palmitoyl | 227 | 0.165 | 0.2058 | Yes |
| 5 | PEX11A | PEX11A Entrez, Source | peroxisomal biogenesis factor 11A | 241 | 0.161 | 0.2479 | Yes |
| 6 | PC | PC Entrez, Source | pyruvate carboxylase | 270 | 0.155 | 0.2871 | Yes |
| 7 | ALAS1 | ALAS1 Entrez, Source | aminolevulinate, delta-, synthase 1 | 300 | 0.149 | 0.3249 | Yes |
| 8 | TST | TST Entrez, Source | thiosulfate sulfurtransferase (rhodanese) | 446 | 0.130 | 0.3488 | Yes |
| 9 | PFKFB1 | PFKFB1 Entrez, Source | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 | 476 | 0.127 | 0.3806 | Yes |
| 10 | ACSL1 | ACSL1 Entrez, Source | acyl-CoA synthetase long-chain family member 1 | 564 | 0.121 | 0.4063 | Yes |
| 11 | PPARG | PPARG Entrez, Source | peroxisome proliferative activated receptor, gamma | 801 | 0.107 | 0.4171 | Yes |
| 12 | SLC2A4 | SLC2A4 Entrez, Source | solute carrier family 2 (facilitated glucose transporter), member 4 | 900 | 0.102 | 0.4371 | Yes |
| 13 | NR1H3 | NR1H3 Entrez, Source | nuclear receptor subfamily 1, group H, member 3 | 1041 | 0.096 | 0.4522 | Yes |
| 14 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 1493 | 0.080 | 0.4395 | No |
| 15 | CIB2 | CIB2 Entrez, Source | calcium and integrin binding family member 2 | 1622 | 0.077 | 0.4504 | No |
| 16 | BCKDHA | BCKDHA Entrez, Source | branched chain keto acid dehydrogenase E1, alpha polypeptide | 2252 | 0.063 | 0.4199 | No |
| 17 | ALAD | ALAD Entrez, Source | aminolevulinate, delta-, dehydratase | 2787 | 0.054 | 0.3941 | No |
| 18 | ENTPD5 | ENTPD5 Entrez, Source | ectonucleoside triphosphate diphosphohydrolase 5 | 2975 | 0.050 | 0.3935 | No |
| 19 | HIPK3 | HIPK3 Entrez, Source | homeodomain interacting protein kinase 3 | 3217 | 0.047 | 0.3879 | No |
| 20 | COL15A1 | COL15A1 Entrez, Source | collagen, type XV, alpha 1 | 3242 | 0.047 | 0.3986 | No |
| 21 | AK2 | AK2 Entrez, Source | adenylate kinase 2 | 3549 | 0.042 | 0.3869 | No |
| 22 | IDH3G | IDH3G Entrez, Source | isocitrate dehydrogenase 3 (NAD+) gamma | 3649 | 0.041 | 0.3904 | No |
| 23 | DBI | DBI Entrez, Source | diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein) | 3877 | 0.038 | 0.3836 | No |
| 24 | IDH1 | IDH1 Entrez, Source | isocitrate dehydrogenase 1 (NADP+), soluble | 3953 | 0.037 | 0.3879 | No |
| 25 | DHRS3 | DHRS3 Entrez, Source | dehydrogenase/reductase (SDR family) member 3 | 4134 | 0.035 | 0.3836 | No |
| 26 | AQP7 | AQP7 Entrez, Source | aquaporin 7 | 4534 | 0.030 | 0.3615 | No |
| 27 | ADIPOQ | ADIPOQ Entrez, Source | adiponectin, C1Q and collagen domain containing | 5211 | 0.021 | 0.3164 | No |
| 28 | PLA2G6 | PLA2G6 Entrez, Source | phospholipase A2, group VI (cytosolic, calcium-independent) | 5243 | 0.021 | 0.3197 | No |
| 29 | NFS1 | NFS1 Entrez, Source | NFS1 nitrogen fixation 1 (S. cerevisiae) | 5674 | 0.016 | 0.2917 | No |
| 30 | TALDO1 | TALDO1 Entrez, Source | transaldolase 1 | 5840 | 0.014 | 0.2832 | No |
| 31 | ACADM | ACADM Entrez, Source | acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain | 5845 | 0.014 | 0.2867 | No |
| 32 | CDKN2C | CDKN2C Entrez, Source | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 7160 | 0.000 | 0.1880 | No |
| 33 | LTC4S | LTC4S Entrez, Source | leukotriene C4 synthase | 7935 | -0.009 | 0.1322 | No |
| 34 | ACADS | ACADS Entrez, Source | acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain | 7949 | -0.009 | 0.1336 | No |
| 35 | ECH1 | ECH1 Entrez, Source | enoyl Coenzyme A hydratase 1, peroxisomal | 8150 | -0.011 | 0.1215 | No |
| 36 | SCARB1 | SCARB1 Entrez, Source | scavenger receptor class B, member 1 | 9712 | -0.032 | 0.0128 | No |
| 37 | DGAT1 | DGAT1 Entrez, Source | diacylglycerol O-acyltransferase homolog 1 (mouse) | 10079 | -0.038 | -0.0046 | No |
| 38 | ABCD2 | ABCD2 Entrez, Source | ATP-binding cassette, sub-family D (ALD), member 2 | 10245 | -0.041 | -0.0061 | No |
| 39 | TPP2 | TPP2 Entrez, Source | tripeptidyl peptidase II | 10260 | -0.041 | 0.0037 | No |
| 40 | FAM62A | FAM62A Entrez, Source | family with sequence similarity 62 (C2 domain containing), member A | 10756 | -0.051 | -0.0200 | No |
| 41 | ITGA6 | ITGA6 Entrez, Source | integrin, alpha 6 | 12716 | -0.137 | -0.1307 | No |
| 42 | SELENBP1 | SELENBP1 Entrez, Source | selenium binding protein 1 | 12740 | -0.140 | -0.0951 | No |
| 43 | RGS2 | RGS2 Entrez, Source | regulator of G-protein signalling 2, 24kDa | 13320 | -0.525 | 0.0017 | No |
