Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | TNFR1PATHWAY |
| Enrichment Score (ES) | -0.6715501 |
| Normalized Enrichment Score (NES) | -1.8058321 |
| Nominal p-value | 0.0036231885 |
| FDR q-value | 0.04205865 |
| FWER p-Value | 0.967 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | DFFB | DFFB Entrez, Source | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) | 2159 | 0.065 | -0.1153 | No |
| 2 | TNFRSF1A | TNFRSF1A Entrez, Source | tumor necrosis factor receptor superfamily, member 1A | 2994 | 0.050 | -0.1417 | No |
| 3 | ARHGDIB | ARHGDIB Entrez, Source | Rho GDP dissociation inhibitor (GDI) beta | 6080 | 0.012 | -0.3646 | No |
| 4 | TNF | TNF Entrez, Source | tumor necrosis factor (TNF superfamily, member 2) | 6778 | 0.004 | -0.4137 | No |
| 5 | JUN | JUN Entrez, Source | jun oncogene | 8081 | -0.010 | -0.5039 | No |
| 6 | MAP2K4 | MAP2K4 Entrez, Source | mitogen-activated protein kinase kinase 4 | 10315 | -0.042 | -0.6414 | Yes |
| 7 | DFFA | DFFA Entrez, Source | DNA fragmentation factor, 45kDa, alpha polypeptide | 10349 | -0.042 | -0.6133 | Yes |
| 8 | FADD | FADD Entrez, Source | Fas (TNFRSF6)-associated via death domain | 10437 | -0.044 | -0.5880 | Yes |
| 9 | MAP3K1 | MAP3K1 Entrez, Source | mitogen-activated protein kinase kinase kinase 1 | 10643 | -0.048 | -0.5689 | Yes |
| 10 | BAG4 | BAG4 Entrez, Source | BCL2-associated athanogene 4 | 10691 | -0.049 | -0.5370 | Yes |
| 11 | TRADD | TRADD Entrez, Source | TNFRSF1A-associated via death domain | 11038 | -0.057 | -0.5220 | Yes |
| 12 | PAK1 | PAK1 Entrez, Source | p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast) | 11055 | -0.057 | -0.4820 | Yes |
| 13 | MADD | MADD Entrez, Source | MAP-kinase activating death domain | 11375 | -0.064 | -0.4595 | Yes |
| 14 | CASP8 | CASP8 Entrez, Source | caspase 8, apoptosis-related cysteine peptidase | 11387 | -0.065 | -0.4135 | Yes |
| 15 | RB1 | RB1 Entrez, Source | retinoblastoma 1 (including osteosarcoma) | 11401 | -0.065 | -0.3674 | Yes |
| 16 | CASP3 | CASP3 Entrez, Source | caspase 3, apoptosis-related cysteine peptidase | 12003 | -0.087 | -0.3497 | Yes |
| 17 | PAK2 | PAK2 Entrez, Source | p21 (CDKN1A)-activated kinase 2 | 12118 | -0.092 | -0.2916 | Yes |
| 18 | LMNA | LMNA Entrez, Source | lamin A/C | 12554 | -0.122 | -0.2363 | Yes |
| 19 | CASP2 | CASP2 Entrez, Source | caspase 2, apoptosis-related cysteine peptidase (neural precursor cell expressed, developmentally down-regulated 2) | 12946 | -0.175 | -0.1394 | Yes |
| 20 | LMNB1 | LMNB1 Entrez, Source | lamin B1 | 13104 | -0.234 | 0.0179 | Yes |
